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We describe a strategy for constructing codes for DNA-based information storage by serial composition of weighted finite-state transducers. The resulting state machines can integrate correction of substitution errors; synchronization by…

Information Theory · Computer Science 2016-11-18 Ian Holmes

As a medium for cold data storage, DNA stands out as it promises significant gains in storage capacity and lifetime. However, it comes with its own data processing challenges to overcome. Constrained codes over the DNA alphabet…

Information Theory · Computer Science 2025-10-08 Canberk İrimağzı , Ahmed Hareedy

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Yonatan Yehezkeally

Composite DNA is a recent method to increase the base alphabet size in DNA-based data storage.This paper models synthesizing and sequencing of composite DNA and introduces coding techniques to correct substitutions, losses of entire…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Omer Sabary , Antonia Wachter-Zeh , Eitan Yaakobi

DNA Data storage has recently attracted much attention due to its durable preservation and extremely high information density (bits per gram) properties. In this work, we propose a hybrid coding strategy comprising of generalized…

Information Theory · Computer Science 2021-12-20 Yixin Wang , Li Deng , Md. Noor-A-Rahim , Erry Gunawan , Yong L. Guan , Zhi P. Shi , Chueh L. Poh

The problem of error control in random linear network coding is addressed from a matrix perspective that is closely related to the subspace perspective of K\"otter and Kschischang. A large class of constant-dimension subspace codes is…

Information Theory · Computer Science 2019-05-07 Danilo Silva , Frank R. Kschischang , Ralf Kötter

The construction of deletion codes for the Levenshtein metric is reduced to the construction of codes over the integers for the Manhattan metric by run length coding. The latter codes are constructed by expurgation of translates of…

Information Theory · Computer Science 2014-06-05 Lin Sok , Patrick Solé , Aslan Tchamkerten

In this paper, we study error-correcting codes for the storage of data in synthetic deoxyribonucleic acid (DNA). We investigate a storage model where data is represented by an unordered set of $M$ sequences, each of length $L$. Errors…

Information Theory · Computer Science 2018-05-10 Andreas Lenz , Paul H. Siegel , Antonia Wachter-Zeh , Eitan Yaakobi

Storing digital data in synthetic DNA faces challenges in ensuring data reliability in the presence of edit errors--deletions, insertions, and substitutions--that occur randomly during various stages of the storage process. Current…

Information Theory · Computer Science 2025-09-11 Serge Kas Hanna

Levenshtein distance is a commonly used edit distance metric, typically applied in language processing, and to a lesser extent, in molecular biology analysis. Biological nucleic acid sequences are often embedded in longer sequences and are…

Quantitative Methods · Quantitative Biology 2023-10-20 Robert Logan , Amy W. Wehe , Dori C. Woods , Jon Tilly , Konstantin Khrapko

This paper studies the cardinality of codes correcting insertions and deletions. We give improved upper and lower bounds on code size. Our upper bound is obtained by utilizing the asymmetric property of list decoding for insertions and…

Information Theory · Computer Science 2023-12-14 Kenji Yasunaga

DNA codes have many applications, such as in data storage, DNA computing, etc. Good DNA codes have large sizes and satisfy some certain constraints. In this paper, we present a new construction method for reversible DNA codes. We show that…

Information Theory · Computer Science 2024-03-19 Xueyan Chen , Whan-Hyuk Choi , Hongwei Liu

We improve Levenshtein's upper bound for the cardinality of a code of length four that is capable of correcting single deletions over an alphabet of even size. We also illustrate that the new upper bound is sharp. Furthermore we construct…

Information Theory · Computer Science 2010-03-23 Hyun Kwang Kim , Joon Yop Lee , Dong Yeol Oh

Permutation codes have recently garnered substantial research interest due to their potential in various applications including cloud storage systems, genome resequencing and flash memories. In this paper, we study the theoretical bounds…

Information Theory · Computer Science 2020-01-06 Siyi Yang , Clayton Schoeny , Lara Dolecek

DNA is a promising storage medium, but its stability and occurrence of Indel errors pose a significant challenge. The relative occurrence of Guanine(G) and Cytosine(C) in DNA is crucial for its longevity, and reverse complementary base…

Information Theory · Computer Science 2024-01-15 NallappaBhavithran G , Selvakumar R

DNA is an attractive candidate for data storage. Its millennial durability and nanometer scale offer exceptional data density and longevity. Its relevance to medical applications also drives advances in DNA-related biotechnology. To protect…

Information Theory · Computer Science 2025-11-25 Yu-Ting Lin , Hsin-Po Wang , Venkatesan Guruswami

We consider the problem of correcting insertion and deletion errors in the $d$-dimensional space. This problem is well understood for vectors (one-dimensional space) and was recently studied for arrays (two-dimensional space). For vectors…

Information Theory · Computer Science 2022-08-11 Evagoras Stylianou , Lorenz Welter , Rawad Bitar , Antonia Wachter-Zeh , Eitan Yaakobi

Due to its high data density and longevity, DNA is considered a promising medium for satisfying ever-increasing data storage needs. However, the diversity of errors that occur in DNA sequences makes efficient error-correction a challenging…

Information Theory · Computer Science 2020-11-12 Yuanyuan Tang , Farzad Farnoud

A (tandem) duplication of length $ k $ is an insertion of an exact copy of a substring of length $ k $ next to its original position. This and related types of impairments are of relevance in modeling communication in the presence of…

Information Theory · Computer Science 2020-08-13 Mladen Kovačević , Vincent Y. F. Tan

Rank modulation is a way of encoding information to correct errors in flash memory devices as well as impulse noise in transmission lines. Modeling rank modulation involves construction of packings of the space of permutations equipped with…

Information Theory · Computer Science 2011-10-13 Arya Mazumdar , Alexander Barg , Gilles Zémor