Related papers: A Nonparametric Significance Test for Sampled Netw…
All networks can be analyzed at multiple scales. A higher scale of a network is made up of macro-nodes: subgraphs that have been grouped into individual nodes. Recasting a network at higher scales can have useful effects, such as decreasing…
Practical problems with missing data are common, and statistical methods have been developed concerning the validity and/or efficiency of statistical procedures. On a central focus, there have been longstanding interests on the mechanism…
Genes have specific functional roles, however, since they are dependent on each other, they can play a structural role within a network structure of their interactions. In this study, we analyze the structure of the gene interaction network…
Identifying interactions between proteins is important to understand underlying biological processes. Extracting a protein-protein interaction (PPI) from the raw text is often very difficult. Previous supervised learning methods have used…
We study the problems of sequential nonparametric two-sample and independence testing. Sequential tests process data online and allow using observed data to decide whether to stop and reject the null hypothesis or to collect more data,…
This paper studies the minimum observability of probabilistic Boolean networks (PBNs), the main objective of which is to add the fewest measurements to make an unobservable PBN become observable. First of all, the algebraic form of a PBN is…
Neural networks are powerful predictive models, but they provide little insight into the nature of relationships between predictors and outcomes. Although numerous methods have been proposed to quantify the relative contributions of input…
The ever increasing availability of data demands for techniques to extract relevant information from complex interacting systems, which can often be represented as weighted networks. In recent years, a number of approaches have been…
The study of multi-type Protein-Protein Interaction (PPI) is fundamental for understanding biological processes from a systematic perspective and revealing disease mechanisms. Existing methods suffer from significant performance degradation…
Network models are widely used to represent relational information among interacting units and the structural implications of these relations. Recently, social network studies have focused a great deal of attention on random graph models of…
A major issue in biology is the understanding of the interactions between proteins. These interactions can be described by a network, where the proteins are modeled by nodes and the interactions by edges. The origin of these protein…
Model checking plays an important role in linear regression as model misspecification seriously affects the validity and efficiency of regression analysis. In practice, model checking is often performed by subjectively evaluating the plot…
We consider testing the significance of a subset of covariates in a nonparametric regression. These covariates can be continuous and/or discrete. We propose a new kernel-based test that smoothes only over the covariates appearing under the…
We propose a method for obtaining parsimonious decompositions of networks into higher order interactions which can take the form of arbitrary motifs.The method is based on a class of analytically solvable generative models, where vertices…
We consider the problem of testing whether a graph's degree distribution belongs to a particular family, such as poisson or scale-free, given that we only observe a sampled subgraph. In particular, we focus on induced subgraph sampling, a…
Network data are increasingly collected along with other variables of interest. Our motivation is drawn from neurophysiology studies measuring brain connectivity networks for a sample of individuals along with their membership to a low or…
Testing network effects in weighted directed networks is a foundational problem in econometrics, sociology, and psychology. Yet, the prevalent edge dependency poses a significant methodological challenge. Most existing methods are…
In data science, determining proximity between observations is critical to many downstream analyses such as clustering, information retrieval and classification. However, when the underlying structure of the data probability space is…
Ranking nodes in networks according to a defined measure of importance is an extensively studied task, with applications in ecology, economic trade networks, and social networks. This paper introduces a method based on a non-linear…
Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…