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Decentralized large language model (LLM) inference promises transparent and censorship resistant access to advanced AI, yet existing verification approaches struggle to scale to modern models. Proof of Quality (PoQ) replaces cryptographic…

Artificial Intelligence · Computer Science 2025-12-19 Arther Tian , Alex Ding , Frank Chen , Alan Wu , Aaron Chan , Bruce Zhang

The global demand for sustainable protein sources has accelerated the need for intelligent tools that can rapidly process and synthesise domain-specific scientific knowledge. In this study, we present a proof-of-concept multi-agent…

Artificial Intelligence · Computer Science 2025-06-26 Alexander D. Kalian , Jaewook Lee , Stefan P. Johannesson , Lennart Otte , Christer Hogstrand , Miao Guo

Protein tertiary structure defines its functions, classification and binding sites. Similar structural characteristics between two proteins often lead to the similar characteristics thereof. Determining structural similarity accurately in…

Computer Vision and Pattern Recognition · Computer Science 2016-10-05 Rezaul Karim , Md. Momin Al Aziz , Swakkhar Shatabda , M. Sohel Rahman

Although large multi-modality models (LMMs) have seen extensive exploration and application in various quality assessment studies, their integration into Point Cloud Quality Assessment (PCQA) remains unexplored. Given LMMs' exceptional…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Zicheng Zhang , Haoning Wu , Yingjie Zhou , Chunyi Li , Wei Sun , Chaofeng Chen , Xiongkuo Min , Xiaohong Liu , Weisi Lin , Guangtao Zhai

In recent years, work has gone into developing deep interpretable methods for image classification that clearly attributes a model's output to specific features of the data. One such of these methods is the Prototypical Part Network…

Machine Learning · Computer Science 2024-06-05 Aaron J. Li , Robin Netzorg , Zhihan Cheng , Zhuoqin Zhang , Bin Yu

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

Automated and robust portrait quality assessment (PQA) is of paramount importance in high-impact applications such as smartphone photography. This paper presents FHIQA, a learning-based approach to PQA that introduces a simple but effective…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Nicolas Chahine , Sira Ferradans , Javier Vazquez-Corral , Jean Ponce

This paper proposes a data driven model to predict the performance of a face recognition system based on image quality features. We model the relationship between image quality features (e.g. pose, illumination, etc.) and recognition…

Computer Vision and Pattern Recognition · Computer Science 2015-10-27 Abhishek Dutta , Raymond Veldhuis , Luuk Spreeuwers

Quality Estimation (QE) is estimating quality of the model output during inference when the ground truth is not available. Deriving output quality from the models' output probability is the most trivial and low-effort way. However, we show…

Computation and Language · Computer Science 2025-09-16 Tu Anh Dinh , Jan Niehues

Motivation: Proteins are of great significance in living organisms. However, understanding their functions encounters numerous challenges, such as insufficient integration of multimodal information, a large number of training parameters,…

Machine Learning · Computer Science 2025-05-23 Zhicong Wang , Zicheng Ma , Ziqiang Cao , Changlong Zhou , Jun Zhang , Yiqin Gao

Protein dynamics underlie many biological functions, yet remain difficult to characterize due to the high computational cost of molecular dynamics simulations and the scarcity of dynamic structural data. This survey reviews recent advances…

Biomolecules · Quantitative Biology 2026-04-29 Haocheng Tang , Liang Shi , Ya-Shi Zhang , Xixian Liu , Jian Tang , Jiarui Lu

We present the task of PreQuEL, Pre-(Quality-Estimation) Learning. A PreQuEL system predicts how well a given sentence will be translated, without recourse to the actual translation, thus eschewing unnecessary resource allocation when…

Computation and Language · Computer Science 2022-12-06 Shachar Don-Yehiya , Leshem Choshen , Omri Abend

Energy is now a first-class design constraint along with performance in all computing settings. Energy predictive modelling based on performance monitoring counts (PMCs) is the leading method used for prediction of energy consumption during…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-09-28 Arsalan Shahid , Muhammad Fahad , Ravi Reddy Manumachu , Alexey Lastovetsky

Drive towards improved performance of machine learning models has led to the creation of complex features representing a database of condensed matter systems. The complex features, however, do not offer an intuitive explanation on which…

Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

The goal of full-reference image quality assessment (FR-IQA) is to predict the quality of an image as perceived by human observers with using its pristine, reference counterpart. In this study, we explore a novel, combined approach which…

Computer Vision and Pattern Recognition · Computer Science 2020-12-04 Domonkos Varga

Existing power modelling research focuses on the model rather than the process for developing models. An automated power modelling process that can be deployed on different processors for developing power models with high accuracy is…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-03-19 Kai Chen , Peter Kilpatrick , Dimitrios S. Nikolopoulos , Blesson Varghese

Image quality assessment (IQA) focuses on the perceptual visual quality of images, playing a crucial role in downstream tasks such as image reconstruction, compression, and generation. The rapid advancement of multi-modal large language…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Weiqi Li , Xuanyu Zhang , Shijie Zhao , Yabin Zhang , Junlin Li , Li Zhang , Jian Zhang

The ability to precisely derive mathematical objects is a core requirement for downstream STEM applications, including mathematics, physics, and chemistry, where reasoning must culminate in formally structured expressions. Yet, current LM…

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer