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All networks can be analyzed at multiple scales. A higher scale of a network is made up of macro-nodes: subgraphs that have been grouped into individual nodes. Recasting a network at higher scales can have useful effects, such as decreasing…

Social and Information Networks · Computer Science 2022-02-18 Ross Griebenow , Brennan Klein , Erik Hoel

Practical problems with missing data are common, and statistical methods have been developed concerning the validity and/or efficiency of statistical procedures. On a central focus, there have been longstanding interests on the mechanism…

Methodology · Statistics 2020-03-26 Rui Duan , C. Jason Liang , Pamela Shaw , Cheng Yong Tang , Yong Chen

Genes have specific functional roles, however, since they are dependent on each other, they can play a structural role within a network structure of their interactions. In this study, we analyze the structure of the gene interaction network…

Biological Physics · Physics 2022-02-15 Nastaran Allahyari , Ali Hosseiny , Nima Abedpour , G. Reza Jafari

Identifying interactions between proteins is important to understand underlying biological processes. Extracting a protein-protein interaction (PPI) from the raw text is often very difficult. Previous supervised learning methods have used…

Quantitative Methods · Quantitative Biology 2018-08-10 Mahtab Ahmed , Jumayel Islam , Muhammad Rifayat Samee , Robert E. Mercer

We study the problems of sequential nonparametric two-sample and independence testing. Sequential tests process data online and allow using observed data to decide whether to stop and reject the null hypothesis or to collect more data,…

Machine Learning · Statistics 2023-07-21 Aleksandr Podkopaev , Aaditya Ramdas

This paper studies the minimum observability of probabilistic Boolean networks (PBNs), the main objective of which is to add the fewest measurements to make an unobservable PBN become observable. First of all, the algebraic form of a PBN is…

Systems and Control · Electrical Eng. & Systems 2024-01-24 Jiayi Xu , Shihua Fu , Liyuan Xia , Jianjun Wang

Neural networks are powerful predictive models, but they provide little insight into the nature of relationships between predictors and outcomes. Although numerous methods have been proposed to quantify the relative contributions of input…

Methodology · Statistics 2023-01-30 Francesca Mandel , Ian Barnett

The ever increasing availability of data demands for techniques to extract relevant information from complex interacting systems, which can often be represented as weighted networks. In recent years, a number of approaches have been…

Physics and Society · Physics 2019-02-19 Riccardo Marcaccioli , Giacomo Livan

The study of multi-type Protein-Protein Interaction (PPI) is fundamental for understanding biological processes from a systematic perspective and revealing disease mechanisms. Existing methods suffer from significant performance degradation…

Machine Learning · Computer Science 2021-06-02 Guofeng Lv , Zhiqiang Hu , Yanguang Bi , Shaoting Zhang

Network models are widely used to represent relational information among interacting units and the structural implications of these relations. Recently, social network studies have focused a great deal of attention on random graph models of…

Applications · Statistics 2010-10-06 Mark S. Handcock , Krista J. Gile

A major issue in biology is the understanding of the interactions between proteins. These interactions can be described by a network, where the proteins are modeled by nodes and the interactions by edges. The origin of these protein…

Biological Physics · Physics 2011-08-01 Christian M. Schneider , Lucilla de Arcangelis , Hans J. Herrmann

Model checking plays an important role in linear regression as model misspecification seriously affects the validity and efficiency of regression analysis. In practice, model checking is often performed by subjectively evaluating the plot…

Statistics Theory · Mathematics 2019-11-19 Rok Blagus , Jakob Peterlin , Janez Stare

We consider testing the significance of a subset of covariates in a nonparametric regression. These covariates can be continuous and/or discrete. We propose a new kernel-based test that smoothes only over the covariates appearing under the…

Statistics Theory · Mathematics 2014-03-28 Pascal Lavergne , Samuel Maistre , Valentin Patilea

We propose a method for obtaining parsimonious decompositions of networks into higher order interactions which can take the form of arbitrary motifs.The method is based on a class of analytically solvable generative models, where vertices…

Social and Information Networks · Computer Science 2024-04-03 Anatol E. Wegner , Sofia C. Olhede

We consider the problem of testing whether a graph's degree distribution belongs to a particular family, such as poisson or scale-free, given that we only observe a sampled subgraph. In particular, we focus on induced subgraph sampling, a…

Methodology · Statistics 2017-10-16 Robert Garrard

Network data are increasingly collected along with other variables of interest. Our motivation is drawn from neurophysiology studies measuring brain connectivity networks for a sample of individuals along with their membership to a low or…

Methodology · Statistics 2018-09-11 Daniele Durante , David B. Dunson

Testing network effects in weighted directed networks is a foundational problem in econometrics, sociology, and psychology. Yet, the prevalent edge dependency poses a significant methodological challenge. Most existing methods are…

Methodology · Statistics 2024-01-09 Wenqin Du , Yuan Zhang , Wen Zhou

In data science, determining proximity between observations is critical to many downstream analyses such as clustering, information retrieval and classification. However, when the underlying structure of the data probability space is…

Machine Learning · Statistics 2019-09-20 Divyansh Agarwal , Nancy R. Zhang

Ranking nodes in networks according to a defined measure of importance is an extensively studied task, with applications in ecology, economic trade networks, and social networks. This paper introduces a method based on a non-linear…

Statistical Mechanics · Physics 2025-04-01 Andrea Mazzolini , Michele Caselle , Matteo Osella

Retrieving gene functional networks from knowledge databases presents a challenge due to the mismatch between disease networks and subtype-specific variations. Current solutions, including statistical and deep learning methods, often fail…

Machine Learning · Computer Science 2025-02-25 Ziwei Yang , Zheng Chen , Xin Liu , Rikuto Kotoge , Peng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun
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