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As nuclear power expands, technical, economic, political, and environmental analyses of nuclear fuel cycles by simulators increase in importance. To date, however, current tools are often fleet-based rather than discrete and restrictively…

Development of Cyber Physical Systems (CPSs) requires close interaction between developers with expertise in many domains to achieve ever-increasing demands for improved performance, reduced cost, and more system autonomy. Each engineering…

Software Engineering · Computer Science 2020-04-14 Charles Hartsell , Nagabhushan Mahadevan , Harmon Nine , Ted Bapty , Abhishek Dubey , Gabor Karsai

Pre-trained code language models have achieved promising performance in code generation and improved the programming efficiency of human developers. However, their self-refinement capability is typically overlooked by the existing…

Software Engineering · Computer Science 2024-03-28 Yangruibo Ding , Marcus J. Min , Gail Kaiser , Baishakhi Ray

Design of next generation computer systems should be supported by simulation infrastructure that must achieve a few contradictory goals such as fast execution time, high accuracy, and enough flexibility to allow comparison between large…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-04-02 Ori Chalak , Cai Weiguang , Li Wei , Fang Lei , Zheng Libing , Wang Jintang , Wu Zuguang , Gu Xiongli , Wang Haibin , Avi Mendelson

Simulation has become an essential component of designing and developing scientific experiments. The conventional procedural approach to coding simulations of complex experiments is often error-prone, hard to interpret, and inflexible,…

Computational Physics · Physics 2023-08-09 Peter Sun , John A. Marohn

Object-oriented programming languages such as Java and Objective C have become popular for implementing agent-based and other object-based simulations since objects in those languages can {\em reflect} (i.e. make runtime queries of an…

Mathematical Software · Computer Science 2008-10-22 Russell K. Standish , Duraid Madina

Flow-sensitive type systems offer an elegant way to ensure memory-safety in programming languages. Unfortunately, their adoption in new or existing languages is often hindered by a painful effort to implement or integrate them into…

Programming Languages · Computer Science 2021-06-24 Dimitri Racordon , Aurélien Coet , Didier Buchs

Cyclic peptides offer inherent advantages in pharmaceuticals. For example, cyclic peptides are more resistant to enzymatic hydrolysis compared to linear peptides and usually exhibit excellent stability and affinity. Although deep generative…

Machine Learning · Computer Science 2025-05-28 Xiangxin Zhou , Mingyu Li , Yi Xiao , Jiahan Li , Dongyu Xue , Zaixiang Zheng , Jianzhu Ma , Quanquan Gu

This paper presents an open-source, lightweight, yet comprehensive software framework, named RPC, which integrates physics-based simulators, planning and control libraries, debugging tools, and a user-friendly operator interface. RPC…

Robotics · Computer Science 2024-09-17 Seung Hyeon Bang , Carlos Gonzalez , Gabriel Moore , Dong Ho Kang , Mingyo Seo , Luis Sentis

Model Predictive Control (MPC) is a powerful technique to control nonlinear, multi-input multi-output systems subject to input and state constraints. It is now a standard tool for trajectory tracking control of automated vehicles. As such…

Systems and Control · Electrical Eng. & Systems 2025-08-20 Georg Schildbach , Jasper Pflughaupt

In this paper, we introduce a new quantum circuit synthesis (QCS) framework, Qsyn, for developers to research, develop, test, experiment, and then contribute their QCS algorithms and tools to the framework. Our framework is more…

CPU-FPGA heterogeneous architectures are attracting ever-increasing attention in an attempt to advance computational capabilities and energy efficiency in today's datacenters. These architectures provide programmers with the ability to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-09-24 Jason Cong , Peng Wei , Cody Hao Yu , Peng Zhang

Nowadays there is a large availability of discrete event simulation software that can be easily used in different domains: from industry to supply chain, from healthcare to business management, from training to complex systems design.…

Other Computer Science · Computer Science 2010-04-20 Antonio Cimino , Francesco Longo , Giovanni Mirabelli

The availability of open-source molecular simulation software packages allows scientists and engineers to focus on running and analyzing simulations without having to write, parallelize, and validate their own simulation software. While…

Computational Physics · Physics 2025-10-03 Simon Gravelle , Cecilia M. S. Alvares , Jacob R. Gissinger , Axel Kohlmeyer

Detailed modeling of processors and high performance cycle-accurate simulators are essential for today's hardware and software design. These problems are challenging enough by themselves and have seen many previous research efforts.…

Hardware Architecture · Computer Science 2011-11-09 Mehrdad Reshadi , Nikil Dutt

We introduce Synapse motivated by the needs to estimate and emulate workload execution characteristics on high-performance and distributed heterogeneous resources. Synapse has a platform independent application profiler, and the ability to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-03 Andre Merzky , Shantenu Jha

Computer architecture simulation is essential for evaluating new designs without the need for costly tapeout. The community has developed dozens of valuable simulators that have enabled significant architectural advances. However, using and…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-01 Sabila Al Jannat , Ying Li , Mengyang He , Xuzhong Wang , Huizhi Zhao , Jingxiang Sun , Daoxuan Xu , Enze Xu , Yifan Sun

Building applications that perceive the world around them is challenging. A developer needs to (a) select and develop corresponding machine learning algorithms and models, (b) build a series of prototypes and demos, (c) balance resource…

Motivated by the need to emulate workload execution characteristics on high-performance and distributed heterogeneous resources, we introduce Synapse. Synapse is used as a proxy application (or "representative application") for real…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-03 Andre Merzky , Ming Tai Ha , Matteo Turilli , Shantenu Jha

The simulator is an R package that streamlines the process of performing simulations by creating a common infrastructure that can be easily used and reused across projects. Methodological statisticians routinely write simulations to compare…

Computation · Statistics 2016-07-04 Jacob Bien
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