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Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…

Applications · Statistics 2021-11-12 William Consagra , Arun Venkataraman , Zhengwu Zhang

Tract-specific diffusion measures, as derived from brain diffusion MRI, have been linked to white matter tract structural integrity and neurodegeneration. As a consequence, there is a large interest in the automatic segmentation of white…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Bo Li , Marius de Groot , Meike Vernooij , Arfan Ikram , Wiro Niessen , Esther Bron

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu

This paper introduces TopoDiffuser, a diffusion-based framework for multimodal trajectory prediction that incorporates topometric maps to generate accurate, diverse, and road-compliant future motion forecasts. By embedding structural cues…

Robotics · Computer Science 2025-08-04 Zehui Xu , Junhui Wang , Yongliang Shi , Chao Gao , Guyue Zhou

Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…

While diffusion models excel at generating continuous data such as images, adapting them to discrete tasks has relied on indirect approaches that either operate in continuous embedding spaces or use token masking mechanisms, both of which…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xiao Li , Jiaqi Zhang , Shuxiang Zhang , Tianshui Chen , Liang Lin , Guangrun Wang

We develop a flexible framework for modeling high-dimensional imaging data observed longitudinally. The approach decomposes the observed variability of repeatedly measured high-dimensional observations into three additive components: a…

This paper presents DDTracking, a novel deep generative framework for diffusion MRI tractography that formulates streamline propagation as a conditional denoising diffusion process. In DDTracking, we introduce a dual-pathway encoding…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Yijie Li , Wei Zhang , Xi Zhu , Ye Wu , Yogesh Rathi , Lauren J. O'Donnell , Fan Zhang

The understanding of neurodegenerative diseases undoubtedly passes through the study of human brain white matter fiber tracts. To date, diffusion magnetic resonance imaging (dMRI) is the unique technique to obtain information about the…

Machine Learning · Computer Science 2012-07-04 Romain Giot , Christophe Charrier , Maxime Descoteaux

Purpose: Biophysical tissue models are increasingly used in the interpretation of diffusion MRI (dMRI) data, with the potential to provide specific biomarkers of brain microstructural changes. However, the general Standard Model has…

Biological Physics · Physics 2019-03-19 Santiago Coelho , Jose M. Pozo , Sune N. Jespersen , Derek K. Jones , Alejandro F. Frangi

Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of AD. However, classification performance obtained with different approaches is…

Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Jongyeon Yoon , Elyssa M. McMaster , Michael E. Kim , Gaurav Rudravaram , Kurt G. Schilling , Bennett A. Landman , Daniel Moyer

Transport processes are ubiquitous. They are, for example, at the heart of optical flow approaches; or of perfusion imaging, where blood transport is assessed, most commonly by injecting a tracer. An advection-diffusion equation is widely…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Peirong Liu , Lin Tian , Yubo Zhang , Stephen R. Aylward , Yueh Z. Lee , Marc Niethammer

Tracking microsctructural changes in the developing brain relies on accurate inter-subject image registration. However, most methods rely on either structural or diffusion data to learn the spatial correspondences between two or more…

Image and Video Processing · Electrical Eng. & Systems 2020-05-15 Irina Grigorescu , Alena Uus , Daan Christiaens , Lucilio Cordero-Grande , Jana Hutter , A. David Edwards , Joseph V. Hajnal , Marc Modat , Maria Deprez

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in micro-structure imaging and…

Accurate segmentation of ischemic stroke lesions from diffusion magnetic resonance imaging (MRI) is essential for clinical decision-making and outcome assessment. Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-24 Muhammad Usman , Azka Rehman , Muhammad Mutti Ur Rehman , Abd Ur Rehman , Muhammad Umar Farooq

Brain network analysis plays a crucial role in diagnosing and monitoring neurodegenerative disorders such as Alzheimer's disease (AD). Existing approaches for constructing structural brain networks from diffusion tensor imaging (DTI) often…

Neurons and Cognition · Quantitative Biology 2025-05-30 Xuhang Chen , Michael Kwok-Po Ng , Kim-Fung Tsang , Chi-Man Pun , Shuqiang Wang

Statistical analysis of Diffusion Tensor Imaging (DTI) data requires a computational framework that is both numerically tractable (to account for the high dimensional nature of the data) and geometric (to account for the nonlinear nature of…

Computer Vision and Pattern Recognition · Computer Science 2012-10-11 Anne Collard , Silvère Bonnabel , Christophe Phillips , Rodolphe Sepulchre