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Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

Let $S_b(n)$ denote the sum of the squares of the digits of the positive integer $n$ in base $b\geq2$. It is well-known that the sequence of iterates of $S_b(n)$ terminates in a fixed point or enters a cycle. Let $N=2n-1$, $n\geq2$. It is…

General Mathematics · Mathematics 2023-10-10 Walter A. Kehowski

In this paper we consider piecewise affine differential equations modeling gene networks. We work with arbitrary decay rates, and under a local hypothesis expressed as an alignment condition of successive focal points. The interaction graph…

Dynamical Systems · Mathematics 2009-03-12 Etienne Farcot , Jean-Luc Gouzé

We introduce a simple model of static networks, where nodes are located on a ring structure, and two accompanying dynamic rules of repeated averaging on periodic node states. We assume nodes can interact with neighbors, and will add…

Physics and Society · Physics 2012-03-16 Suhan Ree

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are…

Molecular Networks · Quantitative Biology 2007-05-23 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

We derive conditions for the existence of fixed points of cone mappings without assuming scalability of functions. Monotonicity and scalability are often inseparable in the literature in the context of searching for fixed points of…

Dynamical Systems · Mathematics 2022-09-09 Grzegorz Gabor , Krzysztof Rykaczewski

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2008-01-30 Winfried Just , German Enciso

Boolean networks can be viewed as functions on the set of binary strings of a given length, described via logical rules. They were introduced as dynamic models into biology, in particular as logical models of intracellular regulatory…

Dynamical Systems · Mathematics 2025-04-16 J. García Galofre , M. Pérez Millán , A. Galarza Rial , R. Laubenbacher , A. Dickenstein

In this paper, we address the formal characterization of targets triggering cellular trans-differentiation in the scope of Boolean networks with asynchronous dynamics. Given two fixed points of a Boolean network, we are interested in all…

Discrete Mathematics · Computer Science 2016-11-07 Hugues Mandon , Stefan Haar , Loïc Paulevé

The stability number of a graph G is the cardinality of a stability system of G (that is of a stable set of maximum size of G). A graph is alpha-stable if its stability number remains the same upon both the deletion and the addition of any…

Combinatorics · Mathematics 2007-05-23 Vadim E. Levit , Eugen Mandrescu

Automata networks can be seen as bare finite dynamical systems, but their growing theory has shown the importance of the underlying communication graph of such networks. This paper tackles the question of what dynamics can be realized up to…

Computational Complexity · Computer Science 2025-11-17 Julio Aracena , Florian Bridoux , Maximilien Gadouleau , Pierre Guillon , Kévin Perrot , Adrien Richard , Guillaume Theyssier

It is a common belief that the order of a Boolean network is mainly determined by its attractors, including fixed points and cycles. Using semi-tensor product (STP) of matrices and the algebraic state-space representation (ASSR) of Boolean…

Systems and Control · Electrical Eng. & Systems 2021-11-30 Xiao Zhang , Zhengping Ji , Daizhan Cheng

The abundance of data about social relationships allows the human behavior to be analyzed as any other natural phenomenon. Here we focus on balance theory, stating that social actors tend to avoid establishing cycles with an odd number of…

Physics and Society · Physics 2024-05-15 Anna Gallo , Diego Garlaschelli , Renaud Lambiotte , Fabio Saracco , Tiziano Squartini

Does the interaction graph of a finite dynamical system can force this system to have a "complex" dynamics ? In other words, given a finite interval of integers $A$, which are the signed digraphs $G$ such that every finite dynamical system…

Discrete Mathematics · Computer Science 2016-03-09 Maximilien Gadouleau , Adrien Richard

We study Boolean networks which are simple spatial models of the highly conserved Delta-Notch system. The models assume the inhibition of Delta in each cell by Notch in the same cell, and the activation of Notch in presence of Delta in…

Discrete Mathematics · Computer Science 2020-07-31 Elisa Tonello , Heike Siebert

Let $G$ be a graph and $f: G\rightarrow G$ be a continuous map. We establish a structure theorem which describes the structures of the set $R(f)-\overline{P(f)}$, where $R(f)$ and $P(f)$ are the recurrent point set and the periodic point…

Dynamical Systems · Mathematics 2023-10-31 Jiehua Mai , Enhui Shi , Kesong Yan , Fanping Zeng

A graph $H$ is said to be positive if the homomorphism density $t_H(G)$ is non-negative for all weighted graphs $G$. The positive graph conjecture proposes a characterisation of such graphs, saying that a graph is positive if and only if it…

Combinatorics · Mathematics 2024-04-29 David Conlon , Joonkyung Lee , Leo Versteegen

In 1996, in his last paper, Erd\H{o}s asked the following question that he formulated together with Faudree: is there a positive $c$ such that any $(n+1)$-regular graph $G$ on $2n$ vertices contains at least $c 2^{2n}$ distinct…

Combinatorics · Mathematics 2025-04-01 Nemanja Draganić , Peter Keevash , Alp Müyesser

For a directed graph $G$ without loops or parallel edges, let $\beta(G)$ denote the size of the smallest feedback arc set, i.e., the smallest subset $X \subset E(G)$ such that $G \sm X$ has no directed cycles. Let $\gamma(G)$ be the number…

Combinatorics · Mathematics 2008-09-29 Jacob Fox , Peter Keevash , Benny Sudakov

We discuss properties which must be satisfied by a genetic network in order for it to allow differentiation. These conditions are expressed as follows in mathematical terms. Let $F$ be a differentiable mapping from a finite dimensional real…

Molecular Networks · Quantitative Biology 2007-05-23 Christophe Soule