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We propose a model describing the phase behavior of two-component membranes consisting of binary mixtures of electrically charged and neutral lipids. We take into account the structural phase transition (main-transition) of the hydrocarbon…

Soft Condensed Matter · Physics 2016-07-11 Naofumi Shimokawa , Hiroki Himeno , Tsutomu Hamada , Masahiro Takagi , Shigeyuki Komura , David Andelman

We propose a model for membrane-cortex adhesion which couples membrane deformations, hydrodynamics and kinetics of membrane-cortex ligands. In its simplest form, the model gives explicit predictions for the critical pressure for membrane…

Biological Physics · Physics 2016-02-10 Ricard Alert , Jaume Casademunt , Jan Brugués , Pierre Sens

Recent experimental realizations of liquid-liquid phase separation of active liquid crystals have offered an insight into the interaction between phase separation, ubiquitous in soft matter and biology, and chaotic active flows. In this…

Soft Condensed Matter · Physics 2025-04-23 Paarth Gulati , Fernando Caballero , M. Cristina Marchetti

We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

Soft Condensed Matter · Physics 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

The membrane curvature of cells and intracellular compartments continuously adapts to enable cells to perform vital functions, from cell division to signal trafficking. Understanding how membrane geometry affects these processes in vivo is…

Biological membranes are self-assembled complex fluid interfaces that host proteins, molecular motors and other macromolecules essential for cellular function. These membranes have a distinct in-plane fluid response with a surface viscosity…

Fluid Dynamics · Physics 2023-06-21 Vishnu Vig , Harishankar Manikantan

Mechanical characteristics of single biological cells are used to identify and possibly leverage interesting differences among cells or cell populations. Fluidity---hysteresivity normalized to the extremes of an elastic solid or a viscous…

Cell Behavior · Quantitative Biology 2013-10-22 John M. Maloney , Eric Lehnhardt , Alexandra F. Long , Krystyn J. Van Vliet

The statistical physics and dynamics of double supported bilayers are studied theoretically. The main goal in designing double supported lipid bilayers is to obtain model systems of biomembranes: the upper bilayer is meant to be almost…

Soft Condensed Matter · Physics 2015-03-13 Manoel Manghi , Nicolas Destainville

A cell membrane can be simply regarded as composite material consisting of lipid bilayer, membrane cytoskeleton beneath lipid bilayer, and proteins embedded in lipid bilayer and linked with membrane cytoskeleton if one only concerns its…

Other Quantitative Biology · Quantitative Biology 2007-06-26 Z. C. Tu , R. An , Z. C. Ou-Yang

The interaction of fluid membranes with a scaffold, which can be a planar surface or a more complex structure, is intrinsic to a number of systems - from artificial supported bilayers and vesicles to cellular membranes. In principle, these…

Soft Condensed Matter · Physics 2014-05-07 Daniel Schmidt , Cornelia Monzel , Timo Bihr , Rudolf Merkel , Udo Seifert , Kheya Sengupta , Ana-Sunčana Smith

Particles diffusing near interfaces face anisotropic resistance to motion due to hydrodynamic interactions. While this has been extensively studied near \textit{hard} interfaces since the works of Lorentz and Brenner, our understanding of…

Soft Condensed Matter · Physics 2026-03-03 Ali Mohammadi , Zhen Li , Sophie Marbach , Micheline Abbas

Understanding active matter has led to new perspectives on biophysics and non-equilibrium dynamics. However, the development of numerical tools for simulating active fluids capable of incorporating non-trivial boundaries or inclusions has…

Soft Condensed Matter · Physics 2024-02-01 Timofey Kozhukhov , Benjamin Loewe , Tyler N. Shendruk

Membrane shape fluctuations induce attractive interactions between rigid inclusions. Previous analytical studies showed that the fluctuation-induced pair interactions are rather small compared to thermal energies, but also that multi-body…

Soft Condensed Matter · Physics 2009-11-07 Thomas R Weikl

We investigated melting transitions in biological membranes in their native state that include their membrane proteins. These membranes originated from \textit{E. coli}, \textit{B. subtilis}, lung surfactant and nerve tissue from the spinal…

Biological Physics · Physics 2020-08-10 Tea Music , Fatma Tounsi , Soren B. Madsen , Denis Pollakowski , Manfred Konrad , Thomas Heimburg

We present a theory for the interaction between active particles and a passive flexible membrane. By explicitly solving for the pressure exerted by the active particles, we show that they reduce the membrane tension and bending modulus and…

Soft Condensed Matter · Physics 2026-05-22 David A. King , Thomas P. Russell , Ahmad K. Omar

Liposomes that achieve a heterogeneous and spatially organized surface through phase separation have been recognized to be a promising platform for delivery purposes. However, their design and optimization through experimentation can be…

Soft Condensed Matter · Physics 2021-11-05 Y. Wang , Y. Palzhanov , A. Quaini , M. Olshanskii , S. Majd

A motile cell, when stimulated, shows a dramatic increase in the activity of its membrane, manifested by the appearance of dynamic membrane structures such as lamellipodia, filopodia and membrane ruffles. The external stimulus turns on…

Soft Condensed Matter · Physics 2009-11-11 Nir Gov , Ajay Gopinathan

Relatively short peptides, such as toxins and antimicrobial-peptides, are known to insert themselves into cell membranes. On the basis of simple bead-spring models for the membrane lipids, the peptide, and water, detailed processes of the…

Soft Condensed Matter · Physics 2007-05-23 Mitsuharu Okazaki , Tomoki Watanabe , Naohito Urakami , Takashi Yamamoto

Actin flow in the cortical cytoskeleton underneath the cell membrane generates mechanical stresses that shape the cell surface. We study this mechanism using a hydrodynamic model of a compressible active gel polymerizing at the membrane and…

Soft Condensed Matter · Physics 2026-05-13 Kristiana Mihali , Dennis Wörthmüller , Pierre Sens
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