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The inference of networks of dependencies by Gaussian Graphical models on high-throughput data is an open issue in modern molecular biology. In this paper we provide a comparative study of three methods to obtain small sample and high…

Molecular Networks · Quantitative Biology 2022-03-02 P. F. Stifanelli , T. M. Creanza , R. Anglani , V. C. Liuzzi , S. Mukherjee , N. Ancona

The increasing availability and accessibility of numerous overhead images allows us to estimate and assess the spatial arrangement of groups of geospatial target objects, which can benefit many applications, such as traffic monitoring and…

Computer Vision and Pattern Recognition · Computer Science 2021-12-14 Weiwei Duan , Yao-Yi Chiang , Stefan Leyk , Johannes H. Uhl , Craig A. Knoblock

Randomized iterative methods, such as the Kaczmarz method and its variants, have gained growing attention due to their simplicity and efficiency in solving large-scale linear systems. Meanwhile, absolute value equations (AVE) have attracted…

Numerical Analysis · Mathematics 2025-05-13 Jiaxin Xie , Hou-Duo Qi , Deren Han

Seemingly unrelated regression is a natural framework for regressing multiple correlated responses on multiple predictors. The model is very flexible, with multiple linear regression and covariance selection models being special cases.…

Methodology · Statistics 2019-07-23 Yunfan Li , Jyotishka Datta , Bruce A. Craig , Anindya Bhadra

In this article we study the existence and strong consistency of GEE estimators, when the generalized estimating functions are martingales with random coefficients. Furthermore, we characterize estimating functions which are asymptotically…

Statistics Theory · Mathematics 2017-11-15 Laura Dumitrescu , Ioana Schiopu-Kratina

Causal inference methods have been applied in various fields where researchers want to estimate treatment effects. In traditional causal inference settings, one assumes that the outcome of a unit does not depend on treatments of other…

Methodology · Statistics 2022-09-05 Kelly Kung , Daniel L. Sussman

We present efficient finite difference estimators for goal-oriented sensitivity indices with applications to the generalized Langevin equation (GLE). In particular, we apply these estimators to analyze an extended variable formulation of…

Numerical Analysis · Mathematics 2018-09-18 Eric Joseph Hall , Markos A. Katsoulakis , Luc Rey-Bellet

Variational Autoencoder (VAE) is widely used as a generative model to approximate a model's posterior on latent variables by combining the amortized variational inference and deep neural networks. However, when paired with strong…

Machine Learning · Computer Science 2020-06-02 Qile Zhu , Jianlin Su , Wei Bi , Xiaojiang Liu , Xiyao Ma , Xiaolin Li , Dapeng Wu

It is known that the estimating equations for quantile regression (QR) can be solved using an EM algorithm in which the M-step is computed via weighted least squares, with weights computed at the E-step as the expectation of independent…

Methodology · Statistics 2021-08-26 Haim Bar , James Booth , Martin T. Wells

The integral-algebraic equation (IAE) is a mixed system of first-kind and second-kind Volterra integral equations (VIEs). This paper mainly focuses on the discontinuous Galerkin (DG) method to solve index-2 IAEs. First, the convergence…

Numerical Analysis · Mathematics 2024-10-10 Hecong Gao , Hui Liang

Variational autoencoder (VAE) is a very successful generative model whose key element is the so called amortized inference network, which can perform test time inference using a single feed forward pass. Unfortunately, this comes at the…

Machine Learning · Computer Science 2021-02-08 Minyoung Kim , Vladimir Pavlovic

We consider the Generalized Gibbs Ensemble (GGE) in the context of global quantum quenches in XXZ Heisenberg spin chains. Embedding the GGE into the Quantum Transfer Matrix formalism we develop an iterative procedure to fix the…

Statistical Mechanics · Physics 2015-06-15 Balázs Pozsgay

Several statistical models used in genome-wide prediction assume independence of marker allele substitution effects, but it is known that these effects might be correlated. In statistics, graphical models have been identified as a useful…

Quantitative Methods · Quantitative Biology 2017-04-13 Carlos Alberto Martínez , Kshitij Khare , Syed Rahman , Mauricio A. Elzo

Bayesian inference for survival regression modeling offers numerous advantages, especially for decision-making and external data borrowing, but demands the specification of the baseline hazard function, which may be a challenging task. We…

Nonlinear relationships between covariates and a response variable of interest are frequently encountered in animal science research. Within statistical models, these nonlinear effects have, traditionally, been handled using a range of…

Applications · Statistics 2025-10-28 Gavin L. Simpson

Important problems in causal inference, economics, and, more generally, robust machine learning can be expressed as conditional moment restrictions, but estimation becomes challenging as it requires solving a continuum of unconditional…

Machine Learning · Computer Science 2024-02-19 Heiner Kremer , Jia-Jie Zhu , Krikamol Muandet , Bernhard Schölkopf

In the low-dimensional case, the generalized additive coefficient model (GACM) proposed by Xue and Yang [Statist. Sinica 16 (2006) 1423-1446] has been demonstrated to be a powerful tool for studying nonlinear interaction effects of…

Statistics Theory · Mathematics 2015-10-15 Shujie Ma , Raymond J. Carroll , Hua Liang , Shizhong Xu

We propose generalized resubstitution error estimators for regression, a broad family of estimators, each corresponding to a choice of empirical probability measures and loss function. The usual sum of squares criterion is a special case…

Machine Learning · Computer Science 2024-10-24 Diego Marcondes , Ulisses Braga-Neto

General Effect Modelling (GEM) is an umbrella over different methods that utilise effects in the analyses of data with multiple design variables and multivariate responses. To demonstrate the methodology, we here use GEM in gene expression…

This paper introduces a novel kernel density estimator (KDE) based on the generalised exponential (GE) distribution, designed specifically for positive continuous data. The proposed GE KDE offers a mathematically tractable form that avoids…

Methodology · Statistics 2026-02-18 Laura M. Craig , Wagner Barreto-Souza