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Light-field microscopy represents a promising solution for microscopic volumetric imaging, thanks to its capability to encode information on multiple planes in a single acquisition. This is achieved through its peculiar simultaneous capture…

Image Phase Alignment Super-Sampling (ImPASS) is a computational imaging algorithm for converting a sequence of displaced low-resolution images into a single high-resolution image. The method consists of a unique combination of Phase…

Optics · Physics 2025-09-01 James N. Caron

Low-light image enhancement (LLIE) aims to improve the illuminance of images due to insufficient light exposure. Recently, various lightweight learning-based LLIE methods have been proposed to handle the challenges of unfavorable prevailing…

Computer Vision and Pattern Recognition · Computer Science 2023-05-24 Yuantong Zhang , Baoxin Teng , Daiqin Yang , Zhenzhong Chen , Haichuan Ma , Gang Li , Wenpeng Ding

Super-resolution microscopy is crucial for imaging sub-wavelength biological structures. However, most techniques rely on nonlinear saturation or stochastic switching of emitters, limiting imaging speed and increasing phototoxicity. Here,…

Plenoptic cameras offer a cost effective solution to capture light fields by multiplexing multiple views on a single image sensor. However, the high angular resolution is achieved at the expense of reducing the spatial resolution of each…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Reuben A. Farrugia , C. Guillemot

Single-pixel imaging, originally developed in light optics, facilitates fast three-dimensional sample reconstruction, as well as probing with light wavelengths undetectable by conventional multi-pixel detectors. However, the spatial…

We propose to use intensity correlation microscopy in combination with structured illumination to image quantum emitters that exhibit antibunching with a spatial resolution reaching far beyond the Rayleigh limit. Combining intensity…

Photoluminesce (PL) spectroscopy offers excellent methods for mapping the PL decay on the nanosecond time scale. However, capturing maps of emission dynamics on the microsecond time scale can be highly time-consuming. We present a new…

Optics · Physics 2021-02-24 Jiri Junek , Karel Zidek

Fast and sensitive detector arrays enable image scanning microscopy (ISM), overcoming the trade-off between spatial resolution and signal-to-noise ratio (SNR) typical of confocal microscopy. However, current ISM approaches cannot provide…

The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…

Super Resolution (SR) plays a critical role in computer vision, particularly in medical imaging, where hardware and acquisition time constraints often result in low spatial and temporal resolution. While diffusion models have been applied…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Vishal Dubey

We propose a straightforward sample-based technique to calibrate the axial detection in 3D single molecule localization microscopy (SMLM). Using microspheres coated with fluorescent molecules, the calibration curves of PSF-shaping- or…

Imaging below the diffraction limit is always a public interest because of the restricted resolution of conventional imaging systems. To beat the limit, evanescent harmonics decaying in space must participate in the imaging process. Here,…

Optics · Physics 2019-10-02 Tie-Jun Huang , Li-Zheng Yin , Ya Shuang , Jiang-Yu Liu , Yunhua Tan , Pu-Kun Liu

We propose and experimentally demonstrate a high-efficiency single-pixel imaging (SPI) scheme by integrating time-correlated single-photon counting (TCSPC) with time-division multiplexing to acquire full-color images at extremely low light…

This study introduces SEFI (SEgmentation-Free Integration), a novel method for integrating morphological features of cell nuclei with spatial transcriptomics data. Cell segmentation poses a significant challenge in the analysis of spatial…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Eduard Chelebian , Pratiti Dasgupta , Zainalabedin Samadi , Carolina Wählby , Amjad Askary

Lensless illumination single-pixel imaging with a multicore fiber (MCF) is a computational imaging technique that enables potential endoscopic observations of biological samples at cellular scale. In this work, we show that this technique…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Olivier Leblanc , Mathias Hofer , Siddharth Sivankutty , Hervé Rigneault , Laurent Jacques

In deep tissue photoacoustic imaging, the spatial resolution is inherently limited by acoustic diffraction. Moreover, as the ultrasound attenuation increases with frequency, resolution is often traded-off for penetration depth. Here we…

A lensfree spectral light-field fusion microscopy (LSLFM) system is presented for enabling contrast- and resolution-enhanced imaging of biological specimens. LSLFM consists of a pulsed multispectral lensfree microscope for capturing…

In this paper, we propose a novel method for image fusion with a high-resolution panchromatic image and a low-resolution multispectral image at the same geographical location. The fusion is formulated as a convex optimization problem which…

Computer Vision and Pattern Recognition · Computer Science 2015-10-28 Chen Chen , Yeqing Li , Wei Liu , Junzhou Huang

Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…

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