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We consider a general class of stochastic networks and ask which network nodes need to be controlled, and how, to stabilize and switch between desired metastable (target) states in terms of the first and second statistical moments of the…

Adaptation and Self-Organizing Systems · Physics 2016-07-20 Dmytro Bielievtsov , Josef Ladenbauer , Klaus Obermayer

Nested structure, which is non-random, controls cooperation dynamics and biodiversity in plant-animal mutualistic networks. This structural pattern has been explained in a static (non-growth) network models. However, evolutionary processes…

Populations and Evolution · Quantitative Biology 2015-03-19 Kazuhiro Takemoto , Masanori Arita

Pinning control on complex dynamical networks has emerged as a very important topic in recent trends of control theory due to the extensive study of collective coupled behaviors and their role in physics, engineering and biology. In…

Optimization and Control · Mathematics 2016-01-25 Stephane Chretien , Sebastien Darses

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

Statistical Mechanics · Physics 2007-05-23 Min Liu , Kevin E. Bassler

Dynamic networks models describe a growing number of important scientific processes, from cell biology and epidemiology to sociology and finance. There are many aspects of dynamical networks that require statistical considerations. In this…

Methodology · Statistics 2012-05-15 E. C. Wit , A. Abbruzzo

Motivation: Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into…

Molecular Networks · Quantitative Biology 2016-10-04 David Murrugarra , Alan Veliz-Cuba , Boris Aguilar , Reinhard Laubenbacher

We investigated the properties of Boolean networks that follow a given reliable trajectory in state space. A reliable trajectory is defined as a sequence of states which is independent of the order in which the nodes are updated. We…

Biological Physics · Physics 2011-03-23 Tiago P. Peixoto , Barbara Drossel

Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are…

Molecular Networks · Quantitative Biology 2007-05-23 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

The complex dynamics of gene expression in living cells can be well-approximated using Boolean networks. The average sensitivity is a natural measure of stability in these systems: values below one indicate typically stable dynamics…

Molecular Networks · Quantitative Biology 2018-10-03 Bryan C. Daniels , Hyunju Kim , Douglas Moore , Siyu Zhou , Harrison Smith , Bradley Karas , Stuart A. Kauffman , Sara I. Walker

Network science has experienced unprecedented rapid development in the past two decades. The network perspective has also been widely applied to explore various complex systems in great depth. In the first decade, fundamental…

Physics and Society · Physics 2020-01-13 Aming Li , Yang-Yu Liu

The complexity of many biological, social and technological systems stems from the richness of the interactions among their units. Over the past decades, a great variety of complex systems has been successfully described as networks whose…

Biological phenomena differ significantly from physical phenomena. At the heart of this distinction is the fact that biological entities have computational abilities and thus they are inherently difficult to predict. This is the reason why…

Molecular Networks · Quantitative Biology 2009-09-29 Pau Fernandez , Ricard V. Sole

Regulatory networks (RNs) are a well-accepted modelling formalism in computational systems biology. The control of RNs is currently receiving a lot of attention because it provides a computational basis for cell reprogramming -- an…

Systems and Control · Electrical Eng. & Systems 2022-03-01 Luboš Brim , Samuel Pastva , David Šafránek , Eva Šmijáková

The controllability of networked sampled-data systems with zero-order holders on the control and transmission channels is explored, where single- and multi-rate sampling patterns are considered, respectively. The effects of sampling on the…

Systems and Control · Electrical Eng. & Systems 2023-02-28 Zixuan Yang , Xiaofan Wang , Lin Wang

With an increasing amount of observations on the dynamics of many complex systems, it is required to reveal the underlying mechanisms behind these complex dynamics, which is fundamentally important in many scientific fields such as climate,…

Neurons and Cognition · Quantitative Biology 2025-03-19 Zhendong Yu , Haiping Huang

A fundamental premise of statistical physics is that the particles in a physical system are interchangeable, and hence the state of each specific component is representative of the system as a whole. This assumption breaks down for complex…

Physics and Society · Physics 2025-12-16 Neil G. MacLaren , Baruch Barzel , Naoki Masuda

We investigate to what extent the degree sequence of a directed network constrains the number of driver nodes. We develop a pair of algorithms that take a directed degree sequence as input and aim to output a network with the maximum or…

Physics and Society · Physics 2020-03-24 Abdorasoul Ghasemi , Márton Pósfai , Raissa M. D'Souza

We consider the controllability of large-scale linear networked dynamical systems when complete knowledge of network structure is unavailable and knowledge is limited to coarse summaries. We provide conditions under which average…

Systems and Control · Electrical Eng. & Systems 2022-06-22 Nafiseh Ghoroghchian , Rajasekhar Anguluri , Gautam Dasarathy , Stark C. Draper

In a recent paper, it has been suggested that the controllability of a diffusively coupled complex network, subject to localized feedback loops at some of its vertices, can be assessed by means of a Master Stability Function approach, where…

Disordered Systems and Neural Networks · Physics 2007-08-09 Francesco Sorrentino
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