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Data stewards and analysts can promote transparent and trustworthy science and policy-making by facilitating assessments of the sensitivity of published results to alternate analysis choices. For example, researchers may want to assess…

Methodology · Statistics 2023-08-24 Chengxin Yang , Jerome P. Reiter

Linear regression is arguably the most fundamental statistical model; however, the validity of its use in randomized clinical trials, despite being common practice, has never been crystal clear, particularly when stratified or…

Methodology · Statistics 2023-02-14 Wei Ma , Fuyi Tu , Hanzhong Liu

We consider vertical logistic regression (VLR) trained with mini-batch gradient descent -- a setting which has attracted growing interest among industries and proven to be useful in a wide range of applications including finance and medical…

Cryptography and Security · Computer Science 2022-07-20 Yuzheng Hu , Tianle Cai , Jinyong Shan , Shange Tang , Chaochao Cai , Ethan Song , Bo Li , Dawn Song

In recent years, machine learning techniques are widely used in numerous applications, such as weather forecast, financial data analysis, spam filtering, and medical prediction. In the meantime, massive data generated from multiple sources…

Cryptography and Security · Computer Science 2018-10-08 Wei Du , Ang Li , Qinghua Li

In many contexts, we have access to aggregate data, but individual level data is unavailable. For example, medical studies sometimes report only aggregate statistics about disease prevalence because of privacy concerns. Even so, many a time…

Machine Learning · Computer Science 2018-09-18 Sanket Tavarageri , Nag Mani , Anand Ramasubramanian , Jaskiran Kalsi

Two different approaches to analysis of data from diagnostic biomarker studies are commonly employed. Logistic regression is used to fit models for probability of disease given marker values, while ROC curves and risk distributions are used…

Applications · Statistics 2013-12-02 Ying Huang , Margaret S. Pepe , Ziding Feng

We study the statistical complexity of private linear regression under an unknown, potentially ill-conditioned covariate distribution. Somewhat surprisingly, under privacy constraints the intrinsic complexity is \emph{not} captured by the…

Machine Learning · Computer Science 2025-11-06 Fan Chen , Jiachun Li , Alexander Rakhlin , David Simchi-Levi

In survival analysis, regression models are used to understand the effects of explanatory variables (e.g., age, sex, weight, etc.) to the survival probability. However, for sensitive survival data such as medical data, there are serious…

Machine Learning · Computer Science 2017-08-28 Thông T. Nguyên , Siu Cheung Hui

We develop an improvement to conditional logistic regression (CLR) in the setting where the parameter of interest is the additive effect of binary treatment effect on log-odds of the positive level in the binary response. Our improvement is…

Methodology · Statistics 2026-03-03 Jacob Tennenbaum , Adam Kapelner

Usage data of a group of users distributed across a number of categories, such as songs, movies, webpages, links, regular household products, mobile apps, games, etc. can be ultra-high dimensional and massive in size. More often this kind…

Machine Learning · Computer Science 2023-05-30 Animesh Mitra , Saswata Sahoo , Soumyabrata Dey

The grade of membership model is a flexible latent variable model for analyzing multivariate categorical data through individual-level mixed membership scores. In many modern applications, auxiliary covariates are collected alongside…

Methodology · Statistics 2026-01-27 Zhiyu Xu , Yuqi Gu

We propose a generalisation of the logistic regression model, that aims to account for non-linear main effects and complex interactions, while keeping the model inherently explainable. This is obtained by starting with log-odds that are…

Methodology · Statistics 2024-10-14 Ingrid Hobæk Haff , Simon Boge Brant , Haakon Bakka

In medical, social, and behavioral research we often encounter datasets with a multilevel structure and multiple correlated dependent variables. These data are frequently collected from a study population that distinguishes several…

Methodology · Statistics 2023-12-18 Xynthia Kavelaars , Joris Mulder , Maurits Kaptein

Logistic regression is a common classification method in supervised learning. Surprisingly, there are very few solutions for performing logistic regression with missing values in the covariates. We suggest a complete approach based on a…

Methodology · Statistics 2019-08-09 Wei Jiang , Julie Josse , Marc Lavielle , TraumaBase Group

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target…

Methodology · Statistics 2022-11-24 Jaime Roquero Gimenez , Dominik Rothenhäusler

This review provides a systematic overview of methods that combine covariate-based clustering of observational units (patients) with outcome models for clinical studies. We distinguish between informed-cluster models, where the outcome…

Online collaborative medical prediction platforms offer convenience and real-time feedback by leveraging massive electronic health records. However, growing concerns about privacy and low prediction quality can deter patient participation…

Machine Learning · Computer Science 2025-07-16 Shao-Bo Lin , Xiaotong Liu , Yao Wang

Differential privacy is the leading mathematical framework for privacy protection, providing a probabilistic guarantee that safeguards individuals' private information when publishing statistics from a dataset. This guarantee is achieved by…

Methodology · Statistics 2025-08-19 Yuki Ohnishi , Jordan Awan

Measurement error arises through a variety of mechanisms. A rich literature exists on the bias introduced by covariate measurement error and on methods of analysis to address this bias. By comparison, less attention has been given to errors…

Methodology · Statistics 2018-11-27 Pamela Shaw , Jiwei He , Bryan Shepherd

The development of deep learning techniques is a leading field applied to cases in which medical data is used, particularly in cases of image diagnosis. This type of data has privacy and legal restrictions that in many cases prevent it from…

Machine Learning · Computer Science 2025-01-28 Judith Sáinz-Pardo Díaz , Álvaro López García