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The behavior of lipid bilayer is important to understand the functionality of cells like the trafficking of ions between cells. Standard procedures to explore the properties of lipid bilayer and hemifused states typically use either…

Soft Condensed Matter · Physics 2014-10-14 Jose Nabor Vargas , Ralf Seemann , Jean-Baptiste Fleury

The development of substrates with a switchable wettability is on a fast pace. The limit of switching frequencies and contact angle differences between substrate states are steadily pushed further. We investigate the behavior of a droplet…

Fluid Dynamics · Physics 2022-04-01 Leon Topp , Moritz Stieneker , Svetlana Gurevich , Andreas Heuer

The transport of individual entities through interconnected structures is a process of practical relevance both in biology and technology. Examples are given by diffusive dynamics of molecules in porous structures. In soft environments,…

Soft Condensed Matter · Physics 2026-02-09 Jakob Mihatsch , Andreas M. Menzel

Molecular rotors form twisted conformations upon photoexcitation, with their fluorescent relaxation time serving as a measure of viscosity. They have been used to assess membrane viscosities but yield higher values compared to other…

Soft Condensed Matter · Physics 2024-12-13 Vinny C. Suja , Naomi Oppenheimer , Howard A. Stone

Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that cannot be explained on the single molecule level. For example,…

Biological Physics · Physics 2009-06-09 Thomas Heimburg

Changes of external parameters in proximity of critical point can increase thermal fluctuations of tubular lipid membrane (TLM) and result in variation of the membrane shape. The phase transitions in the system are shown to be controlled by…

Soft Condensed Matter · Physics 2015-01-05 I. Yu. Golushko , S. B. Rochal , A. Parmeggiani , V. L. Lorman

We analyze the non-equilibrium shape fluctuations of giant unilamellar vesicles encapsulating motile bacteria. Owing to bacteria--membrane collisions, we experimentally observe a significant increase in the magnitude of membrane…

Soft Condensed Matter · Physics 2020-04-22 Sho C. Takatori , Amaresh Sahu

This study aims at finding a method for constructing molecular dynamics like models using the formalism of cellular automata for fast simulation of fluid dynamic systems (including compressible phenomena). In as much as the results…

comp-gas · Physics 2009-09-25 Himanshu Agrawal

Fluid membranes made out of lipid bilayers are the fundamental separation structure in eukaryotic cells. Many physiological processes rely on dramatic shape and topological changes (e.g. fusion, fission) of fluid membrane systems. Fluidity…

Numerical Analysis · Mathematics 2010-07-29 Marino Arroyo , Antonio DeSimone , Luca Heltai

Recent computational studies have reported evidence of a metastable liquid-liquid phase transition (LLPT) in molecular models of water under deeply supercooled conditions. A competing hypothesis suggests, however, that non-equilibrium…

Statistical Mechanics · Physics 2016-12-21 Jeremy C. Palmer , Rakesh S. Singh , Renjie Chen , Fausto Martelli , Pablo G. Debenedetti

Active particles under soft confinement such as droplets or vesicles present intriguing phenomena, as collective motion emerges alongside the deformation of the environment. A model is employed to systematically investigate droplet…

Soft Condensed Matter · Physics 2024-07-25 Javier Diaz , Ignacio Pagonabarraga

This article is the second of a three-part series that derives a self-consistent theoretical framework of the electromechanics of arbitrarily curved lipid membranes. Existing continuum theories commonly treat lipid membranes as strictly…

Soft Condensed Matter · Physics 2025-02-26 Yannick A. D. Omar , Zachary G. Lipel , Kranthi K. Mandadapu

It has been considered that the effective bending rigidity of fluid membranes should be reduced by thermal undulations. However, recent thorough investigation by Pinnow and Helfrich revealed significance of measure factors for the partition…

Condensed Matter · Physics 2009-11-07 Yoshihiro Nishiyama

Demixing of binary liquids is a ubiquitous transition, which is explained using a well-established thermodynamic formalism that requires equality of intensive thermodynamics parameters across the phase boundaries. Demixing transitions also…

Active matter consumes energy from the environment and transforms it into mechanical work. Notable examples from biology include cell division, bacterial swarms, and muscle contraction. In this work, we investigate the nature of active…

Soft Condensed Matter · Physics 2023-09-28 Michael J. Landry

Dynamin is a ubiquitous GTPase that tubulates lipid bilayers and is implicated in many membrane severing processes in eukaryotic cells. Setting the grounds for a better understanding of this biological function, we develop a generalized…

Soft Condensed Matter · Physics 2008-08-19 Martin Lenz , Jacques Prost , Jean-François Joanny

The phase diagram of an incompressible fluid membrane subject to quantum and thermal fluctuations is calculated exactly in a large number of dimensions of configuration space. At zero temperature, a crumpling transition is found at a…

Condensed Matter · Physics 2009-10-31 M. E. S. Borelli , H. Kleinert

Most biological molecules contain acido-basic groups that modulate their structure and interactions. A consequence is that pH gradients, local heterogeneities and dynamic variations are used by cells and organisms to drive or regulate…

In this paper, phase field models are developed for multi-component vesicle membranes with different lipid compositions and membranes with free boundary. These models are used to simulate the deformation of membranes under the elastic…

Biological Physics · Physics 2007-05-23 Xiaoqiang Wang , Qiang Du

How thousands of microtubules and molecular motors self-organize into spindles remains poorly understood. By combining static, nanometer-resolution, large-scale electron tomography reconstructions and dynamic, optical-resolution, polarized…

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