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When treatment policy estimands are of interest, clinical trials often attempt to collect patient data after intercurrent events (ICEs), although such data are often limited. Retrieved dropout imputation methods, which use pre-ICE and…

Methodology · Statistics 2026-03-31 Brendah Nansereko , Marcel Wolbers , James R. Carpenter , Jonathan W. Bartlett

Classifying incomplete multi-view data is inevitable since arbitrary view missing widely exists in real-world applications. Although great progress has been achieved, existing incomplete multi-view methods are still difficult to obtain a…

Machine Learning · Computer Science 2023-04-12 Mengyao Xie , Zongbo Han , Changqing Zhang , Yichen Bai , Qinghua Hu

Modern data acquisition based on high-throughput technology is often facing the problem of missing data. Algorithms commonly used in the analysis of such large-scale data often depend on a complete set. Missing value imputation offers a…

Applications · Statistics 2014-06-03 Daniel J. Stekhoven , Peter Bühlmann

Standard approaches for variable selection in linear models are not tailored to deal properly with high-dimensional and incomplete data. Currently, methods dedicated to high-dimensional data handle missing values by ad-hoc strategies, like…

Methodology · Statistics 2021-06-09 Avner Bar-Hen , Vincent Audigier

We consider statistical procedures for hypothesis testing of real valued functionals of matched pairs with missing values. In order to improve the accuracy of existing methods, we propose a novel multiplication combination procedure.…

Statistics Theory · Mathematics 2018-01-29 Lubna Amro , Frank Konietschke , Markus Pauly

The prevalence of missing values in data science poses a substantial risk to any further analyses. Despite a wealth of research, principled nonparametric methods to deal with general non-monotone missingness are still scarce. Instead,…

Machine Learning · Statistics 2026-05-04 Gitte Kremling , Jeffrey Näf , Johannes Lederer

Identification of charged particles in a multilayer detector by the energy loss technique may also be achieved by the use of a neural network. The performance of the network becomes worse when a large fraction of information is missing, for…

Methodology · Statistics 2020-04-14 S. Riggi , D. Riggi , F. Riggi

Missing data is common in applied data science, particularly for tabular data sets found in healthcare, social sciences, and natural sciences. Most supervised learning methods only work on complete data, thus requiring preprocessing such as…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas M. Bosschieter , Roberto Halpin-Gregorio , Madeleine Udell

The problem of missing data, usually absent incurated and competition-standard datasets, is an unfortunate reality for most machine learning models used in industry applications. Recent work has focused on understanding the nature and the…

Machine Learning · Computer Science 2022-01-25 Spyridon Mouselinos , Kyriakos Polymenakos , Antonis Nikitakis , Konstantinos Kyriakopoulos

Mixup refers to interpolation-based data augmentation, originally motivated as a way to go beyond empirical risk minimization (ERM). Its extensions mostly focus on the definition of interpolation and the space (input or feature) where it…

Machine Learning · Computer Science 2023-11-10 Shashanka Venkataramanan , Ewa Kijak , Laurent Amsaleg , Yannis Avrithis

The analysis of a protein-expression pattern from tissue microarray (TMA) data will not immediately give an answer on synergistic or antagonistic effects between the expression of the observed proteins. But contrary to apparent first…

Molecular Networks · Quantitative Biology 2018-03-07 H Buerger , F Boecker , J Packeisen , K Agelopoulos , K Poos , W Nadler , E Korsching

Next-generation RNA sequencing (RNA-seq) technology has been widely used to assess full-length RNA isoform abundance in a high-throughput manner. RNA-seq data offer insight into gene expression levels and transcriptome structures, enabling…

Applications · Statistics 2021-12-01 Wei Vivian Li , Anqi Zhao , Shihua Zhang , Jingyi Jessica Li

Coupling a multi-capillary column (MCC) with an ion mobility (IM) spectrometer (IMS) opened a multitude of new application areas for gas analysis, especially in a medical context, as volatile organic compounds (VOCs) in exhaled breath can…

Other Computer Science · Computer Science 2014-05-22 Dominik Kopczynski , Sven Rahmann

Untargeted metabolomics based on liquid chromatography-mass spectrometry technology is quickly gaining widespread application given its ability to depict the global metabolic pattern in biological samples. However, the data is noisy and…

Methodology · Statistics 2026-03-24 Guoxuan Ma , Jian Kang , Tianwei Yu

When conducting a paired $2\times2$ crossover design, each subject is paired with another subject with similar characteristics. The pair is then randomized to the same sequence of two treatments. That is, the two subjects receive the first…

Statistics Theory · Mathematics 2008-12-18 Laura J. Simon , Vernon M. Chinchilli

Mass spectrometry provides a high-throughput way to identify proteins in biological samples. In a typical experiment, proteins in a sample are first broken into their constituent peptides. The resulting mixture of peptides is then subjected…

Applications · Statistics 2010-11-10 Qunhua Li , Michael J. MacCoss , Matthew Stephens

In clinical practice, full imaging is not always feasible, often due to complex acquisition protocols, stringent privacy regulations, or specific clinical needs. However, missing MR modalities pose significant challenges for tasks like…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Tabular data are central to many applications, especially longitudinal data in healthcare, where missing values are common, undermining model fidelity and reliability. Prior imputation methods either impose restrictive assumptions or…

Machine Learning · Computer Science 2025-09-30 Dengyi Liu , Honggang Wang , Hua Fang

The missing data issue is ubiquitous in health studies. Variable selection in the presence of both missing covariates and outcomes is an important statistical research topic but has been less studied. Existing literature focuses on…

Methodology · Statistics 2021-07-09 Liangyuan Hu , Jung-Yi Joyce Lin , Jiayi Ji

Robust clustering from incomplete data is an important topic because, in many practical situations, real data sets are heavy-tailed, asymmetric, and/or have arbitrary patterns of missing observations. Flexible methods and algorithms for…

Methodology · Statistics 2018-11-13 Yuhong Wei , Yang Tang , Paul D. McNicholas