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Many cytoskeletal systems are now sufficiently well known to permit their precise quantitative modelling. Microtubule and actin filaments are well characterized, and the associated proteins are often known, as well as their abundance and…

Quantitative Methods · Quantitative Biology 2022-05-30 Carlos A. Lugo , Eashan Saikia , Francois Nedelec

Plasmodium stage of Physarum polycephalum behaves as a distributed dynamical pattern formation mechanism who's foraging and migration is influenced by local stimuli from a wide range of attractants and repellents. Complex protoplasmic tube…

Biological Physics · Physics 2012-04-10 Soichiro Tsuda , Jeff Jones , Andrew Adamatzky , Jonathan Mills

Animal cells are both encapsulated and subdivided by lipid bilayer membranes. Beyond just acting as boundaries, these membranes' shapes influence the function of cells and their compartments. Physically, membranes are two-dimensional fluids…

Soft Condensed Matter · Physics 2023-03-23 George Dadunashvili , Timon Idema

Many studies have shown that Physarum polycephalum slime mold is able to find the shortest path in a maze. In this paper we study this behavior in a network, using a hyperbolic model of chemotaxis. Suitable transmission and boundary…

Numerical Analysis · Mathematics 2016-01-07 Gabriella Bretti , Roberto Natalini

Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division. These flows are driven by organized contractions of the actomyosin cortex. In order to…

Adaptation and Self-Organizing Systems · Physics 2022-07-29 Busson Valentin , Saiseau Raphaël , Durand Marc

How do non-neural organisms, such as the slime mould \textit{Physarum polycephalum}, anticipate periodic events in their environment? We present a minimal, biologically inspired reservoir model that demonstrates simple temporal anticipation…

Neurons and Cognition · Quantitative Biology 2025-05-06 Polyphony Bruna , Linnéa Gyllingberg

The plasmodium of Physarum polycephalum is renowned for spanning sources of nutrients with networks of protoplasmic tubes. The networks transport nutrients and metabolites across the plasmodium's body. To imitate a hypothetical colonisation…

Adaptation and Self-Organizing Systems · Physics 2012-09-19 Andrew Adamatzky

The exchange of large and complex slide microscopy imaging data in biomedical research and pathology practice is impeded by a lack of data standardization and interoperability, which is detrimental to the reproducibility of scientific…

The design of complex materials and the formation of specific patterns often arise from the properties of the individual building blocks. In this respect, colloidal systems offer a unique opportunity because nowadays they can be synthesized…

Soft Condensed Matter · Physics 2022-03-01 Fabrizio Camerin , Emanuela Zaccarelli

This work introduces a new software package `Sesame' for the numerical computation of classical semiconductor equations. It supports 1 and 2-dimensional systems and provides tools to easily implement extended defects such as grain…

Applied Physics · Physics 2019-05-01 Benoit Gaury , Yubo Sun , Peter Bermel , Paul M. Haney

With the approach of exascale computing era, particle-based models are becoming the focus of research due to their excellent scalability. We present a new code, Slurm, which implements the classic particle-in-cell algorithm for modeling…

Computational Physics · Physics 2018-12-05 Vyacheslav Olshevsky , Fabio Bacchini , Stefaan Poedts , Giovanni Lapenta

Soft slender structures are ubiquitous in natural and artificial systems and can be observed at scales that range from the nanometric to the kilometric, from polymers to space tethers. We present a practical numerical approach to simulate…

Fluid Dynamics · Physics 2017-08-18 Mattia Gazzola , Levi H. Dudte , Andrew G. McCormick , L. Mahadevan

pyssam is a Python library for creating statistical shape and appearance models (SSAMs) for biological (and other) shapes such as bones, lungs or other organs. A point cloud best describing the anatomical 'landmarks' of the organ are…

Quantitative Methods · Quantitative Biology 2023-01-12 Josh Williams , Ali Ozel , Uwe Wolfram

Since the experimental discovery of magnetic skyrmions achieved one decade ago, there have been significant efforts to bring the virtual particles into all-electrical fully functional devices, inspired by their fascinating physical and…

We present FabSim, a toolkit developed to simplify a range of computational tasks for researchers in diverse disciplines. FabSim is flexible, adaptable, and allows users to perform a wide range of tasks with ease. It also provides a…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-09-21 Derek Groen , Agastya Bhati , James Suter , James Hetherington , Stefan Zasada , Peter Coveney

Computational experiments using spatial stochastic simulations have led to important new biological insights, but they require specialized tools, a complex software stack, as well as large and scalable compute and data analysis resources…

Computational Engineering, Finance, and Science · Computer Science 2015-08-17 Brian Drawert , Michael Trogdon , Salman Toor , Linda Petzold , Andreas Hellander

This work introduces SwarmRL, a Python package designed to study intelligent active particles. SwarmRL provides an easy-to-use interface for developing models to control microscopic colloids using classical control and deep reinforcement…

Building mathematical models of brains is difficult because of the sheer complexity of the problem. One potential starting point is through basal cognition, which gives abstract representation of a range of organisms without central nervous…

Neurons and Cognition · Quantitative Biology 2024-11-08 Linnéa Gyllingberg , Yu Tian , David J. T. Sumpter

With their high parallelism and resource needs, many scientific applications benefit from cloud deployments. Today, scientific applications are executed on dedicated pools of VMs, resulting in resource fragmentation: users pay for…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-23 Simon Shillaker , Carlos Segarra , Eleftheria Mappoura , Mayeul Fournial , Lluis Vilanova , Peter Pietzuch

Particle-in-cell methods couple mesh-based methods for the solution of continuum mechanics problems, with the ability to advect and evolve particles. They have a long history and many applications in scientific computing. However, they have…

Numerical Analysis · Mathematics 2019-09-12 R. Gassmoeller , E. Heien , E. G. Puckett , W. Bangerth