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The development of new treatments often requires clinical trials with translational animal models using (pre)-clinical imaging to characterize inter-species pathological processes. Deep Learning (DL) models are commonly used to automate…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Pedro M. Gordaliza , Juan José Vaquero , Arrate Muñoz-Barrutia

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

In recent years, deep convolutional neural network-based segmentation methods have achieved state-of-the-art performance for many medical analysis tasks. However, most of these approaches rely on optimizing the U-Net structure or adding new…

Image and Video Processing · Electrical Eng. & Systems 2025-09-15 Kunpeng Mao , Ruoyu Li , Junlong Cheng , Danmei Huang , Zhiping Song , ZeKui Liu

This paper presents the first study of the complexity of the optimization problem for integer linear-exponential programs which extend classical integer linear programs with the exponential function $x \mapsto 2^x$ and the remainder…

Logic in Computer Science · Computer Science 2025-10-17 S Hitarth , Alessio Mansutti , Guruprerana Shabadi

Energy minimization algorithms, such as graph cuts, enable the computation of the MAP solution under certain probabilistic models such as Markov random fields. However, for many computer vision problems, the MAP solution under the model is…

Computer Vision and Pattern Recognition · Computer Science 2013-07-31 Yongsub Lim , Kyomin Jung , Pushmeet Kohli

Machine Learning models are increasingly used for decision making, in particular in high-stakes applications such as credit scoring, medicine or recidivism prediction. However, there are growing concerns about these models with respect to…

Machine Learning · Computer Science 2023-04-12 Julien Rouzot , Julien Ferry , Marie-José Huguet

Cell counting is a ubiquitous, yet tedious task that would greatly benefit from automation. From basic biological questions to clinical trials, cell counts provide key quantitative feedback that drive research. Unfortunately, cell counting…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Carlos X. Hernández , Mohammad M. Sultan , Vijay S. Pande

Computing high-quality graph partitions is a challenging problem with numerous applications. In this paper, we present a novel meta-heuristic for the balanced graph partitioning problem. Our approach is based on integer linear programs that…

Data Structures and Algorithms · Computer Science 2018-02-21 Alexandra Henzinger , Alexander Noe , Christian Schulz

Bacterial biofilm segmentation poses significant challenges due to lack of apparent structure, poor imaging resolution, limited contrast between conterminous cells and high density of cells that overlap. Although there exist bacterial…

Image and Video Processing · Electrical Eng. & Systems 2019-05-08 Jie Wang , Tamal Batabyal , Mingxing Zhang , Ji Zhang , Arslan Aziz , Andreas Gahlmann , Scott T. Acton

Previous work in the area of tracing CLP(FD) programs mainly focuses on providing information about control of execution and domain modification. In this paper, we present a trace structure that provides information about additional…

Software Engineering · Computer Science 2007-05-23 Magnus Agren , Tamas Szeredi , Nicolas Beldiceanu , Mats Carlsson

In this paper, we investigate the constraint typology of mixed-integer linear programming MILP formulations. MILP is a commonly used mathematical programming technique for modelling and solving real-life scheduling, routing, planning,…

Artificial Intelligence · Computer Science 2021-03-02 Vicky Mak-Hau , John Yearwood , William Moran

We propose a novel combination of methods that (i) portrays quantitative characteristics of a DNA sequence as an image, (ii) computes distances between these images, and (iii) uses these distances to output a map wherein each sequence is a…

Genomics · Quantitative Biology 2013-07-16 Lila Kari , Kathleen A. Hill , Abu Sadat Sayem , Nathaniel Bryans , Katelyn Davis , Nikesh S. Dattani

Moral reasoning is a complex cognitive process shaped by individual experiences and cultural contexts and presents unique challenges for computational analysis. While natural language processing (NLP) offers promising tools for studying…

Computation and Language · Computer Science 2025-02-21 Shivani Kumar , David Jurgens

We present a technique for neural network verification using mixed-integer programming (MIP) formulations. We derive a \emph{strong formulation} for each neuron in a network using piecewise linear activation functions. Additionally, as in…

Machine Learning · Computer Science 2022-11-29 Tu Anh-Nguyen , Joey Huchette

Detectability of failures of linear programming (LP) decoding and its potential for improvement by adding new constraints motivate the use of an adaptive approach in selecting the constraints for the LP problem. In this paper, we make a…

Information Theory · Computer Science 2007-07-13 Mohammad H. Taghavi N. , Paul H. Siegel

With the continuous trend of data explosion, delivering packets from data servers to end users causes increased stress on both the fronthaul and backhaul traffic of mobile networks. To mitigate this problem, caching popular content closer…

Networking and Internet Architecture · Computer Science 2023-11-15 Yantong Wang , Ye Hu , Zhaohui Yang , Walid Saad , Kai-Kit Wong , Vasilis Friderikos

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Avelino Javer , Jens Rittscher

We give the first data structure for the problem of maintaining a dynamic set of n elements drawn from a partially ordered universe described by a tree. We define the Line-Leaf Tree, a linear-sized data structure that supports the…

Data Structures and Algorithms · Computer Science 2011-05-03 Brent Heeringa , Marius Catalin Iordan , Louis Theran

Model reduction, which aims to learn a simpler model of the original mixed integer linear programming (MILP), can solve large-scale MILP problems much faster. Most existing model reduction methods are based on variable reduction, which…

Machine Learning · Computer Science 2026-02-04 Jiajun Li , Yixuan Li , Ran Hou , Yu Ding , Shisi Guan , Jiahui Duan , Xiongwei Han , Tao Zhong , Vincent Chau , Weiwei Wu , Wanyuan Wang

Consider a binary classification problem solved using a feed-forward artificial neural network (ANN). Let the ANN be composed of a ReLU layer and several linear layers (convolution, sum-pooling, or fully connected). We assume the network…

Logic in Computer Science · Computer Science 2024-08-27 Ingo Schmitt