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We propose a novel method for topological analysis of unweighted graphs which is based on \textit{persistent homology}. The proposed method maps the input graph to a complete weighted graph where the weighting function maps each edge to a…

Algebraic Topology · Mathematics 2020-07-31 Padraig Corcoran

Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

Alterations in nuclear morphology are useful adjuncts and even diagnostic tools used by pathologists in the diagnosis and grading of many tumors, particularly malignant tumors. Large datasets such as TCGA and the Human Protein Atlas, in…

Quantitative Methods · Quantitative Biology 2023-02-06 Mohammad Shifat E Rabbi , Natasha Ironside , John A Ozolek , Rajendra Singh , Liron Pantanowitz , Gustavo K Rohde

We propose a novel and efficient algorithm to model high-level topological structures of neuronal fibers. Tractography constructs complex neuronal fibers in three dimensions that exhibit the geometry of white matter pathways in the brain.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-04 S. Shailja , Angela Zhang , B. S. Manjunath

The multi-modal nature of many vision problems calls for neural network architectures that can perform multiple tasks concurrently. Typically, such architectures have been handcrafted in the literature. However, given the size and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 David Bruggemann , Menelaos Kanakis , Stamatios Georgoulis , Luc Van Gool

Neurodegeneration affects cortical gray matter leading to loss of cortical mantle volume. As a result of such volume loss, the geometrical arrangement of the regions on the cortical surface is expected to be altered in comparison to healthy…

Neurons and Cognition · Quantitative Biology 2016-11-16 Amanmeet Garg , Donghuan Lu , Karteek Popuri , Mirza Faisal Beg

The application of network techniques to the analysis of neural data has greatly improved our ability to quantify and describe these rich interacting systems. Among many important contributions, networks have proven useful in identifying…

Quantitative Methods · Quantitative Biology 2018-06-14 Ann E. Sizemore , Jennifer Phillips-Cremins , Robert Ghrist , Danielle S. Bassett

We construct algorithms and topological invariants that allow us to distinguish the topological type of a surface, as well as functions and vector fields for their topological equivalence. In the first part we discus the main structures…

Dynamical Systems · Mathematics 2025-01-28 Alexandr Prishlyak

Despite significant advances in the field of deep learning in applications to various fields, explaining the inner processes of deep learning models remains an important and open question. The purpose of this article is to describe and…

Machine Learning · Computer Science 2022-04-20 German Magai , Anton Ayzenberg

Humans have an exquisite sense of touch which robotic and prosthetic systems aim to recreate. We developed algorithms to create neuron-like (neuromorphic) spiking representations of texture that are invariant to the scanning speed and…

Persistent homology tracks topological features across geometric scales, encoding birth and death of cycles as barcodes. We develop a complementary theory where the filtration parameter is algebraic precision rather than geometric scale.…

Algebraic Topology · Mathematics 2025-11-04 Robert Ghrist , Cassie Ding

Branched structures that evolve over time critically determine the function of various natural and engineered systems, including growing vasculature, neural arborization, pulmonary networks such as lungs, river basins, power distribution…

Statistical Mechanics · Physics 2026-03-04 Fabian H. Kreten , Ludger Santen , Reza Shaebani

The coding mechanism of sensory memory on the neuron scale is one of the most important questions in neuroscience. We have put forward a quantitative neural network model, which is self organized, self similar, and self adaptive, just like…

Neural and Evolutionary Computing · Computer Science 2014-06-26 Peilei Liu , Ting Wang

Understanding how the brain represents and processes information is crucial for advancing neuroscience and artificial intelligence. Representational similarity analysis (RSA) has been instrumental in characterizing neural representations,…

Neurons and Cognition · Quantitative Biology 2024-08-23 Baihan Lin

This work introduces a novel framework for testing topological variability in weighted networks by combining Hodge decomposition with Wasserstein variance minimization. Traditional approaches that analyze raw edge weights are susceptible to…

Quantitative Methods · Quantitative Biology 2025-11-18 Sixtus Dakurah

Topological data analysis (TDA) is a rising branch in modern applied mathematics. It extracts topological structures as features of a given space and uses these features to analyze digital data. Persistent homology, one of the central tools…

Algebraic Topology · Mathematics 2025-05-26 Chuan-Shen Hu

The learnability of different neural architectures can be characterized directly by computable measures of data complexity. In this paper, we reframe the problem of architecture selection as understanding how data determines the most…

Machine Learning · Computer Science 2018-02-14 William H. Guss , Ruslan Salakhutdinov

Persistence diagrams (PDs), often characterized as sets of death and birth of homology class, have been known for providing a topological representation of a graph structure, which is often useful in machine learning tasks. Prior works rely…

Machine Learning · Computer Science 2022-09-29 Chau Pham , Trung Dang , Peter Chin

Long lived topological features are distinguished from short lived ones (considered as topological noise) in simplicial complexes constructed from complex networks. A new topological invariant, persistent homology, is determined and…

Mathematical Physics · Physics 2009-11-13 Danijela Horak , Slobodan Maletic , Milan Rajkovic

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund