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Clinical prognostic models derived from largescale healthcare data can inform critical diagnostic and therapeutic decisions. To enable off-theshelf usage of machine learning (ML) in prognostic research, we developed AUTOPROGNOSIS: a system…

Machine Learning · Computer Science 2018-02-21 Ahmed M. Alaa , Mihaela van der Schaar

Atom probe tomography (APT) is a valuable near-atomic scale imaging technique, which yields mass spectrographic data. Experimental correctness can often pivot on the identification of peaks within a dataset, this is a manual process where…

Atomic Physics · Physics 2017-11-21 Daniel Haley , Pyuck-Pa Choi , Dierk Raabe

Lightweight inference is critical for biomolecular structure prediction and downstream tasks, enabling efficient real-world deployment and inference-time scaling for large-scale applications. While AF3 and its variants (e.g., Protenix,…

Quantitative Methods · Quantitative Biology 2025-10-17 Bo Qiang , Chengyue Gong , Xinshi Chen , Yuxuan Zhang , Wenzhi Xiao

High peak-to-average power ratio (PAPR) is one of the main factors limiting cell coverage for cellular systems, especially in the uplink direction. Discrete Fourier transform spread orthogonal frequency-domain multiplexing (DFT-s-OFDM) with…

Information Theory · Computer Science 2024-10-15 Fabrizio Carpi , Soheil Rostami , Joonyoung Cho , Siddharth Garg , Elza Erkip , Charlie Jianzhong Zhang

Mass spectrometry provides a high-throughput approach to identify proteins in biological samples. A key step in the analysis of mass spectrometry data is to identify the peptide sequence that, most probably, gave rise to each observed…

Applications · Statistics 2013-01-14 Qunhua Li , Jimmy K. Eng , Matthew Stephens

Summary: The development of automated servers to predict the three-dimensional structure of proteins has seen much progress over the years. These servers make modeling simpler, but largely exclude users from the process. We present an…

Biomolecules · Quantitative Biology 2017-02-08 Rowan Hatherley , David K. Brown , Özlem Tastan Bishop

Masked diffusion language models (MDLMs) have recently emerged as a new paradigm in language modeling, offering flexible generation dynamics and enabling efficient parallel decoding. However, existing decoding strategies for pre-trained…

Computation and Language · Computer Science 2026-03-17 Xueyu Zhou , Yangrong Hu , Jian Huang

A plethora of protein language models have been released in recent years. Yet comparatively little work has addressed how to best sample from them to optimize desired biological properties. We fill this gap by proposing a flexible,…

Machine Learning · Computer Science 2026-05-08 Calvin McCarter , Nick Bhattacharya , Sebastian W. Ober , Hunter Elliott

This paper proposes a multi-step probabilistic forecasting framework using a single neural-network based model to generate simultaneous point and interval forecasts. Our approach ensures non-crossing prediction intervals (PIs) through a…

Machine Learning · Computer Science 2026-04-21 Worachit Amnuaypongsa , Yotsapat Suparanonrat , Pana Wanitchollakit , Jitkomut Songsiri

Understanding the principles of protein folding is a cornerstone of computational biology, with implications for drug design, bioengineering, and the understanding of fundamental biological processes. Lattice protein folding models offer a…

Disordered Systems and Neural Networks · Physics 2025-08-08 Shoummo Ahsan Khandoker , Estelle M. Inack , Mohamed Hibat-Allah

Purpose: A fast data-driven optimization approach, named bias-accelerated subset selection (BASS), is proposed for learning efficacious sampling patterns (SPs) with the purpose of reducing scan time in large-dimensional parallel MRI.…

Signal Processing · Electrical Eng. & Systems 2020-11-05 Marcelo V. W. Zibetti , Gabor T. Herman , Ravinder R. Regatte

For mass spectra acquired from cancer patients by MALDI or SELDI techniques, automated discrimination between cancer types or stages has often been implemented by machine learnings. These techniques typically generate "black-box"…

Machine Learning · Statistics 2014-10-14 Ao Kong , Robert Azencott

New hardware can substantially increase the speed and efficiency of deep neural network training. To guide the development of future hardware architectures, it is pertinent to explore the hardware and machine learning properties of…

Machine Learning · Computer Science 2021-04-13 Atli Kosson , Vitaliy Chiley , Abhinav Venigalla , Joel Hestness , Urs Köster

This paper presents an adaptive sampling algorithm tailored for the optimization of parametrized dynamical systems using projection-based model order reduction. Unlike classical sampling strategies, this framework does not aim for a small…

Computational Engineering, Finance, and Science · Computer Science 2026-02-27 Marcel Warzecha , Sebastian Resch-Schopper , Gerhard Müller

An insufficient number of training samples is a common problem in neural network applications. While data augmentation methods require at least a minimum number of samples, we propose a novel, rendering-based pipeline for synthesizing…

Computer Vision and Pattern Recognition · Computer Science 2022-09-30 Andreas Spruck , Maximilane Gruber , Anatol Maier , Denise Moussa , Jürgen Seiler , Christian Riess , André Kaup

Anti-spoofing is the task of speech authentication. That is, identifying genuine human speech compared to spoofed speech. The main focus of this paper is to suggest new representations for genuine and spoofed speech, based on the…

Audio and Speech Processing · Electrical Eng. & Systems 2022-10-28 Matan Karo , Arie Yeredor , Itshak Lapidot

Microbial identification is a central issue in microbiology, in particular in the fields of infectious diseases diagnosis and industrial quality control. The concept of species is tightly linked to the concept of biological and clinical…

Machine Learning · Statistics 2015-06-25 Kévin Vervier , Pierre Mahé , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Selective Laser Melting (SLM) is a powder-bed additive manufacturing technique whose part quality depends critically on feedstock morphology. However, conventional powder characterization methods are low-throughput and qualitative, failing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Emmanuel Akeweje , Conall Kirk , Chi-Wai Chan , Denis Dowling , Mimi Zhang

Anatomic tracer studies are critical for validating and improving diffusion MRI (dMRI) tractography. However, large-scale analysis of data from such studies is hampered by the labor-intensive process of annotating fiber bundles manually on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Kyriaki-Margarita Bintsi , Yaël Balbastre , Jingjing Wu , Julia F. Lehman , Suzanne N. Haber , Anastasia Yendiki

Machine learning interatomic potentials (MLIPs) have become powerful tools to extend molecular simulations beyond the limits of quantum methods, offering near-quantum accuracy at much lower computational cost. Yet, developing reliable MLIPs…

Materials Science · Physics 2025-12-30 Adam Lahouari , Jutta Rogal , Mark E. Tuckerman