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Related papers: Massive Multi-Omics Microbiome Database (M3DB): A …

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The explosion in known microbial diversity in the last two decades has made it abundantly clear that microbes in the environment do not exist in isolation; they are members of communities. Accordingly, omics approaches such as metagenomics…

Quantitative Methods · Quantitative Biology 2024-07-15 James C. Kosmopoulos , Karthik Anantharaman

Metabolite structure identification has become the major bottleneck of the mass spectrometry based metabolomics research. Till now, number of mass spectra databases and search algorithms have been developed to address this issue. However,…

Quantitative Methods · Quantitative Biology 2021-01-12 Hansen Zhao , Xu Zhao , Huan Yao , Jiaxin Feng , Sichun Zhang , Xinrong Zhang

Dynamo is a full-stack software solution for scientific data management. Dynamo's architecture is modular, extensible, and customizable, making the software suitable for managing data in a wide range of installation scales, from a few…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-05-18 Yutaro Iiyama , Benedikt Maier , Daniel Abercrombie , Maxim Goncharov , Christoph Paus

This paper introduces M$^{3}$-20M, a large-scale Multi-Modal Molecule dataset that contains over 20 million molecules, with the data mainly being integrated from existing databases and partially generated by large language models. Designed…

Quantitative Methods · Quantitative Biology 2025-03-18 Siyuan Guo , Lexuan Wang , Chang Jin , Jinxian Wang , Han Peng , Huayang Shi , Wengen Li , Jihong Guan , Shuigeng Zhou

Apache HBase, a mainstay of the emerging Hadoop ecosystem, is a NoSQL key-value and column family hybrid database which, unlike a traditional RDBMS, is intentionally designed to scalably host large, semistructured, and heterogeneous data.…

Databases · Computer Science 2017-02-23 Georgios Drakopoulos , Andreas Kanavos , Christos Makris , Vasileios Megalooikonomou

Microbial ecology serves as a foundation for a wide range of scientific and biomedical studies. Rapidly-evolving high-throughput sequencing technology enables the comprehensive search for microbial biomarkers using longitudinal experiments.…

Big Data today is being generated at an unprecedented rate from various sources such as sensors, applications, and devices, and it often needs to be enriched based on other reference information to support complex analytical queries.…

Databases · Computer Science 2020-08-18 Xikui Wang , Michael J. Carey

Microbiomes are a vital part of the human body, engaging in tasks like food digestion and immune defense. Their structure and function must be understood in order to promote host health and facilitate swift recovery during disease. Due to…

Human-Computer Interaction · Computer Science 2025-09-01 Simon Burbach , Maria Maleshkova , Florian Centler , Tanja Joan Schmidt

The MIT SuperCloud database management system allows for rapid creation and flexible execution of a variety of the latest scientific databases, including Apache Accumulo and SciDB. It is designed to permit these databases to run on a High…

Large organizations are seeking to create new architectures and scalable platforms to effectively handle data management challenges due to the explosive nature of data rarely seen in the past. These data management challenges are largely…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-09-29 Ruoran Liu , Haruna Isah , Farhana Zulkernine

HRDBMS is a novel distributed relational database that uses a hybrid model combining the best of traditional distributed relational databases and Big Data analytics platforms such as Hive. This allows HRDBMS to leverage years worth of…

Databases · Computer Science 2019-01-28 Jason Arnold , Boris Glavic , Ioan Raicu

Summary: Data management in clinical metabolomics studies is often inadequate. To improve this situation we created LabPipe to provide a guided, customisable approach to study-specific sample collection. It is driven through a local client…

Summary: The advent of Web-based tools that assist in the analysis and visualization of macromolecules require application programming interfaces (APIs) designed for modern web frameworks. To this end, we have developed a Node.js module…

Genomics · Quantitative Biology 2019-04-09 Newlyn N. Joseph , Raktim N. Roy , Thomas A. Steitz

Distributed systems can be very large and complex. The various considerations that influence their design can result in a substantial specification, which requires a structured framework that has to be managed successfully. The purpose of…

Databases · Computer Science 2011-02-28 Jalal Laassiri , Said Elhajji , Mohamed Bouhdadi , Ghizlane Orhanou , Youssef Balouki

Distributed databases, as the core infrastructure software for internet applications, play a critical role in modern cloud services. However, existing distributed databases frequently experience system failures and performance degradation,…

Databases · Computer Science 2025-05-06 Lingzhe Zhang , Tong Jia , Mengxi Jia , Ying Li

Summary: Microbiome HiFi Amplicon Sequence Simulator (MHASS) creates realistic synthetic PacBio HiFi amplicon sequencing datasets for microbiome studies, by integrating genome-aware abundance modeling, realistic dual-barcoding strategies,…

Genomics · Quantitative Biology 2025-09-17 Rye Howard-Stone , Ion Mandoiu

Understanding the kinetics of drug-protein interactions is paramount for drug design, yet the field lacks large-scale, dynamic data to move beyond static structural analysis. Here, we present DD-03B, a massively scalable database providing…

Computational Physics · Physics 2026-04-09 Maodong Li , Dechin Chen , Zhijun Pan , Zhe Wang , Yi Isaac Yang

Biodiversity research requires complete and detailed information to study ecosystem dynamics at different scales. Employing data-driven methods like Machine Learning is getting traction in ecology and more specific biodiversity, offering…

Quantitative Methods · Quantitative Biology 2025-10-27 Stylianos Stasinos , Martino Mensio , Elena Lazovik , Athanasios Trantas

In today's world data is being generated at a high rate due to which it has become inevitable to analyze and quickly get results from this data. Most of the relational databases primarily support SQL querying with a limited support for…

Databases · Computer Science 2021-04-08 Alex Watson , Suvam Kumar Das , Suprio Ray

We present fVDB, a novel GPU-optimized framework for deep learning on large-scale 3D data. fVDB provides a complete set of differentiable primitives to build deep learning architectures for common tasks in 3D learning such as convolution,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Francis Williams , Jiahui Huang , Jonathan Swartz , Gergely Klár , Vijay Thakkar , Matthew Cong , Xuanchi Ren , Ruilong Li , Clement Fuji-Tsang , Sanja Fidler , Eftychios Sifakis , Ken Museth