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The lack of specificity in microarray experiments due to non-specific hybridization raises a serious problem for the analysis of microarray data because the residual chemical background intensity is not related to the expression degree of…

Biomolecules · Quantitative Biology 2007-05-23 Hans Binder , Stephan Preibisch , Toralf Kirsten

Precision metrology and quantum measurement often demand matter be prepared in well defined quantum states for both internal and external degrees of freedom. Laser-cooled neutral atoms localized in a deeply confining optical potential…

Quantum Physics · Physics 2009-11-13 Jun Ye , H. J. Kimble , Hidetoshi Katori

IceCube is a cubic-kilometer scale neutrino telescope located at the geographic South Pole. The detector utilizes the extremely transparent Antarctic ice as a medium for detecting Cherenkov radiation from neutrino interactions. As a result…

Instrumentation and Methods for Astrophysics · Physics 2019-08-22 Hrvoje Dujmović , Minjin Jeong , Christoph Tönnis

Quantum fluctuations in the intensity of an optical probe is noise which limits measurement precision in absorption spectroscopy. Increased probe power can offer greater precision, however, this strategy is often constrained by sample…

Quantum Physics · Physics 2021-11-29 J. Biele , S. Wollmann , J. W. Silverstone , J. C. F. Matthews , E. J. Allen

Liquid scintillator detectors are widely used in modern neutrino studies. The unique optical properties of semiconducting nanocrystals, known as quantum dots, offer intriguing possibilities for improving standard liquid scintillator,…

Instrumentation and Detectors · Physics 2012-10-16 Lindley Winslow , Raspberry Simpson

Quantifying the temperature of microdevices is critical for probing nanoscale energy transport.Such quantification is often accomplished by integrating resistance thermometers into microdevices. However, such thermometers frequently become…

Mesoscale and Nanoscale Physics · Physics 2021-05-05 Amin Reihani , Shen Yan , Yuxuan Luan , Rohith Mittapally , Edgar Meyhofer , Pramod Reddy

Nanophotonic light-matter interfaces hold great promise for quantum technologies. Enhancing local electromagnetic fields, they enable highly efficient detectors, can help realize optically connected processors, or serve as quantum…

Micro- and nanothermometry enable precise temperature monitoring and control at the micro- and nanoscale, and have become essential diagnostic tools in applications ranging from high-power microelectronics to biosensing and nanomedicine.…

Materials Science · Physics 2025-10-28 Md Shakhawath Hossain , Dylan G. Stone , G. Landry , Xiaoxue Xu , Carlo Bradac , Toan Trong Tran

Controllable atomic-scale quantum systems hold great potential as sensitive tools for nanoscale imaging and metrology. Possible applications range from nanoscale electric and magnetic field sensing to single photon microscopy, quantum…

Mesoscale and Nanoscale Physics · Physics 2012-06-29 P. Maletinsky , S. Hong , M. S. Grinolds , B. Hausmann , M. D. Lukin , R. -L. Walsworth , M. Loncar , A. Yacoby

We have designed and implemented a straightforward method to deterministically measure the temperature of the selected segment of a cold atom ensemble, and we have also developed an upgrade in the form of nondestructive thermometry. The…

Atomic Physics · Physics 2020-08-19 Xin Wang , Yuan Sun , Hua-Dong Cheng , Jin-Yin Wan , Yan-Ling Meng , Ling Xiao , Liang Liu

``Oversimplified'' and ``simplified'' methods based on true coincidence summing effect used in uncomplicated determination of the photo-peak efficiency of the semiconductor High Purity Germanium (HPGe) detector system are suggested and…

Instrumentation and Detectors · Physics 2022-06-22 Victor V. Golovko

We introduce and experimentally implement a method for the absolute detector calibration of photon-number-resolving time-bin multiplexing layouts based on the measured click statistics of superconduncting nanowire detectors. In particular,…

Quantum Physics · Physics 2017-03-10 Martin Bohmann , Regina Kruse , Jan Sperling , Christine Silberhorn , Werner Vogel

IceCube-DeepCore is a compact Cherenkov detector located in the clear ice of the bottom center of the IceCube Neutrino Telescope. Its purpose is to enhance the sensitivity of IceCube for low neutrino energies (< 1 TeV) and to lower the…

Instrumentation and Methods for Astrophysics · Physics 2019-08-13 Christopher Wiebusch

Standard deviation measurements of intensity profiles of stationary single fluorescent molecules are useful for studying axial localization, molecular orientation, and a fluorescence imaging system's spatial resolution. Here we report on…

Quantitative Methods · Quantitative Biology 2015-05-13 Michael C. DeSantis , Shawn H. DeCenzo , Je-Luen Li , Y. M. Wang

The next galactic supernova presents a once-in-a-lifetime opportunity to obtain detailed information about the explosion of a star and the extreme conditions found within its core. A core-collapse supernova will produce a neutrino burst…

High Energy Astrophysical Phenomena · Physics 2021-07-20 Spencer Griswold

Quantum metrology exploits quantum resources to enhance measurement precision beyond the classical limit. Conventional protocols normally rely on the preparation of delicate quantum states to acquire these resources, posing a major…

Quantum Physics · Physics 2026-03-31 Yuan Liu , Ke-Mi Xu , Hong-Bo Sun , Linhan Lin

An experimental continuous-wave (cw) pump-probe scheme is demonstrated by investigating the population and photoionization dynamics of an atomic system. Specifically, $^6$Li atoms are initially prepared in optically pumped $2^{2}S_{1/2}$…

Microwave devices capable of near-quantum-limited signal processing are essential components in the toolbox of solid-state quantum technologies. The manipulation and readout of single-photon microwave signals through amplifiers, mixers,…

The ICARUS T600 LAr TPC is the far detector of the Short Baseline Program at FNAL. As it will have to work at shallow depth in the Booster Neutrino Beam, a large cosmic rays background ($\sim 11$ kHz) will be present. To reduce it, precise…

Instrumentation and Detectors · Physics 2020-06-24 M. Bonesini , R. Benocci , R. Bertoni , A. Falcone , R. Mazza , M. Torti , A. Menegolli , G. L. Raselli , M. Rossella

Quantum dots must be tuned precisely to provide a suitable basis for quantum computation. A scalable platform for quantum computing can only be achieved by fully automating the tuning process. One crucial step is to trap the appropriate…

Mesoscale and Nanoscale Physics · Physics 2025-08-12 Fabian Hader , Sarah Fleitmann , Jan Vogelbruch , Lotte Geck , Stefan van Waasen
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