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Spectral computed tomography based on a photon-counting detector (PCD) attracts more and more attentions since it has the capability to provide more accurate identification and quantitative analysis for biomedical materials. The limited…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Xiaodong Guo , Longhui Li , Dingyue Chang , Peng He , Peng Feng , Hengyong Yu , Weiwen Wu

As photon counting detectors are being explored for medical and industrial imaging applications, there is a critical need to understand spectral characteristics of scattered x-ray photons. Scattered radiation is detrimental to x-ray imaging…

Medical Physics · Physics 2022-12-14 Cale E. Lewis , Mini Das

Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…

The transmission matrix (TM) is a representation to describe the light scattering process through a scattering medium. The degree of control elements in TM is correlated with the capacity of evaluating enormous equations with tremendous…

Optics · Physics 2020-11-25 Shu Guo , Hao Zhang , Wenxue Li , Lin Pang

Computed Tomography (CT) imaging is one of the most influential diagnostic methods. In clinical reconstruction, an effective energy is used instead of total X-ray spectrum. This approximation causes an accuracy decline. To increase the…

Emerging Technologies · Computer Science 2018-07-25 Neda Gholami , Mohammad Mahdi Dehshibi , Mahmood Fazlali , Antonio Rueda-Toicen , Hector Zenil , Andrew Adamatzky

X-ray spectral fitting of astronomical sources requires convolving the intrinsic spectrum or model with the instrumental response. Standard forward modeling techniques have proven success in recovering the underlying physical parameters in…

Instrumentation and Methods for Astrophysics · Physics 2021-05-21 Carter Lee Rhea , Julie Hlavacek-Larrondo , Ralph Kraft , Akos Bogdan , Rudy Geelen

Quantitative estimation of contrast agent concentration is made possible by spectral CT and material decomposition. There are several approaches to modulate the sensitivity of the imaging system to obtain the different spectral channels…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Grace Gang , Eleni Liapi , Peter Noel , J. Webster Stayman

Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…

Medical Physics · Physics 2020-10-17 Matthew Tivnan , Wenying Wang , J. Webster Stayman

Computed tomography is a method for synthesizing volumetric or cross-sectional images of an object from a collection of projections. Popular reconstruction methods for computed tomography are based on idealized models and assumptions that…

Numerical Analysis · Mathematics 2022-03-03 Frederik H. Pedersen , Jakob S. Jørgensen , Martin S. Andersen

Spectral CT is an emerging modality that uses a data acquisition scheme with varied spectral responses to provide enhanced material discrimination in addition to the structural information of conventional CT. Existing clinical and…

Medical Physics · Physics 2020-10-16 Matthew Tivnan , Wenying Wang , Steven Tilley , Jeffrey H. Siewerdsen , J. Webster Stayman

For single source helical Computed Tomography (CT), both Filtered-Back Projection (FBP) and statistical iterative reconstruction have been investigated. However for dual source CT with flying focal spot (DS-FFS CT), statistical iterative…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Xiao Wang , Robert D. MacDougall , Peng Chen , Charles A. Bouman , Simon K. Warfield

In this work we discuss the known algorithms for linear colour segmentation based on a physical approach and propose a new modification of segmentation algorithm. This algorithm is based on a region adjacency graph framework without a…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Anna Smagina , Valentina Bozhkova , Sergey Gladilin , Dmitry Nikolaev

One of the advantages of spectral computed tomography (CT) is it can achieve accurate material components using the material decomposition methods. The image-based material decomposition is a common method to obtain specific material…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Weiwen Wu , Peijun Chen , Vince Vardhanabhuti , Weifei Wu , Hengyong Yu

X-ray interaction with matter is an energy-dependent process that is contingent on the atomic structure of the constituent material elements. The most advanced models to capture this relationship currently rely on Monte Carlo (MC)…

Machine Learning · Computer Science 2023-07-11 Raziye Kubra Kumrular , Thomas Blumensath

X-ray computed tomography (XCT) is an important tool for high-resolution non-destructive characterization of additively-manufactured metal components. XCT reconstructions of metal components may have beam hardening artifacts such as cupping…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Obaidullah Rahman , Singanallur V. Venkatakrishnan , Luke Scime , Paul Brackman , Curtis Frederick , Ryan Dehoff , Vincent Paquit , Amirkoushyar Ziabari

Dual-energy computed tomography (DECT) is of great significance for clinical practice due to its huge potential to provide material-specific information. However, DECT scanners are usually more expensive than standard single-energy CT…

Medical Physics · Physics 2020-06-02 Tianling Lyu , Zhan Wu , Yikun Zhang , Yang Chen , Lei Xing , Wei Zhao

X-ray cone-beam computed tomography (CT) has the notable features such as high efficiency and precision, and is widely used in the fields of medical imaging and industrial non-destructive testing, but the inherent imaging degradation…

Optics · Physics 2015-06-19 Hua Zhang , Kuidong Huang , Yikai Shi , Zhe Xu

Objective: In this work, we propose a framework for differentiable forward and back-projector that enables scalable, accurate, and memory-efficient gradient computation for rigid motion estimation tasks. Methods: Unlike existing approaches…

Medical Physics · Physics 2025-12-16 Xiao Jiang , Xin Wang , Ali Uneri , Wojciech B. Zbijewski , J. Webster Stayman

Metal objects pose a significant challenge in cone-beam computed tomography, as their strong and energy-dependent X-ray attenuation leads to inconsistent projections and severe streaking and shading artifacts in reconstructed images. These…

In computed tomography (CT), the forward model consists of a linear Radon transform followed by an exponential nonlinearity based on the attenuation of light according to the Beer-Lambert Law. Conventional reconstruction often involves…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Sara Fridovich-Keil , Fabrizio Valdivia , Gordon Wetzstein , Benjamin Recht , Mahdi Soltanolkotabi