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Related papers: Burrows-Wheeler transform for terabases

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Modern genomic analyses increasingly rely on pangenomes, that is, representations of the genome of entire populations. The simplest representation of a pangenome is a set of individual genome sequences. Compared to e.g. sequence graphs,…

Genomics · Quantitative Biology 2025-11-25 Jannik Olbrich , Enno Ohlebusch

The Extended Burrows Wheeler transform (EBWT) helps to find the distance between two sequences. Implementation of an existing algorithm takes considerable amount of time for small size sequences. In this paper, we give a parallel…

Distributed, Parallel, and Cluster Computing · Computer Science 2011-02-02 Shashank Srikant

We investigate properties of the bijective Burrows-Wheeler transform (BBWT). We show that for any string $w$, a bidirectional macro scheme of size $O(r_B)$ can be induced from the BBWT of $w$, where $r_B$ is the number of maximal character…

Data Structures and Algorithms · Computer Science 2024-08-20 Golnaz Badkobeh , Hideo Bannai , Dominik Köppl

The run-length compressed Burrows-Wheeler transform (RLBWT) used in conjunction with the backward search introduced in the FM index is the centerpiece of most compressed indexes working on highly-repetitive data sets like biological…

Data Structures and Algorithms · Computer Science 2021-10-05 Jin Jie Deng , Wing-Kai Hon , Dominik Köppl , Kunihiko Sadakane

Indexing highly repetitive strings (i.e., strings with many repetitions) for fast queries has become a central research topic in string processing, because it has a wide variety of applications in bioinformatics and natural language…

Data Structures and Algorithms · Computer Science 2021-04-19 Takaaki Nishimoto , Yasuo Tabei

We show how to merge two run-length compressed Burrows-Wheeler Transforms (RLBWTs) into a run-length compressed extended Burrows-Wheeler Transform (eBWT) in $O (r)$ space and $O ((r + L) \log (m + n))$ time, where $m$ and $n$ are the…

Data Structures and Algorithms · Computer Science 2026-04-16 Travis Gagie

Until recently, most experts would probably have agreed we cannot backwards-step in constant time with a run-length compressed Burrows-Wheeler Transform (RLBWT), since doing so relies on rank queries on sparse bitvectors and those inherit…

Data Structures and Algorithms · Computer Science 2022-07-15 Nathaniel K. Brown , Travis Gagie , Massimiliano Rossi

Motivation: High-coverage sequencing data have significant, yet hard to exploit, redundancy. Most FASTQ compressors cannot efficiently compress the DNA stream of large datasets, since the redundancy between overlapping reads cannot be…

Data Structures and Algorithms · Computer Science 2014-09-19 Szymon Grabowski , Sebastian Deorowicz , Łukasz Roguski

Recently, Holt and McMillan [Bionformatics 2014, ACM-BCB 2014] have proposed a simple and elegant algorithm to merge the Burrows-Wheeler transforms of a family of strings. In this paper we show that the H&M algorithm can be improved so…

Data Structures and Algorithms · Computer Science 2016-09-16 Giovanni Manzini

We survey the different methods used for extending the BWT to collections of strings, following largely [Cenzato and Lipt\'ak, CPM 2022, Bioinformatics 2024]. We analyze the specific aspects and combinatorial properties of the resulting BWT…

Data Structures and Algorithms · Computer Science 2025-06-03 Davide Cenzato , Zsuzsanna Lipták , Nadia Pisanti , Giovanna Rosone , Marinella Sciortino

We study how the application of injective morphisms affects the number $r$ of equal-letter runs in the Burrows-Wheeler Transform (BWT). This parameter has emerged as a key repetitiveness measure in compressed indexing. We focus on the…

Formal Languages and Automata Theory · Computer Science 2025-04-25 Gabriele Fici , Giuseppe Romana , Marinella Sciortino , Cristian Urbina

We show how to build several data structures of central importance to string processing, taking as input the Burrows-Wheeler transform (BWT) and using small extra working space. Let $n$ be the text length and $\sigma$ be the alphabet size.…

Data Structures and Algorithms · Computer Science 2019-08-14 Nicola Prezza , Giovanna Rosone

While short read aligners, which predominantly use the FM-index, are able to easily index one or a few human genomes, they do not scale well to indexing databases containing thousands of genomes. To understand why, it helps to examine the…

Data Structures and Algorithms · Computer Science 2018-11-19 Alan Kuhnle , Taher Mun , Christina Boucher , Travis Gagie , Ben Langmead , Giovanni Manzini

The compression of highly repetitive strings (i.e., strings with many repetitions) has been a central research topic in string processing, and quite a few compression methods for these strings have been proposed thus far. Among them, an…

Data Structures and Algorithms · Computer Science 2022-02-17 Takaaki Nishimoto , Shunsuke Kanda , Yasuo Tabei

In many scientific and engineering applications, one has to solve not one but a sequence of instances of the same problem. Often times, the problems in the sequence are linked in a way that allows intermediate results to be reused. A…

Mathematical Software · Computer Science 2013-05-01 Diego Fabregat-Traver , Paolo Bientinesi

Mantaci et al. [TCS 2007] defined the eBWT to extend the definition of the BWT to a collection of strings, however, since this introduction, it has been used more generally to describe any BWT of a collection of strings and the fundamental…

Data Structures and Algorithms · Computer Science 2021-06-22 Christina Boucher , Davide Cenzato , Zsuzsanna Lipták , Massimiliano Rossi , Marinella Sciortino

Compressed suffix arrays (CSAs) index large repetitive collections and are key in many text applications. The r-index and its derivatives combine the run-length Burrows-Wheeler Transform (BWT) with suffix array sampling to achieve space…

Data Structures and Algorithms · Computer Science 2026-02-20 Diego Díaz-Domínguez , Veli Mäkinen

In this paper, we consider the problem of compressing a trie while supporting the powerful \emph{locate} queries: to return the pre-order identifiers of all nodes reached by a path labeled with a given query pattern. Our result builds on…

Data Structures and Algorithms · Computer Science 2020-12-18 Nicola Prezza

Given a string of characters, the Burrows-Wheeler Transform rearranges the characters in it so as to produce another string of the same length which is more amenable to compression techniques such as move to front, run-length encoding, and…

Data Structures and Algorithms · Computer Science 2012-01-17 Joseph Yossi Gil , David Allen Scott

We propose algorithms that, given the input string of length $n$ over integer alphabet of size $\sigma$, construct the Burrows-Wheeler transform (BWT), the permuted longest-common-prefix (PLCP) array, and the LZ77 parsing in…

Data Structures and Algorithms · Computer Science 2020-12-09 Dominik Kempa