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Tests for paired censored outcomes have been extensively studied, with some justified in the context of randomization-based inference. These tests are primarily designed to detect an overall treatment effect across the entire follow-up…
In evidence synthesis, effect modifiers are typically described as variables that induce treatment effect heterogeneity at the individual level, through treatment-covariate interactions in an outcome model parametrized at such level. As…
Testing for causation, defined as the preceding impact of the past values of one variable on the current value of another one when all other pertinent information is accounted for, is increasingly utilized in empirical research of the…
One of the most significant barriers to medication treatment is patients' non-adherence to a prescribed medication regimen. The extent of the impact of poor adherence on resulting health measures is often unknown, and typical analyses…
Using observed language to understand interpersonal interactions is important in high-stakes decision making. We propose a causal research design for observational (non-experimental) data to estimate the natural direct and indirect effects…
Micro-randomized trials (MRTs) are widely used to assess the marginal and moderated effect of mobile health (mHealth) treatments delivered via mobile devices. In many applications, the mHealth treatments are categorical with multiple levels…
Sustaining long-term user engagement with mobile health (mHealth) interventions while preserving their high efficacy remains an ongoing challenge in real-world well-being applications. To address this issue, we introduce a new algorithm,…
A treatment policy defines when and what treatments are applied to affect some outcome of interest. Data-driven decision-making requires the ability to predict what happens if a policy is changed. Existing methods that predict how the…
The health effects of environmental exposures have been studied for decades, typically using standard regression models to assess exposure-outcome associations found in observational non-experimental data. We propose and illustrate a…
This paper combines causal mediation analysis with double machine learning to control for observed confounders in a data-driven way under a selection-on-observables assumption in a high-dimensional setting. We consider the average indirect…
More than one million people commit suicide every year worldwide. The costs of daily cares, social stigma and treatment issues are still hard barriers to overcome in mental health. Most symptoms of mental disorders are related to the…
Predicting mental health from smartphone and social media data on a longitudinal basis has recently attracted great interest, with very promising results being reported across many studies. Such approaches have the potential to…
Medication adherence is a problem of widespread concern in clinical care. Poor adherence is a particular problem for patients with chronic diseases requiring long-term medication because poor adherence can result in less successful…
In many mobile health interventions, treatments should only be delivered in a particular context, for example when a user is currently stressed, walking or sedentary. Even in an optimal context, concerns about user burden can restrict which…
Mobile phone metadata is increasingly used for humanitarian purposes in developing countries as traditional data is scarce. Basic demographic information is however often absent from mobile phone datasets, limiting the operational impact of…
Causal effects are commonly defined as comparisons of the potential outcomes under treatment and control, but this definition is threatened by the possibility that the treatment or control condition is not well-defined, existing instead in…
Mobile phones can record individual's daily behavioral data as a time-series. In this paper, we present an effective time-series segmentation technique that extracts optimal time segments of individual's similar behavioral characteristics…
Promotion of healthy habits help maintain and improve people health, reduce disease risks, and manage chronic illness. Regular healthy activities like walking, exercising, healthy eating, drinking water or taking medication on time require…
The delivery and assessment of quality health care is complex with many interacting and interdependent components. In terms of research design and statistical analysis, this complexity and interdependency makes it difficult to assess the…
Understanding true influence in social media requires distinguishing correlation from causation--particularly when analyzing misinformation spread. While existing approaches focus on exposure metrics and network structures, they often fail…