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Understanding how distributed brain regions coordinate to produce behavior requires models that are both predictive and interpretable. We introduce Behavior-Adaptive Connectivity Estimation (BACE), an end-to-end framework that learns…

Neurons and Cognition · Quantitative Biology 2025-10-27 Mehrnaz Asadi , Sina Javadzadeh , Rahil Soroushmojdehi , S. Alireza Seyyed Mousavi , Terence D. Sanger

The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Latent space models have been widely adopted in modeling network data. Developing statistical inference for estimated model parameters enables quantifying associated uncertainty and is pivotal for downstream tasks. Despite recent progress…

Statistics Theory · Mathematics 2026-05-12 Yuang Tian , Jiajin Sun , Yinqiu He

This work considers a continuous framework to characterize the population-level variability of structural connectivity. Our framework assumes the observed white matter fiber tract endpoints are driven by a latent random function defined…

Computation · Statistics 2022-07-19 William Consagra , Martin Cole , Zhengwu Zhang

The application of graph theory to model the complex structure and function of the brain has shed new light on its organization and function, prompting the emergence of network neuroscience. Despite the tremendous progress that has been…

Signal Processing · Electrical Eng. & Systems 2020-09-29 Giulia Lioi , Vincent Gripon , Abdelbasset Brahim , François Rousseau , Nicolas Farrugia

Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Current concepts of neural networks have emerged over two centuries of progress beginning with the neural doctrine to the idea of neural cell assemblies. Presently the model of neural networks involves distributed neural circuits of nodes,…

Neurons and Cognition · Quantitative Biology 2024-07-30 M. Ram Murty , A. Narayan Prasad

We study simultaneous inference for multiple matrix-variate Gaussian graphical models in high-dimensional settings. Such models arise when spatiotemporal data are collected across multiple sample groups or experimental sessions, where each…

Methodology · Statistics 2026-01-21 Zongge Liu , Heejong Bong , Zhao Ren , Matthew A. Smith , Robert E. Kass

In this paper, we propose a new spectral-based approach to hypothesis testing for populations of networks. The primary goal is to develop a test to determine whether two given samples of networks come from the same random model or…

Methodology · Statistics 2020-11-26 Li Chen , Nathaniel Josephs , Lizhen Lin , Jie Zhou , Eric D. Kolaczyk

Exponential random graph models (ERGMs), also known as p* models, have been utilized extensively in the social science literature to study complex networks and how their global structure depends on underlying structural components. However,…

Applications · Statistics 2015-05-19 Sean L. Simpson , Satoru Hayasaka , Paul J. Laurienti

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure--function issue, treating a system of Jansen--Rit neural-mass…

Neurons and Cognition · Quantitative Biology 2020-07-10 Michael Forrester , Stephen Coombes , Jonathan J. Crofts , Stamatios N. Sotiropoulos , Reuben D. O'Dea

The global functional brain network (graph) is more suitable for characterizing brain states than local analysis of the connectivity of brain regions. Therefore, graph-theoretic approaches are the natural methods to study the brain.…

Topological data analysis (TDA) approaches are becoming increasingly popular for studying the dependence patterns in multivariate time series data. In particular, various dependence patterns in brain networks may be linked to specific tasks…

Methodology · Statistics 2023-12-04 Anass B. El-Yaagoubi , Hernando Ombao

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

We develop a new modeling framework for Inter-Subject Analysis (ISA). The goal of ISA is to explore the dependency structure between different subjects with the intra-subject dependency as nuisance. It has important applications in…

Methodology · Statistics 2017-09-22 Cong Ma , Junwei Lu , Han Liu

This paper presents a comprehensive and quality collection of functional human brain network data for potential research in the intersection of neuroscience, machine learning, and graph analytics. Anatomical and functional MRI images have…

Effective connectivity analysis provides an understanding of the functional organization of the brain by studying how activated regions influence one other. We propose a nonparametric Bayesian approach to model effective connectivity…

Applications · Statistics 2011-07-22 Sourabh Bhattacharya , Ranjan Maitra

Detecting and evaluating regions of brain under various circumstances is one of the most interesting topics in computational neuroscience. However, the majority of the studies on detecting communities of a functional connectivity network of…

Social and Information Networks · Computer Science 2018-06-04 Keivan Hassani Monfared , Kris Vasudevan , Jordan S. Farrell , G. Campbell Teskey

Brain function and connectivity is a pressing mystery in medicine related to many diseases. Neural connectomes have been studied as graphs with graph theory methods including topological methods. Work has started on hypergraph models and…

Methodology · Statistics 2022-05-09 Michael G. Rawson
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