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We propose a travelling-wave perturbation method to control the spatiotemporal dynamics in a cardiac model. It is numerically demonstrated that the method can successfully suppress the wave instability (alternans in action potential…

Tissues and Organs · Quantitative Biology 2009-11-10 Peng-Ye Wang , Ping Xie , Hua-Wei Yin

The knowledge of transitions between regular, laminar or chaotic behavior is essential to understand the underlying mechanisms behind complex systems. While several linear approaches are often insufficient to describe such processes, there…

Medical Physics · Physics 2007-05-23 N. Marwan , N. Wessel , U. Meyerfeldt , A. Schirdewan , J. Kurths

There has been considerable efforts to understand the underlying complex dynamics in physiological time series. Methods originated from statistical physics revealed a non-Gaussian statistics and long range correlations in those signals.…

Neurons and Cognition · Quantitative Biology 2016-03-02 C. E. C. Galhardo , B. C. Coutinho , T. J. P. Penna , M. A. de Menezes , P. P. S. Soares

Pulse-coupled systems such as spiking neural networks exhibit nontrivial invariant sets in the form of attracting yet unstable saddle periodic orbits where units are synchronized into groups. Heteroclinic connections between such orbits may…

Adaptation and Self-Organizing Systems · Physics 2020-11-03 Fabio Schittler Neves , Marc Timme

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

Numerical Analysis · Mathematics 2022-08-12 Michele Bucelli , Alberto Zingaro , Pasquale Claudio Africa , Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

Autonomic nervous system is important for cardiac function regulation. Modeling of autonomic cardiac regulation can contribute to health tracking and disease management. This study proposed a mathematical model that simulates autonomic…

Medical Physics · Physics 2024-08-28 Runwei Lin , Frank Halfwerk , Dirk Donker , Gozewijn Dirk Laverman , Ying Wang

We investigate the relationship between the blood flow velocities (BFV) in the middle cerebral arteries and beat-to-beat blood pressure (BP) recorded from a finger in healthy and post-stroke subjects during the quasi-steady state after…

Biological Physics · Physics 2007-05-23 Zhi Chen , Kun Hu , H. Eugene Stanley , Vera Novak , Plamen Ch. Ivanov

The spatio-temporal dynamics of the deformation of a vibrated plate is measured by a high speed Fourier transform profilometry technique. The space-time Fourier spectrum is analyzed. It displays a behavior consistent with the premises of…

Chaotic Dynamics · Physics 2011-07-13 Nicolas Mordant

A method is proposed to analyze the heartbeat waveform that can yield a reliable characterization of the structure after only a few pulses. The measure suggested is entropy index that is related to the one found effective in describing…

Medical Physics · Physics 2007-05-23 Rudolph C. Hwa

There has been a long history in electrical muscle stimulation (EMS), which has been used for medical and interaction purposes. Human-computer interaction (HCI) researchers are now working on various applications, including virtual reality…

Human-Computer Interaction · Computer Science 2019-02-11 Michinari Kono , Jun Rekimoto

Cardiac arrhythmias such as ventricular tachycardia (VT) or ventricular fibrillation (VF) are the leading cause of death in the industrialised world. There is a growing consensus that these arrhythmias arise because of the formation of…

Pattern Formation and Solitons · Physics 2007-05-23 T. K. Shajahan , Sitabhra Sinha , Rahul Pandit

A number of studies showed association of mental status with heart rate variability. This work discovered a feature of frequency structure of heart rate variability that is associated with mental readiness. In three independent groups of…

Tissues and Organs · Quantitative Biology 2010-05-07 V. Mukhin , V. Klimenko

Power spectral density is an accepted measure of heart rate variability. Two estimators of multifractal properties: Wavelet Transform Modulus Maxima and Multifractal Detrended Fluctuation Analysis are used to investigate multifractal…

Quantitative Methods · Quantitative Biology 2007-05-23 Danuta Makowiec , Aleksandra Dudkowska , Rafal Galaska , Andrzej Rynkiewicz

We present a phenomenological reduced-order model to capture the transition to thermoacoustic instability in turbulent combustors. The model is based on the framework of synchronization and considers the acoustic field and the unsteady heat…

Adaptation and Self-Organizing Systems · Physics 2022-06-14 Yue Weng , Vishnu R. Unni , R. I. Sujith , Abhishek Saha

Conventional methods for diagnosing Social Anxiety Disorder (SAD), such as clinical interviews and self-reported questionnaires, often face accessibility barriers and subjective biases, underscoring the need for objective physiological…

Human-Computer Interaction · Computer Science 2025-12-02 Nilesh Kumar Sahu , Snehil Gupta , Haroon R. Lone

Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…

This work is motivated by personalized digital twins based on observations and physical models for treatment and prevention of Hypertension. The models commonly used are simplification of the real process and the aim is to make inference…

Methodology · Statistics 2022-01-19 Michail Spitieris , Ingelin Steinsland , Emma Ingestrom

We developed a novel patient-specific computational model for the numerical simulation of ventricular electromechanics in patients with ischemic cardiomyopathy (ICM). This model reproduces the activity both in sinus rhythm (SR) and in…

Circadian clocks play a pivotal role in orchestrating numerous physiological and developmental events. Waveform shapes of the oscillations of protein abundances can be informative about the underlying biochemical processes of circadian…

Subcellular Processes · Quantitative Biology 2018-11-27 Hang-Hyun Jo , Yeon Jeong Kim , Jae Kyoung Kim , Mathias Foo , David E. Somers , Pan-Jun Kim

An ensemble of pulse-coupled phase-oscillators is thoroughly analysed in the presence of a mean-field coupling and a dispersion of their natural frequencies. In spite of the analogies with the Kuramoto setup, a much richer scenario is…

Chaotic Dynamics · Physics 2017-11-06 Ekkehard Ullner , Antonio Politi
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