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Unsupervised image segmentation and denoising are two fundamental tasks in image processing. Usually, graph based models such as multicut are used for segmentation and variational models are employed for denoising. Our approach addresses…

Computer Vision and Pattern Recognition · Computer Science 2018-01-11 Ruobing Shen , Gerhard Reinelt , Stéphane Canu

Positive linear programs (LP), also known as packing and covering linear programs, are an important class of problems that bridges computer science, operations research, and optimization. Despite the consistent efforts on this problem, all…

Data Structures and Algorithms · Computer Science 2016-11-15 Zeyuan Allen-Zhu , Lorenzo Orecchia

We study the problem of instance segmentation in biological images with crowded and compact cells. We formulate this task as an integer program where variables correspond to cells and constraints enforce that cells do not overlap. To solve…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Chong Zhang , Shaofei Wang , Miguel A. Gonzalez-Ballester , Julian Yarkony

This paper proposes a novel framework for fluorescence plant video processing. The plant research community is interested in the leaf-level photosynthetic analysis within a plant. A prerequisite for such analysis is to segment all leaves,…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Xi Yin , Xiaoming Liu , Jin Chen , David M. Kramer

Many annotation problems in computer vision can be phrased as integer linear programs (ILPs). The use of standard industrial solvers does not to exploit the underlying structure of such problems eg, the skeleton in pose estimation. The…

Computer Vision and Pattern Recognition · Computer Science 2017-09-14 Shaofei Wang , Konrad Kording , Julian Yarkony

We track the lineage of tuples throughout their database lifetime. That is, we consider a scenario in which tuples (records) that are produced by a query may affect other tuple insertions into the DB, as part of a normal workflow. As time…

Databases · Computer Science 2021-10-05 Michael Leybovich , Oded Shmueli

An important problem in biological modeling is choosing the right model. Given experimental data, one is supposed to find the best mathematical representation to describe the real-world phenomena. However, there may not be a unique model…

Dynamical Systems · Mathematics 2024-07-03 Cashous Bortner , Nicolette Meshkat

Linear programming describes the problem of optimising a linear objective function over a set of constraints on its variables. In this paper we present a solver for linear programs implemented in the proof assistant Isabelle/HOL. This…

Logic in Computer Science · Computer Science 2024-03-29 Julian Parsert

Combinatorial optimisation problems framed as mixed integer linear programmes (MILPs) are ubiquitous across a range of real-world applications. The canonical branch-and-bound algorithm seeks to exactly solve MILPs by constructing a search…

Machine Learning · Computer Science 2023-03-16 Christopher W. F. Parsonson , Alexandre Laterre , Thomas D. Barrett

Trees have long been used as a graphical representation of species relationships. However complex evolutionary events, such as genetic reassortments or hybrid speciations which occur commonly in viruses, bacteria and plants, do not fit into…

Populations and Evolution · Quantitative Biology 2017-07-24 Sebastien Roch , Kun-Chieh Wang

Mixed Integer Linear Programming (MILP) is a fundamental class of NP-hard problems that has garnered significant attention from both academia and industry. The Branch-and-Bound (B\&B) method is the dominant approach for solving MILPs and…

Machine Learning · Computer Science 2025-11-27 Tongkai Lu , Shuai Ma , Chongyang Tao

CRISPR technology has enabled large-scale cell lineage tracing for complex multicellular organisms by mutating synthetic genomic barcodes during organismal development. However, these sophisticated biological tools currently use ad-hoc and…

Quantitative Methods · Quantitative Biology 2019-04-02 Jean Feng , William S DeWitt , Aaron McKenna , Noah Simon , Amy Willis , Frederick A Matsen

There has been growing interest in implementing massive MIMO systems by one-bit analog-to-digital converters (ADCs), which have the benefit of reducing the power consumption and hardware complexity. One-bit MIMO detection arises in such a…

Information Theory · Computer Science 2023-07-04 Cheng-Yang Yu , Mingjie Shao , Wei-Kun Chen , Ya-Feng Liu , Wing-Kin Ma

Cell tracking is an essential tool in live-cell imaging to determine single-cell features, such as division patterns or elongation rates. Unlike in common multiple object tracking, in microbial live-cell experiments cells are growing,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Karina Ruzaeva , Jan-Christopher Cohrs , Keitaro Kasahara , Dietrich Kohlheyer , Katharina Nöh , Benjamin Berkels

A linear graph is a graph whose vertices are totally ordered. Biological and linguistic sequences with interactions among symbols are naturally represented as linear graphs. Examples include protein contact maps, RNA secondary structures…

Data Structures and Algorithms · Computer Science 2011-03-08 Yasuo Tabei , Daisuke Okanohara , Shuichi Hirose , Koji Tsuda

We solve large-scale mixed-integer linear programs (MILPs) via distributed asynchronous saddle point computation. This is motivated by the MILPs being able to model problems in multi-agent autonomy, e.g., task assignment problems and…

Optimization and Control · Mathematics 2022-11-23 Luke Fina , Matthew Hale

Object parsing -- the task of decomposing an object into its semantic parts -- has traditionally been formulated as a category-level segmentation problem. Consequently, when there are multiple objects in an image, current methods cannot…

Computer Vision and Pattern Recognition · Computer Science 2017-09-13 Qizhu Li , Anurag Arnab , Philip H. S. Torr

Developing and maintaining CLP programs requires visualization and explanation tools. However, existing tools are built in an ad hoc way. Therefore porting tools from one platform to another is very difficult. We have shown in previous work…

Programming Languages · Computer Science 2007-05-23 Ludovic Langevine , Pierre Deransart , Mireille Ducasse , Erwan Jahier

Cell segmentation and tracking in microscopy images are of great significance to new discoveries in biology and medicine. In this study, we propose a novel approach to combine cell segmentation and cell tracking into a unified end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Yuqian Chen , Yang Song , Chaoyi Zhang , Fan Zhang , Lauren O'Donnell , Wojciech Chrzanowski , Weidong Cai

Multiple sequence alignment is a basic procedure in molecular biology, and it is often treated as being essentially a solved computational problem. However, this is not so, and here I review the evidence for this claim, and outline the…

Populations and Evolution · Quantitative Biology 2018-08-24 David A. Morrison