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Experimental studies are prevalent in Evolutionary Computation (EC), and concerns about the reproducibility and replicability of such studies have increased in recent times, reflecting similar concerns in other scientific fields. In this…

Artificial Intelligence · Computer Science 2022-03-30 Manuel López-Ibáñez , Juergen Branke , Luís Paquete

Hand-sized Deoxyribonucleic acid (DNA) sequencing machines are of growing importance in several life sciences fields as their small footprints enable a broader range of use cases than their larger, stationary counterparts. However, as…

Hardware Architecture · Computer Science 2025-10-13 Abel Beyene , Zhongpan Wu , Yunus Dawji , Karim Hammad , Ebrahim Ghafar-Zadeh , Sebastian Magierowski

Bioinformatics encompass storing, analyzing and interpreting the biological data. Most of the challenges for Machine Learning methods like Cellular Automata is to furnish the functional information with the corresponding biological…

Computational Engineering, Finance, and Science · Computer Science 2014-04-25 Pokkuluri Kiran Sree , Inampudi Ramesh Babu , SSSN Usha Devi N

Accurate classification of blood cells plays a vital role in hematological analysis as it aids physicians in diagnosing various medical conditions. In this study, we present a novel approach for classifying blood cell images known as…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Yongcheng Li , Lingcong Cai , Ying Lu , Yupeng Zhang , Jingyan Jiang , Genan Dai , Bowen Zhang , Jingzhou Cao , Xiangzhong Zhang , Xiaomao Fan

Recently, advancements in deep learning-based superpixel segmentation methods have brought about improvements in both the efficiency and the performance of segmentation. However, a significant challenge remains in generating superpixels…

Computer Vision and Pattern Recognition · Computer Science 2023-10-12 Tingyu Zhao , Bo Peng , Yuan Sun , Daipeng Yang , Zhenguang Zhang , Xi Wu

Reversible Cellular Automata (RCA) are a particular kind of shift-invariant transformations characterized by a dynamics composed only of disjoint cycles. They have many applications in the simulation of physical systems, cryptography and…

Neural and Evolutionary Computing · Computer Science 2021-05-26 Luca Mariot , Stjepan Picek , Domagoj Jakobovic , Alberto Leporati

Cellular processes are governed by macromolecular complexes inside the cell. Study of the native structures of macromolecular complexes has been extremely difficult due to lack of data. With recent breakthroughs in Cellular electron cryo…

Quantitative Methods · Quantitative Biology 2018-06-12 Chengqian Che , Ruogu Lin , Xiangrui Zeng , Karim Elmaaroufi , John Galeotti , Min Xu

Biological systems exhibit remarkable morphogenetic plasticity, where a single genome can encode various specialized cellular structures triggered by local chemical signals. In the domain of Deep Learning, Differentiable Neural Cellular…

Neural and Evolutionary Computing · Computer Science 2025-12-10 Ali Sakour

Reliably distinguishing between cells based on minute differences in receptor density is crucial for cell-cell or virus-cell recognition, the initiation of signal transduction and selective targeting in directed drug delivery. Such sharp…

Soft Condensed Matter · Physics 2021-10-04 Christine Linne , Daniele Visco , Stefano Angioletti-Uberti , Liedewij Laan , Daniela J. Kraft

Understanding cell identity is an important task in many biomedical areas. Expression patterns of specific marker genes have been used to characterize some limited cell types, but exclusive markers are not available for many cell types. A…

Recent tumor genome sequencing confirmed that one tumor often consists of multiple cell subpopulations (clones) which bear different, but related, genetic profiles such as mutation and copy number variation profiles. Thus far, one tumor has…

Molecular Networks · Quantitative Biology 2014-09-09 Edwin Wang , Jinfeng Zou , Naif Zaman , Lenore K. Beitel , Mark Trifiro , Miltiadis Paliouras

The base station-mobile device communication traffic has dramatically increased recently due to mobile data, which in turn heavily overloaded the underlying infrastructure. To decrease Base Station (BS) interaction, intra-cell communication…

Information Theory · Computer Science 2021-10-04 Elif Haytaoglu , Erdi Kaya , Suayb S. Arslan

An adaptive Monte Carlo localization algorithm based on coevolution mechanism of ecological species is proposed. Samples are clustered into species, each of which represents a hypothesis of the robots pose. Since the coevolution between the…

Robotics · Computer Science 2007-05-23 Luo Ronghua , Hong Bingrong

In this work we propose an autoencoder based framework for simultaneous reconstruction and classification of biomedical signals. Previously these two tasks, reconstruction and classification were treated as separate problems. This is the…

Signal Processing · Electrical Eng. & Systems 2019-12-30 Anupriya Gogna , Angshul Majumdar , Rabab Ward

We propose a novel dynamic image reconstruction method from PET listmode data that could be particularly suited to tracking single or small numbers of cells. In contrast to conventional PET reconstruction our method combines the information…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Bernhard Schmitzer , Klaus P. Schäfers , Benedikt Wirth

In multicellular organisms, cells coordinate their activities through cell-cell communication (CCC), which is crucial for development, tissue homeostasis, and disease progression. Recent advances in single-cell and spatial omics…

Quantitative Methods · Quantitative Biology 2026-03-24 Xiangzheng Cheng , Haili Huang , Ye Su , Qing Nie , Xiufen Zou , Suoqin Jin

We present a new Markov chain Monte Carlo algorithm, implemented in software Arbores, for inferring the history of a sample of DNA sequences. Our principal innovation is a bridging procedure, previously applied only for simple stochastic…

Computation · Statistics 2019-03-06 Kari Heine , Alex Beskos , Ajay Jasra , David Balding , Maria De Iorio

Clustering consists of grouping together samples giving their similar properties. The problem of modeling simultaneously groups of samples and features is known as Co-Clustering. This paper introduces ROCCO - a Robust Continuous…

Machine Learning · Computer Science 2018-02-15 Xiao He , Luis Moreira-Matias

Constructing cell developmental trajectories is a critical task in single-cell RNA sequencing (scRNA-seq) analysis, enabling the inference of potential cellular progression paths. However, current automated methods are limited to…

Computational Geometry · Computer Science 2025-07-31 Qipeng Wang , Shaolun Ruan , Rui Sheng , Yong Wang , Min Zhu , Huamin Qu

This paper introduces a speciation principle for neuroevolution where evolving networks are grouped into species based on the number of hidden neurons, which is indicative of the complexity of the search space. This speciation principle is…

Neural and Evolutionary Computing · Computer Science 2020-10-13 Alexander Hadjiivanov , Alan Blair