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Sudden transitions in the state of a system are often undesirable in natural and human-made systems. Such transitions under fast variation of system parameters are called rate-induced tipping. We experimentally demonstrate rate-induced…

Applied Physics · Physics 2022-09-15 Induja Pavithran , P. R. Midhun , R. I. Sujith

This paper investigates the different behaviors of the process equation and parameters of their occurrences. The process equation is a multistable one dimensional map with nonlinear feedback and can show various behaviors such as period…

Genetically encoded regulatory circuits control biological function. A major focus of systems biology is to understand these circuits by establishing the relationship between specific structures and functions. Of special interest are…

Molecular Networks · Quantitative Biology 2017-08-17 Ruben Perez-Carrasco , Chris P. Barnes , Yolanda Schaerli , Mark Isalan , James Briscoe , Karen M. Page

In this work we identify and investigate a novel bifurcation in conserved systems. This secondary bifurcation stops active phase separation in its nonlinear regime. It is then either replaced by an extended, system-filling, spatially…

Pattern Formation and Solitons · Physics 2022-02-22 Frederik J. Thomsen , Lisa Rapp , Fabian Bergmann , Walter Zimmermann

Many processes in chemistry, physics, and biology involve rare events in which the system escapes from a metastable state by surmounting an activation barrier. Examples range from chemical reactions, protein folding, and nucleation events…

Chemical Physics · Physics 2020-10-07 Niels Zijlstra , Daniel Nettels , Rohit Satija , Dmitrii E. Makarov , Benjamin Schuler

Coupling a quantum many-body system to a cavity can create bifurcation points in its phase diagram, where the ground state makes sudden switchings between different phases. Here we study the dynamical quantum phase transition of a…

Quantum Physics · Physics 2016-05-10 Lin Tian

In epidemiological modelling, dynamics on networks, and in particular adaptive and heterogeneous networks have recently received much interest. Here we present a detailed analysis of a previously proposed model that combines heterogeneity…

Physics and Society · Physics 2016-09-21 Hui Yang , Tim Rogers , Thilo Gross

There exists a variety of physically interesting situations described by continuous maps that are nondifferentiable on some surface in phase space. Such systems exhibit novel types of bifurcations in which multiple coexisting attractors can…

chao-dyn · Physics 2009-10-31 Mitrajit Dutta , Helena E. Nusse , Edward Ott , James A. Yorke

We study the fluctuation-activated transition process in a system of two coupled bistable oscillators, in which each oscillator is driven by one constant force and an independent Gaussian white noise. The transition pathway has been…

Statistical Mechanics · Physics 2014-08-21 Hanshuang Chen , Feng Huang , Chuansheng Shen , Gang He , Zhonghuai Hou

In this paper, dynamical systems theory and bifurcation theory are applied to investi- gate the rich dynamical behaviours observed in three simple disease models. The 2- and 3-dimensional models we investigate have arisen in previous…

Dynamical Systems · Mathematics 2015-04-22 Wenjing Zhang , Pei Yu , Lindi M. Wahl

We study a mechanism for reliable switching in biomolecular signal-transduction cascades. Steady bistable states are created by system-size cooperative effects in populations of proteins, in spite of the fact that the phosphorylation-state…

Subcellular Processes · Quantitative Biology 2015-05-30 Eric Smith , Supriya Krishnamurthy , Walter Fontana , David Krakauer

Certain cellular processes take the form of activity pulses that can be interpreted in terms of noise-driven excitable dynamics. Here we present an overview of different gene circuit architectures that exhibit excitable pulses of protein…

Molecular Networks · Quantitative Biology 2011-04-22 Pau Rué , Jordi Garcia-Ojalvo

In this paper we study how to shape temporal pulses to switch a bistable system between its stable steady states. Our motivation for pulse-based control comes from applications in synthetic biology, where it is generally difficult to…

Optimization and Control · Mathematics 2015-10-05 Aivar Sootla , Diego Oyarzun , David Angeli , Guy-Bart Stan

Model studies indicate that many climate subsystems, especially ecosystems, may be vulnerable to 'tipping': a 'catastrophic process' in which a system, driven by gradually changing external factors, abruptly transitions (or 'collapses')…

Dynamical Systems · Mathematics 2025-06-30 Dock Staal , Arjen Doelman

Noise-induced transitions between metastable fixed points in systems evolving on multiple time scales are analyzed in situations where the time scale separation gives rise to a slow manifold with bifurcation. This analysis is performed…

Statistical Mechanics · Physics 2017-10-05 Tobias Grafke , Eric Vanden-Eijnden

We investigate dynamics and bifurcations in a mathematical model that captures electrochemical experiments on arrays of microelectrodes. In isolation, each individual microelectrode is described by a one-dimensional unit with a bistable…

Adaptation and Self-Organizing Systems · Physics 2021-12-08 Munir Salman , Christian Bick , Katharina Krischer

Complex systems exhibiting critical transitions when one of their governing parameters varies are ubiquitous in nature and in engineering applications. Despite a vast literature focusing on this topic, there are few studies dealing with the…

Fluid Dynamics · Physics 2018-03-08 Giacomo Bonciolini , Dominik Ebi , Edouard Boujo , Nicolas Noiray

We perform a bifurcation analysis on an SIR model involving two pathogens that influences each other. Partial cross-immunity is assumed and coinfection is thought to be less transmittable then each of the diseases alone. The susceptible…

Dynamical Systems · Mathematics 2022-09-09 J. Andersson , V. Kozlov , V. G. Tkachev , U. Wennergren

Prokaryotic gene expression is dynamic and noisy, and can lead to phenotypic variations. Previous work has shown that the selection of such variation can be modeled through basic reaction networks described by O.D.E. displaying a bistable…

Molecular Networks · Quantitative Biology 2023-04-10 Xavier Richard , Benoît Richard , Christian Mazza , Jan Roelof van der Meer

We report a noise induced delay of bifurcation in a simple pulse-coupled neural circuit. We study the behavior of two neural oscillators, each individually governed by saddle-node dynamics, with reciprocal excitatory synaptic connections.…

Biological Physics · Physics 2007-05-23 Boris Gutkin , Tim Hely , Juergen Jost