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Background: Mobile phone sensor technology has great potential in providing behavioral markers of mental health. However, this promise has not yet been brought to fruition. Objective: The objective of our study was to examine challenges…

Computers and Society · Computer Science 2018-08-01 Tjeerd W Boonstra , Jennifer Nicholas , Quincy JJ Wong , Frances Shaw , Samuel Townsend , Helen Christensen

In causal analysis, understanding the causal mechanisms through which an intervention or treatment affects an outcome is often of central interest. We propose a test to evaluate (i) whether the causal effect of a treatment that is randomly…

Econometrics · Economics 2026-03-05 Martin Huber , Kevin Kloiber , Lukáš Lafférs

Estimation of social influence in networks can be substantially biased in observational studies due to homophily and network correlation in exposure to exogenous events. Randomized experiments, in which the researcher intervenes in the…

Social and Information Networks · Computer Science 2017-09-28 Sean J. Taylor , Dean Eckles

Randomized experiments are the gold standard for estimating the causal effects of an intervention. In the simplest setting, each experimental unit is randomly assigned to receive treatment or control, and then the outcomes in each treatment…

Methodology · Statistics 2020-06-05 Guillaume Basse , Yi Ding , Panos Toulis

Mental health conditions remain underdiagnosed even in countries with common access to advanced medical care. The ability to accurately and efficiently predict mood from easily collectible data has several important implications for the…

We propose a novel approach for causal mediation analysis based on changes-in-changes assumptions restricting unobserved heterogeneity over time. This allows disentangling the causal effect of a binary treatment on a continuous outcome into…

Econometrics · Economics 2020-10-13 Martin Huber , Mark Schelker , Anthony Strittmatter

In this paper we review an approach to estimating the causal effect of a time-varying treatment on time to some event of interest. This approach is designed for the situation where the treatment may have been repeatedly adapted to patient…

Statistics Theory · Mathematics 2007-06-13 J. J. Lok , R. D. Gill , A. W. van der Vaart , J. M. Robins

Text-based conversational agents (CAs) are increasingly used in mental health, yet evaluation practices remain fragmented. We conducted a PRISMA-guided systematic review (May-June 2024) across ACM Digital Library, Scopus, and PsycINFO. From…

Human-Computer Interaction · Computer Science 2026-02-23 Jiangtao Gong , Xiao Wen , Fengyi Tao , Xinqi Wang , Xixi Yang , Yangrong Tang

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are…

Methodology · Statistics 2023-01-23 Lars Lau Raket

Data from both a randomized trial and an observational study are sometimes simultaneously available for evaluating the effect of an intervention. The randomized data typically allows for reliable estimation of average treatment effects but…

Methodology · Statistics 2021-12-01 David Cheng , Tianxi Cai

In the past decade, large scale mobile phone data have become available for the study of human movement patterns. These data hold an immense promise for understanding human behavior on a vast scale, and with a precision and accuracy never…

Physics and Society · Physics 2016-02-17 Nathalie E. Williams , Timothy A. Thomas , Matthew Dunbar , Nathan Eagle , Adrian Dobra

Effect modification means the magnitude or stability of a treatment effect varies as a function of an observed covariate. Generally, larger and more stable treatment effects are insensitive to larger biases from unmeasured covariates, so a…

Methodology · Statistics 2018-03-12 Kwonsang Lee , Dylan S. Small , Paul R. Rosenbaum

Epidemiological studies are often concerned with estimating causal effects of a sequence of treatment decisions on survival outcomes. In many settings, treatment decisions do not occur at fixed, pre-specified followup times. Rather, timing…

Methodology · Statistics 2026-01-23 Arman Oganisian

College counseling centers in various universities have been tasked with the important responsibility of attending to the mental health needs of their students. Owing to the unprecedented recent surge of demand for such services, college…

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly…

Methodology · Statistics 2024-04-23 Kjetil Røysland , Pål Ryalen , Mari Nygård , Vanessa Didelez

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time.…

Machine Learning · Statistics 2017-11-07 Hossein Soleimani , Adarsh Subbaswamy , Suchi Saria

The vision for precision medicine is to use individual patient characteristics to inform a personalized treatment plan that leads to the best healthcare possible for each patient. Mobile technologies have an important role to play in this…

Social media platforms increasingly employ proactive moderation techniques, such as detecting and curbing toxic and uncivil comments, to prevent the spread of harmful content. Despite these efforts, such approaches are often criticized for…

Human-Computer Interaction · Computer Science 2025-07-30 Xiaotian Su , Naim Zierau , Soomin Kim , April Yi Wang , Thiemo Wambsganss

Background: Mental health problems are prevalent in college students. The COVID-19 pandemic exacerbated the problems, and created a surge in the popularity of telehealth and mobile health solutions. Despite that mobile health is a promising…

Human-Computer Interaction · Computer Science 2022-06-08 Xiaomei Wang , Alec Smith , Bruce Keller , Farzan Sasangohar

The methods used so far for the analysis of time changes in population health suffer from the lack of causality in their design. This results in problems with their implementation and interpretation. Here the method is presented with…

Applications · Statistics 2016-02-19 Vladislav Moltchanov