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Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

Higher Order Spectral (HOS) analysis is often applied effectively to analyze many bio-medical signals to detect nonlinear and non-Gaussian processes. One of the most basic HOS methods is the bispectral estimation, which extracts the degree…

Medical Physics · Physics 2018-09-25 Yamini Kotriwar , Sneha Kachhara , K. P. Harikrishnan , G. Ambika

Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. The contraction and relaxation of left ventricle (LV) is the main driving force of blood circulation. Altered LV hemodynamics is believed to be associated with…

Medical Physics · Physics 2019-11-04 Fanwei Kong , Christoph Augustin , Kevin Sack , Shawn Shadden

A parasystole from a heart-transplant patient is analysed using a beat-to-beat RR interval time series obtained from an electrocardiogram (ECG). The dysrhythmia, resulting from the co-existence of two pacemakers, the sinus node and an…

Medical Physics · Physics 2007-05-23 M. Costa , I. R. Pimentel , T. Santiago , M. J. Rebocho , J. Melo , E. Ducla-Soares

This paper presents a robust method to monitor heart rate (HR) from BCG (Ballistocardiography) signal, which is acquired from the sensor embedded in a chair or a mattress. The proposed algorithm addresses the shortfalls in traditional Fast…

Signal Processing · Electrical Eng. & Systems 2018-09-11 Qingsong Xie , Guoxing Wang , Yong Lian

Despite the widespread diffusion of nonlinear methods for heart rate variability (HRV) analysis, the presence and the extent to which nonlinear dynamics contribute to short-term HRV is still controversial. This work aims at testing the…

The association between visit-to-visit systolic blood pressure variability and cardiovascular events has recently received a lot of attention in the cardiovascular literature. But blood pressure variability is usually estimated on a…

Applications · Statistics 2019-01-25 Jessica K. Barrett , Raphael Huille , Richard Parker , Yuichiro Yano , Michael Griswold

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

Background: It has been difficult to demonstrate circadian rhythm in the two parameters of heart rate turbulence, turbulence onset (TO) and turbulence slope (TS). Objective: To devise a new method for detecting circadian rhythm in noisy…

We investigate flow of incompressible fluid in a cylindrical tube with elastic walls. The radius of the tube may change along its length. The discussed problem is connected to the blood flow in large human arteries and especially to…

Fluid Dynamics · Physics 2015-09-30 Zlatinka I. Dimitrova

Mathematical models and numerical simulations offer a non-invasive way to explore cardiovascular phenomena, providing access to quantities that cannot be measured directly. In this study, we start with a one-dimensional multiscale blood…

Machine Learning · Computer Science 2026-04-09 Giulia Bertaglia , Raffaella Fiamma Cabini

Longitudinal monitoring of heart rate (HR) and heart rate variability (HRV) can aid in tracking cardiovascular diseases (CVDs), sleep quality, sleep disorders, and reflect autonomic nervous system activity, stress levels, and overall…

Signal Processing · Electrical Eng. & Systems 2024-12-20 Ruhan Yi , Mihail Popescu , James M. Keller , Grant Scott , Laurel Despins , David Heise , Marjorie Skubic

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

Ensembles of phase-oscillators are known to exhibit a variety of collective regimes. Here, we show that a simple mean-field model involving two heterogenous populations of pulse-coupled oscillators, exhibits, in the strong-coupling limit, a…

Disordered Systems and Neural Networks · Physics 2024-07-12 German Mato , Antonio Politi , Alessandro Torcini

The processing of ECG signal provides a wealth of information on cardiac function and overall cardiovascular health. While multi-lead ECG recordings are often necessary for a proper assessment of cardiac rhythms, they are not always…

Applications · Statistics 2016-11-23 Christophe L. Herry , Martin Frasch , Andrew JE Seely , Hau-tieng Wu

Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…

Computational Engineering, Finance, and Science · Computer Science 2025-08-04 Haizhou Yang , Jiyang Zhang , Ismael Z. Assi , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

A number of inhibitory and excitatory factors regulate the beating of the heart. Consequently, the inter-beat intervals (IBIs) are not constant but vary around a mean value, even in the absence of external factors like exercise or stress.…

Signal Processing · Electrical Eng. & Systems 2024-10-22 Ilker Bayram

Voltage-sensitive fluorescence imaging is widely used to image action potential waves in the heart. However, while the electrical waves trigger mechanical contraction, imaging needs to be performed with pharmacologically…

Medical Physics · Physics 2026-03-12 Shrey Chowdhary , Jan Lebert , Shai Dickman , Charles Gordon , Jan Christoph

The Electrocardiograph signal represents the heart's electrical activity while blood pressure results from the heart's mechanical activity. Previous studies have investigated how the heart's electrical and mechanical activities are related…

Signal Processing · Electrical Eng. & Systems 2020-08-25 Seyedeh Somayyeh Mousavi , Mostafa Charmi , Mohammad Firouzmand , Mohammad Hemmati , Maryam Moghadam , Yadollah Ghorbani