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Whole Slide Image (WSI) classification remains a challenge due to their extremely high resolution and the absence of fine-grained labels. Presently, WSI classification is usually regarded as a Multiple Instance Learning (MIL) problem when…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Hongyi Wang , Luyang Luo , Fang Wang , Ruofeng Tong , Yen-Wei Chen , Hongjie Hu , Lanfen Lin , Hao Chen

Multiple Instance Learning (MIL) has advanced WSI analysis but struggles with the complexity and heterogeneity of WSIs. Existing MIL methods face challenges in aggregating diverse patch information into robust WSI representations. While…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Beidi Zhao , SangMook Kim , Hao Chen , Chen Zhou , Zu-hua Gao , Gang Wang , Xiaoxiao Li

The paper proposes a novel problem in multi-class Multiple-Instance Learning (MIL) called Learning from the Majority Label (LML). In LML, the majority class of instances in a bag is assigned as the bag's label. LML aims to classify…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Kaito Shiku , Shinnosuke Matsuo , Daiki Suehiro , Ryoma Bise

Multi-label learning (MLL) requires comprehensive multi-semantic annotations that is hard to fully obtain, thus often resulting in missing labels scenarios. In this paper, we investigate Single Positive Multi-label Learning (SPML), where…

Machine Learning · Computer Science 2024-05-07 Yanxi Chen , Chunxiao Li , Xinyang Dai , Jinhuan Li , Weiyu Sun , Yiming Wang , Renyuan Zhang , Tinghe Zhang , Bo Wang

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

A multiple instance dictionary learning method using functions of multiple instances (DL-FUMI) is proposed to address target detection and two-class classification problems with inaccurate training labels. Given inaccurate training labels,…

Computer Vision and Pattern Recognition · Computer Science 2016-08-05 Changzhe Jiao , Alina Zare

Multiple Instance Learning (MIL) offers a natural solution for settings where only coarse, bag-level labels are available, without having access to instance-level annotations. This is usually the case in digital pathology, which consists of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Andreas Lolos , Stergios Christodoulidis , Aris L. Moustakas , Jose Dolz , Maria Vakalopoulou

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Histopathology image analysis can be considered as a Multiple instance learning (MIL) problem, where the whole slide histopathology image (WSI) is regarded as a bag of instances (i.e, patches) and the task is to predict a single class label…

Computer Vision and Pattern Recognition · Computer Science 2019-06-28 Meng Li , Lin Wu , Arnold Wiliem , Kun Zhao , Teng Zhang , Brian C. Lovell

Multiple Instance Learning is a form of weakly supervised learning in which the data is arranged in sets of instances called bags with one label assigned per bag. The bag level class prediction is derived from the multiple instances through…

Computer Vision and Pattern Recognition · Computer Science 2020-08-25 Jacob Gildenblat , Ido Ben-Shaul , Zvi Lapp , Eldad Klaiman

The paper proposes a novel multi-class Multiple-Instance Learning (MIL) problem called Learning from Majority Label (LML). In LML, the majority class of instances in a bag is assigned as the bag-level label. The goal of LML is to train a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Shiku Kaito , Shinnosuke Matsuo , Daiki Suehiro , Ryoma Bise

In multiple instance learning, objects are sets (bags) of feature vectors (instances) rather than individual feature vectors. In this paper we address the problem of how these bags can best be represented. Two standard approaches are to use…

Machine Learning · Statistics 2016-07-12 Veronika Cheplygina , David M. J. Tax , Marco Loog

In learning from aggregate labels, the training data consists of sets or "bags" of feature-vectors (instances) along with an aggregate label for each bag derived from the (usually {0,1}-valued) labels of its instances. In learning from…

Machine Learning · Computer Science 2024-11-12 Yukti Makhija , Rishi Saket

A new multi-attention based method for solving the MIL problem (MAMIL), which takes into account the neighboring patches or instances of each analyzed patch in a bag, is proposed. In the method, one of the attention modules takes into…

Machine Learning · Computer Science 2021-12-14 Andrei V. Konstantinov , Lev V. Utkin

This paper presents a novel approach to Single-Positive Multi-label Learning. In general multi-label learning, a model learns to predict multiple labels or categories for a single input image. This is in contrast with standard multi-class…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Xin Xing , Zhexiao Xiong , Abby Stylianou , Srikumar Sastry , Liyu Gong , Nathan Jacobs

Multiple instance learning (MIL) is often used in medical imaging to classify high-resolution 2D images by processing patches or classify 3D volumes by processing slices. However, conventional MIL approaches treat instances separately,…

Machine Learning · Computer Science 2025-11-13 Ethan Harvey , Dennis Johan Loevlie , Michael C. Hughes

Weak-label learning is a challenging task that requires learning from data "bags" containing positive and negative instances, but only the bag labels are known. The pool of negative instances is usually larger than positive instances, thus…

Machine Learning · Computer Science 2023-09-26 Ankit Shah , Fuyu Tang , Zelin Ye , Rita Singh , Bhiksha Raj

Learning from multiple annotators aims to induce a high-quality classifier from training instances, where each of them is associated with a set of possibly noisy labels provided by multiple annotators under the influence of their varying…

Machine Learning · Computer Science 2021-06-30 Jingzheng Li , Hailong Sun , Jiyi Li , Zhijun Chen , Renshuai Tao , Yufei Ge

In this paper, we propose an extension to an existing algorithm (instance-MIR) which tackles the multiple instance regression (MIR) problem, also known as distribution regression. The MIR setting arises when the data is a collection of…

Machine Learning · Statistics 2019-08-20 Thomas Uriot
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