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X-ray energy spectrum plays an essential role in computed tomography (CT) imaging and related tasks. Due to the high photon flux of clinical CT scanners, most of spectrum estimation methods are indirect and usually suffered from various…

Medical Physics · Physics 2017-06-14 Wei Zhao , Lei Xing , Qiude Zhang , Qingguo Xie , Tianye Niu

The characteristics of an x-ray spectrum can greatly influence imaging and related tasks. In practice, due to the pile-up effect of the detector, it's difficult to directly measure the spectrum of a CT scanner using an energy resolved…

Medical Physics · Physics 2015-03-09 Wei Zhao , Kai Niu , Sebastian Schafer , Kevin Royalty

Dual-energy computed tomography (CT) is to reconstruct images of an object from two projection datasets generated from two distinct x-ray source energy spectra. It can provide more accurate attenuation quantification than conventional CT…

Medical Physics · Physics 2018-05-15 Wenxiang Cong , Daniel Harrison , Yan Xi , Ge Wang

Material decomposition refers to using the energy dependence of material physical properties to differentiate materials in a sample, which is a very important application in computed tomography(CT). In propagation-based X-ray phase-contrast…

Medical Physics · Physics 2023-12-01 Suyu Liao , Huitao Zhang , Peng Zhang , Yining Zhu

Dual-energy X-ray Computed Tomography (DECT) constitutes an advanced technology which enables automatic decomposition of materials in clinical images without manual segmentation using the dependency of the X-ray linear attenuation with…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Hang Xu , Alexandre Bousse , Alessandro Perelli

Dark-field imaging based on grating interferometry is an emerging X-ray modality in medical imaging, which is particularly capable of providing complementary diagnostic information by visualizing the microstructural properties of lung…

Medical Physics · Physics 2026-05-29 Longchao Men , Peiyuan Guo , Jincheng Lu , Yan Xu , Hongxia Yin , Zhenchang Wang , Li Zhang , Zhentian Wang

Inferior soft-tissue contrast resolution is a major limitation of current CT scanners. The aim of the study is to improve the contrast resolution of CT scanners using dual-energy acquisition. Based on dual-energy material decomposition, the…

Medical Physics · Physics 2016-11-15 Wei Zhao , Lu Wan , Bo Zhang , Qiude Zhang , Tianye Niu

Dual-energy computed tomography (DECT) enables material-specific imaging through acquisitions at two different X-ray energy spectra. Material decomposition from DECT data is an ill-posed inverse problem that is highly sensitive to noise…

Dual-energy imaging is a clinically well-established technique that offers several advantages over conventional X-ray imaging. By performing measurements with two distinct X-ray spectra, differences in energy-dependent attenuation are…

We propose a new modeling approach for scatter estimation and descattering in polyenergetic X-ray computed tomography (CT) based on fitting models to local neighborhoods of a training set. X-ray CT is widely used in medical and industrial…

Image and Video Processing · Electrical Eng. & Systems 2021-09-30 Michael T. McCann , Marc L. Klasky , Jennifer L. Schei , Saiprasad Ravishankar

Due to the energy-dependent nature of the attenuation coefficient and the polychromaticity of the X-ray source, beam hardening effect occurs when X-ray photons penetrate through an object, causing a nonlinear projection data. When a linear…

Medical Physics · Physics 2018-12-07 Wei Zhao , Dengwang Li , Kai Niu , Wenjian Qin , Hao Peng , Tianye Niu

Due to the merit of establishing volumetric data, X-ray computed tomography (XCT) is increasingly used as a non-destructive evaluation technique in the quality control of advanced manufactured parts with complex non-line-of-sight features.…

Many clinical applications depend critically on the accurate differentiation and classification of different types of materials in patient anatomy. This work introduces a unified framework for accurate nonlinear material decomposition and…

Medical Physics · Physics 2018-03-19 Wei Zhao , Don Vernekohl , Fei Han , Bin Han , Hao Peng , Lei Xing , James K Min

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

Medical Physics · Physics 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman

As computational tools for X-ray computed tomography (CT) become more quantitatively accurate, knowledge of the source-detector spectral response is critical for quantitative system-independent reconstruction and material characterization…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Wenrui Li , Venkatesh Sridhar , K. Aditya Mohan , Saransh Singh , Jean-Baptiste Forien , Xin Liu , Gregery T. Buzzard , Charles A. Bouman

We consider the problem of signal reconstruction for computed tomography (CT) under a nonlinear forward model that accounts for exponential signal attenuation, a polychromatic X-ray source, general measurement noise (e.g., Poisson shot…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Mengqi Lou , Kabir Aladin Verchand , Sara Fridovich-Keil , Ashwin Pananjady

By acquiring two sets of tomographic measurements at distinct X-ray spectra, the dual-energy CT (DECT) enables quantitative material-specific imaging. However, the conventionally decomposed material basis images may encounter severe image…

Spectral photon-counting X-ray CT (sCT) opens up new possibilities for the quantitative measurement of materials in an object, compared to conventional energy-integrating CT or dual energy CT. However, achieving reliable and accurate…

Image and Video Processing · Electrical Eng. & Systems 2020-07-15 Bingqing Xie , Pei Niu , Ting Su , Valérie Kaftandjian , Loic Boussel , Philippe Douek Feng Yang , Philippe Duvauchelle , Yuemin Zhu

X-ray computed tomography (CT) in PET/CT is commonly operated with a single energy, resulting in a limitation of lacking tissue composition information. Dual-energy (DE) spectral CT enables material decomposition by using two different…

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

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