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The movement of the infective form of the T. Cruzi parasite within the human blood is not completely understood. Video microscopy observations confirm forward motility of the protozoa and relate it to the deformation of the body,…

Biological Physics · Physics 2025-10-27 Alberto-Mario Castillo , Gabriel Villalobos

Chagas disease American trypanosomiasis is caused by a flagellated parasite: trypanosoma cruzi, transmitted by an insect of the genus Triatoma and also by blood transfusions. In Latin America the number of infected people is approximately 6…

Quantitative Methods · Quantitative Biology 2019-12-11 Miguel Vizcardo , Antonio Ravelo , Pedro Gomis

Trypanosoma cruzi and Giardia intestinalis are two human pathogens and protozoan parasites responsible for the diseases Chagas disease and giardiasis, respectively. Both diseases cause suffering and illness in several million individuals.…

Genomics · Quantitative Biology 2012-11-20 Oscar Franzén

Toxoplasma gondii is a parasitic protozoan that causes dis- seminated toxoplasmosis, a disease that afflicts roughly a third of the worlds population. Its virulence is predicated on its motility and ability to enter and exit nucleated…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Mojtaba S. Fazli , Stephen A. Vella , Silvia N. J. Moreno , Shannon Quinn

Malaria is transmitted to vertebrates via a mosquito bite, during which rod-like and crescent-shaped parasites, called sporozoites, are injected into the skin of the host. Searching for a blood capillary to penetrate, sporozoites move…

Cell Behavior · Quantitative Biology 2014-10-24 Anna Battista , Friedrich Frischknecht , Ulrich S. Schwarz

We seek to characterize the motility of mouse fibroblasts on 2D substrates. Utilizing automated tracking techniques, we find that cell trajectories are super-diffusive, where displacements scale faster than t^(1/2) in all directions. Two…

Soft Condensed Matter · Physics 2017-12-15 G Passucci , ME Brasch , JH Henderson , V Zaburdaev , ML Manning

Although the auger-like 'swimming' motility of the African trypanosome was described upon its discovery over one hundred years ago, the precise biomechanical and biophysical properties of trypanosome flagellar motion has not been…

Biological Physics · Physics 2016-09-08 D. Fry , N. Hutchings , A. Ludu

Background: Trypanosoma brucei is the causative agent of human African sleeping sickness and Nagana in cattle. In addition to being an important pathogen T. brucei has developed into a model system in cell biology. Results: Using Stable…

Quantitative Methods · Quantitative Biology 2021-08-30 Kapila Gunasekera , Daniel Wüthrich , Sophie Braga-Lagache , Manfred Heller , Torsten Ochsenreiter

We analyse mobile-immobile transport of particles that switch between the mobile and immobile phases with finite rates. Despite this seemingly simple assumption of Poissonian switching we unveil a rich transport dynamics including…

Statistical Mechanics · Physics 2022-03-28 T. Doerries , A. V. Chechkin , R. Metzler

Emerging marine infectious diseases pose a substantial threat to marine ecosystems and the conservation of their biodiversity. Compartmental models of epidemic transmission in marine sessile organisms, available only recently, are based on…

Populations and Evolution · Quantitative Biology 2022-11-03 Àlex Giménez-Romero , Federico Vazquez , Cristóbal López , Manuel A. Matías

The movement of organisms and cells can be governed by occasional long distance runs, according to an approximate L\'evy walk. For T cells migrating through chronically-infected brain tissue, runs are further interrupted by long pauses, and…

Biological Physics · Physics 2020-03-06 Gissell Estrada-Rodriguez , Heiko Gimperlein , Kevin J. Painter , Jakub Stocek

It is well established that the parasites of the genus Leishmania exhibit complex surface interactions with the sandfly vector midgut epithelium, but no prior study has considered the details of their hydrodynamics. Here, the boundary…

Biological Physics · Physics 2018-12-10 Benjamin J. Walker , Richard J. Wheeler , Kenta Ishimoto , Eamonn A. Gaffney

Quantifying how spatial disorder affects the movement of a diffusing particle or agent is fundamental to target search studies. When diffusion occurs on a network, that is on a highly disordered environment, we lack the mathematical tools…

Statistical Mechanics · Physics 2025-08-15 Daniel Marris , Chittaranjan Hens , Subrata Ghosh , Luca Giuggioli

In the recent years, MRI-driven turbulent transport has been found to depend in a significant way on fluid viscosity $\nu$ and resistivity $\eta$ through the magnetic Prandtl number $Pm=\nu/\eta$. In particular, the transport decreases with…

Solar and Stellar Astrophysics · Physics 2015-05-18 P. -Y. Longaretti , G. Lesur

Acanthamoebae are free-living protists and human pathogens, whose cellular functions and pathogenicity strongly depend on the transport of intracellular vesicles and granules through the cytosol. Using high-speed live cell imaging in…

Biological Physics · Physics 2015-07-03 J. F. Reverey , J. -H. Jeon , H. Bao , M. Leippe , R. Metzler , C. Selhuber-Unkel

Swimming eukaryotic microorganisms such as spermatozoa, algae and ciliates self-propel in viscous fluids using travelling wave-like deformations of slender appendages called flagella. Waves are predominant because Purcell's scallop theorem…

Fluid Dynamics · Physics 2020-11-18 Eric Lauga

Trypanosoma brucei (T. brucei), a single-celled parasite and natural microswimmer, is responsible for fatal sleeping sickness in infected mammals, including humans. Understanding how T. brucei interacts with fluid environments and navigates…

Soft Condensed Matter · Physics 2025-06-02 Zihan Tan , Julian I. U. Peters , Holger Stark

The motility of many parasites is critical for the infection process of their host, as exemplified by the transmission cycle of the blood fluke Schistosoma mansoni. In their human infectious stage, immature, submillimetre-scale forms of the…

Biological Physics · Physics 2016-05-16 Deepak Krishnamurthy , Georgios Katsikis , Arjun Bhargava , Manu Prakash

In the present article, we demonstrate the emergence and existence of the spiral wave chimera-like transient pattern in coupled ecological systems, composed of prey-predator patches, where the patches are connected in a three-dimensional…

Adaptation and Self-Organizing Systems · Physics 2022-08-02 Bidesh K. Bera , Srilena Kundu , Paulsamy Muruganandam , Dibakar Ghosh , M. Lakshmanan

More than half of the world's population is exposed to the risk of mosquito-borne diseases, which leads to millions of cases and hundreds of thousands of deaths every year. Analyzing this type of data is often complex and poses several…

Methodology · Statistics 2025-07-14 Jessica Pavani , Fernando Andrés Quintana
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