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We propose a new problem formulation which is similar to, but more informative than, the binary multiple-instance learning problem. In this setting, we are given groups of instances (described by feature vectors) along with estimates of the…

Machine Learning · Computer Science 2012-07-09 Hendrik Kuck , Nando de Freitas

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Novanto Yudistira , Muthu Subash Kavitha , Jeny Rajan , Takio Kurita

Annotating multi-class instances is a crucial task in the field of machine learning. Unfortunately, identifying the correct class label from a long sequence of candidate labels is time-consuming and laborious. To alleviate this problem, we…

Machine Learning · Computer Science 2025-12-05 Meng Wei , Zhongnian Li , Yong Zhou , Qiaoyu Guo , Xinzheng Xu

Positive--Unlabeled (PU) learning considers settings in which only positive and unlabeled data are available, while negatives are missing or left unlabeled. This situation is common in real applications where annotating reliable negatives…

Machine Learning · Computer Science 2025-10-30 Miao Zhang , Junpeng Li , Changchun Hua , Yana Yang

We propose to formulate multi-label learning as a estimation of class distribution in a non-linear embedding space, where for each label, its positive data embeddings and negative data embeddings distribute compactly to form a positive…

Machine Learning · Computer Science 2020-12-18 Zhuo Yang , Yufei Han , Guoxian Yu , Qiang Yang , Xiangliang Zhang

Fuzzy logic is a powerful tool to model knowledge uncertainty, measurements imprecision, and vagueness. However, there is another type of vagueness that arises when data have multiple forms of expression that fuzzy logic does not address…

Neural and Evolutionary Computing · Computer Science 2016-10-18 Amine Ben Khalifa , Hichem Frigui

In this work, we introduce a new information-theoretic perspective on Multiple Instance Learning (MIL) for parameter estimation with i.i.d. data, and show that MIL can outperform single-instance learners in low-signal regimes. Prior work…

Machine Learning · Computer Science 2025-12-03 Atakan Azakli , Bernd Stelzer

Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda

It is critical and meaningful to make image classification since it can help human in image retrieval and recognition, object detection, etc. In this paper, three-sides efforts are made to accomplish the task. First, visual features with…

Computer Vision and Pattern Recognition · Computer Science 2016-10-24 Dewei Li , Yingjie Tian

Learning accurate object detectors often requires large-scale training data with precise object bounding boxes. However, labeling such data is expensive and time-consuming. As the crowd-sourcing labeling process and the ambiguities of the…

Computer Vision and Pattern Recognition · Computer Science 2022-07-21 Chengxin Liu , Kewei Wang , Hao Lu , Zhiguo Cao , Ziming Zhang

Multiple instance learning (MIL) is a robust paradigm for whole-slide pathological image (WSI) analysis, processing gigapixel-resolution images with slide-level labels. As pioneering efforts, attention-based MIL (ABMIL) and its variants are…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Linghan Cai , Shenjin Huang , Ye Zhang , Jinpeng Lu , Yongbing Zhang

Multiple Instance Learning (MIL) is a popular weakly-supervised method for various applications, with a particular interest in histological whole slide image (WSI) classification. Due to the gigapixel resolution of WSI, applications of MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Zhangsihao Yang , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Since the labelling for the positive images/videos is ambiguous in weakly supervised segment annotation, negative mining based methods that only use the intra-class information emerge. In these methods, negative instances are utilized to…

Computer Vision and Pattern Recognition · Computer Science 2018-12-18 Liantao Wang , Qingwu Li , Jianfeng Lu

This work presents a new strategy for multi-class classification that requires no class-specific labels, but instead leverages pairwise similarity between examples, which is a weaker form of annotation. The proposed method, meta…

Machine Learning · Computer Science 2019-01-04 Yen-Chang Hsu , Zhaoyang Lv , Joel Schlosser , Phillip Odom , Zsolt Kira

The dynamic environment of laboratories and clinics, with streams of data arriving on a daily basis, requires regular updates of trained machine learning models for consistent performance. Continual learning is supposed to help train models…

Machine Learning · Computer Science 2025-08-12 Zahra Ebrahimi , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

We consider the problem of learning a binary classifier from a training set of positive and unlabeled examples, both in the inductive and in the transductive setting. This problem, often referred to as \emph{PU learning}, differs from the…

Machine Learning · Statistics 2010-10-06 Fantine Mordelet , Jean-Philippe Vert

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn

Motivated by applications in protein function prediction, we consider a challenging supervised classification setting in which positive labels are scarce and there are no explicit negative labels. The learning algorithm must thus select…

Machine Learning · Computer Science 2019-01-28 Marco Frasca , Nicolò Cesa-Bianchi
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