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Computer-Aided Drug Discovery research has proven to be a promising direction in drug discovery. In recent years, Deep Learning approaches have been applied to problems in the domain such as Drug-Target Interaction Prediction and have shown…

Machine Learning · Computer Science 2020-04-28 Brighter Agyemang , Wei-Ping Wu , Michael Y. Kpiebaareh , Ebenezer Nanor

While deep neural networks (DNN) have become an effective computational tool, the prediction results are often criticized by the lack of interpretability, which is essential in many real-world applications such as health informatics.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Mengnan Du , Ninghao Liu , Qingquan Song , Xia Hu

Most uses of machine learning today involve training a model from scratch for a particular task, or sometimes starting with a model pretrained on a related task and then fine-tuning on a downstream task. Both approaches offer limited…

Machine Learning · Computer Science 2022-05-26 Andrea Gesmundo , Jeff Dean

The lack of well-structured metadata annotations complicates there-usability and interpretation of the growing amount of publicly available RNA expression data. The machine learning-based prediction of metadata(data augmentation) can…

Machine Learning · Computer Science 2019-09-27 Jelena Fiosina , Maksims Fiosins , Stefan Bonn

In this work we present a novel end-to-end framework for tracking and classifying a robot's surroundings in complex, dynamic and only partially observable real-world environments. The approach deploys a recurrent neural network to filter an…

Machine Learning · Computer Science 2016-04-20 Peter Ondruska , Julie Dequaire , Dominic Zeng Wang , Ingmar Posner

The research addresses sensor task management for radar systems, focusing on efficiently searching and tracking multiple targets using reinforcement learning. The approach develops a 3D simulation environment with an active electronically…

Machine Learning · Computer Science 2025-02-20 Jan-Hendrik Ewers , David Cormack , Joe Gibbs , David Anderson

Deep learning techniques are increasingly applied to scientific problems, where the precision of networks is crucial. Despite being deemed as universal function approximators, neural networks, in practice, struggle to reduce the prediction…

Machine Learning · Computer Science 2023-07-19 Yongji Wang , Ching-Yao Lai

Many techniques have been developed, such as model compression, to make Deep Neural Networks (DNNs) inference more efficiently. Nevertheless, DNNs still lack excellent run-time dynamic inference capability to enable users trade-off accuracy…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 Li Yang , Zhezhi He , Yu Cao , Deliang Fan

Click-Through Rate prediction (CTR) is a crucial task in recommender systems, and it gained considerable attention in the past few years. The primary purpose of recent research emphasizes obtaining meaningful and powerful representations…

Information Retrieval · Computer Science 2022-10-26 Shereen Elsayed , Lars Schmidt-Thieme

We investigate sequence machine learning techniques on raw radio signal time-series data. By applying deep recurrent neural networks we learn to discriminate between several application layer traffic types on top of a constant envelope…

Machine Learning · Computer Science 2016-10-04 Timothy J. O'Shea , Seth Hitefield , Johnathan Corgan

Knowledge tracing---where a machine models the knowledge of a student as they interact with coursework---is a well established problem in computer supported education. Though effectively modeling student knowledge would have high…

Artificial Intelligence · Computer Science 2015-06-22 Chris Piech , Jonathan Spencer , Jonathan Huang , Surya Ganguli , Mehran Sahami , Leonidas Guibas , Jascha Sohl-Dickstein

We developed an online database, ExprTargetDB, of human miRNA targets predicted by an approach that integrates gene expression profiling into a broader framework involving important features of miRNA target site predictions.

Quantitative Methods · Quantitative Biology 2013-08-09 Eric R. Gamazon , Hae-Kyung Im , Shiwei Duan , Yves A. Lussier , Nancy J. Cox , M. Eileen Dolan , Wei Zhang

We present a novel end-to-end deep learning-based adaptation control algorithm for frequency-domain adaptive system identification. The proposed method exploits a deep neural network to map observed signal features to corresponding…

Audio and Speech Processing · Electrical Eng. & Systems 2022-03-07 Thomas Haubner , Andreas Brendel , Walter Kellermann

MicroRNAs (miRs) are robust regulators of gene expression, implicated in most biological processes. microRNAs predominantly downregulate the expression of genes post-transcriptionally and each miR is predicted to target several hundred…

Deep neural networks have shown promising results for various clinical prediction tasks such as diagnosis, mortality prediction, predicting duration of stay in hospital, etc. However, training deep networks -- such as those based on…

Machine Learning · Computer Science 2018-07-06 Priyanka Gupta , Pankaj Malhotra , Lovekesh Vig , Gautam Shroff

Deep neural networks are powerful tools for solving nonlinear problems in science and engineering, but training highly accurate models becomes challenging as problem complexity increases. Non-convex optimization and sensitivity to…

Machine Learning · Computer Science 2026-04-20 Ethan Mulle , Wei Kang , Qi Gong

As high-throughput biological sequencing becomes faster and cheaper, the need to extract useful information from sequencing becomes ever more paramount, often limited by low-throughput experimental characterizations. For proteins, accurate…

Quantitative Methods · Quantitative Biology 2017-01-31 Xueliang Liu

The real-time assessment of complex motor skills presents a challenge in fields such as surgical training and rehabilitation. Recent advancements in neuroimaging, particularly functional near-infrared spectroscopy (fNIRS), have enabled…

Signal Processing · Electrical Eng. & Systems 2025-04-08 Aseem Subedi , Rahul , Lora Cavuoto , Steven Schwaitzberg , Matthew Hackett , Jack Norfleet , Suvranu De

It is an effective way that improves the performance of the existing Automatic Speech Recognition (ASR) systems by retraining with more and more new training data in the target domain. Recently, Deep Neural Network (DNN) has become a…

Sound · Computer Science 2019-04-18 Jiabin Xue , Jiqing Han , Tieran Zheng , Jiaxing Guo , Boyong Wu

A novel hierarchical Deep Neural Network (DNN) model is presented to address the task of end-to-end driving. The model consists of a master classifier network which determines the driving task required from an input stereo image and directs…

Machine Learning · Computer Science 2020-12-03 Jose Solomon , Francois Charette