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We introduce a non-invasive approach for optogenetic regulation in biological cells through highly scattering skull tissue using wavefront shaping. The wavefront of the incident light was systematically controlled using a spatial light…

Optical approaches for wavefront shaping traditionally rely on phase modulation through holographic techniques. Shaping the phase determines a wave's diffraction and hence its intensity distribution in space. We instead show that shaping…

We present an optical wavefront shaping approach that allows tracking and localization of signal hidden inside or behind a scattering medium. The method combines traditional feedback based wavefront shaping together with a switch function,…

Wavefront shaping is a technique for directing light through turbid media. The theoretical aspects of wavefront shaping are well understood, and under near-ideal experimental conditions, accurate predictions for the expected signal…

Optics · Physics 2024-07-01 Bahareh Mastiani , Daniël W. S. Cox , Ivo M. Vellekoop

The presence of a scattering medium in the imaging path between an object and an observer is known to severely limit the visual acuity of the imaging system. We present an approach to circumvent the deleterious effects of scattering, by…

A random medium can serve as a controllable arbitrary spectral filter with spectral resolution determined by the inverse of the interaction time of the light in the medium. We use wavefront shaping to implement an arbitrary spectral…

Optics · Physics 2015-06-05 Eran Small , Ori Katz , Yefeng Guan , Yaron Silberberg

Adaptive optics in combination with multi-photon techniques is a powerful approach to image deep into a specimen. Remarkably, virtually all adaptive optics schemes today rely on wavefront modulators which are reflective, diffractive, or…

Light with complex structures in polarization, phase and amplitude, has attracted a lot of attention in a broad range of applications and fundamental studies in classical and quantum optics. Along with the increased interest in structured…

Optics · Physics 2026-04-22 Oussama Korichi , Markus Hiekkamaki , Robert Fickler

Limited access to corrective eyewear remains a significant medical, societal, and economic challenge, even in the 21st century. More than 1 billion people suffer from uncorrected vision impairment, with the vast majority residing in…

Applied Physics · Physics 2024-06-17 Mor Elgarisi , Omer Luria , Yotam Katzman , Daniel Widerker , Valeri Frumkin , Moran Bercovici

Integrating conventional optics into compact nanostructured surfaces is the goal of flat optics. Despite the enormous progress of this technology, there are still critical challenges for real world applications due to a limited efficiency…

Wavefront shaping makes it possible to form a focus through opaque scattering materials. In some cases, this focus may be scanned over a small distance using the optical memory effect. However, in many cases of interest, the optical memory…

Optics · Physics 2020-01-08 Bahareh Mastiani , Tzu-Lun Ohn , Ivo M. Vellekoop

When light propagates through a multimode optical fibre (MMF), the spatial information it carries is scrambled. Wavefront shaping can undo this scrambling, typically one spatial mode at a time - enabling deployment of MMFs as ultra-thin…

Light scattering in inhomogeneous media induces wavefront distortions which pose an inherent limitation in many optical applications. Examples range from microscopy and nanosurgery to astronomy. In recent years, ongoing efforts have made…

Optics · Physics 2015-05-20 Ori Katz , Yaron Bromberg , Eran Small , Yaron Silberberg

Wavefront shaping is increasingly being used in modern microscopy to obtain distortion-free, high-resolution images deep inside inhomogeneous media. Wavefront shaping methods typically rely on the presence of a 'guidestar' in order to find…

Wavefront shaping enables control of classical light through scattering media. Extending these techniques to spatially entangled photons promises new quantum applications, but their fundamental limits, especially when both photons scatter,…

Quantum Physics · Physics 2025-05-06 Ronen Shekel , Sébastien M. Popoff , Yaron Bromberg

Transformation optics offers an unconventional approach to the control of electromagnetic fields. A transformation optical structure is designed by first applying a form-invariant coordinate transform to Maxwell's equations, in which part…

Wavefront shaping techniques allow waves to be focused on a diffraction-limited target deep inside disordered media. To identify the target position, a guidestar is required that typically emits a frequency-shifted signal. Here we present a…

Applied Physics · Physics 2025-05-13 Antton Goïcoechea , Jakob Hüpfl , Stefan Rotter , François Sarrazin , Matthieu Davy

Optical time-reversal techniques are being actively developed to focus light through or inside opaque scattering media. When applied to biological tissue, these techniques promise to revolutionize biophotonics by enabling deep-tissue…

Biological Physics · Physics 2016-11-07 Yuecheng Shen , Yan Liu , Cheng Ma , Lihong V. Wang

Scattering in complex media scrambles light, thus obscuring images and limiting applications from astronomy to microscopy. Existing computational and wavefront-shaping methods treat scattering as a linear optical-wave inversion problem that…

Quantum Physics · Physics 2026-03-18 Chloé Vernière , Raphaël Guitter , Baptiste Courme , Hugo Defienne

In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The…

Optics · Physics 2021-01-07 Antoine Boniface , Jonathan Dong , Sylvain Gigan