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Identifying the mutations that drive cancer growth is key in clinical decision making and precision oncology. As driver mutations confer selective advantage and thus have an increased likelihood of occurrence, frequency-based statistical…

Genomics · Quantitative Biology 2021-05-04 Adnan Akbar , Andrey Solovyev , John W Cassidy , Nirmesh Patel , Harry W Clifford

In this extended abstract, we report on ongoing work towards an approximate multimodal optimization algorithm with asymptotic guarantees. Multimodal optimization is the problem of finding all local optimal solutions (modes) to a path…

Robotics · Computer Science 2021-07-07 Andreas Orthey , Florian T. Pokorny , Marc Toussaint

We introduce PMODE (Partitioned Mixture Of Density Estimators), a general and modular framework for mixture modeling with both parametric and nonparametric components. PMODE builds mixtures by partitioning the data and fitting separate…

Machine Learning · Computer Science 2025-09-01 Robert A. Vandermeulen

The exploration of multimodal language models integrates multiple data types, such as images, text, language, audio, and other heterogeneity. While the latest large language models excel in text-based tasks, they often struggle to…

Artificial Intelligence · Computer Science 2023-11-23 Jiayang Wu , Wensheng Gan , Zefeng Chen , Shicheng Wan , Philip S. Yu

This paper proposes a state-machine model for a multi-modal, multi-robot environmental sensing algorithm. This multi-modal algorithm integrates two different exploration algorithms: (1) coverage path planning using variable formations and…

Multiagent Systems · Computer Science 2023-06-08 Vu Phi Tran , Asanka Perera , Matthew A. Garratt , Kathryn Kasmarik , Sreenatha Anavatti

Automated model discovery is the process of automatically searching and identifying the most appropriate model for a given dataset over a large combinatorial search space. Existing approaches, however, often face challenges in balancing the…

Artificial Intelligence · Computer Science 2025-10-01 Lee Jung-Mok , Nam Hyeon-Woo , Moon Ye-Bin , Junhyun Nam , Tae-Hyun Oh

We present a nonparametric method for selecting informative features in high-dimensional clustering problems. We start with a screening step that uses a test for multimodality. Then we apply kernel density estimation and mode clustering to…

Statistics Theory · Mathematics 2014-06-10 Larry Wasserman , Martin Azizyan , Aarti Singh

Multimodal learning, a rapidly evolving field in artificial intelligence, seeks to construct more versatile and robust systems by integrating and analyzing diverse types of data, including text, images, audio, and video. Inspired by the…

Artificial Intelligence · Computer Science 2024-12-24 Priyaranjan Pattnayak , Hitesh Laxmichand Patel , Bhargava Kumar , Amit Agarwal , Ishan Banerjee , Srikant Panda , Tejaswini Kumar

Unimodality constitutes a key property indicating grouping behavior of the data around a single mode of its density. We propose a method that partitions univariate data into unimodal subsets through recursive splitting around valley points…

Machine Learning · Computer Science 2024-12-23 Paraskevi Chasani , Aristidis Likas

In this paper, we present a dense hybrid proposal modulation (DHPM) method for lane detection. Most existing methods perform sparse supervision on a subset of high-scoring proposals, while other proposals fail to obtain effective shape and…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yuejian Wu , Linqing Zhao , Jiwen Lu , Haibin Yan

We study efficient importance sampling techniques for particle filtering (PF) when either (a) the observation likelihood (OL) is frequently multimodal or heavy-tailed, or (b) the state space dimension is large or both. When the OL is…

Information Theory · Computer Science 2011-04-13 Namrata Vaswani

Modern datasets often contain ballast as redundant or low-utility information that increases dimensionality, storage requirements, and computational cost without contributing meaningful analytical value. This study introduces a generalized,…

Machine Learning · Computer Science 2026-02-20 Yaroslav Solovko

Density Estimation is one of the central areas of statistics whose purpose is to estimate the probability density function underlying the observed data. It serves as a building block for many tasks in statistical inference, visualization,…

Machine Learning · Statistics 2019-04-02 Zhipeng Wang , David W. Scott

Utilizing long-range dependency, a concept extensively studied in homogeneous graphs, remains underexplored in heterogeneous graphs, especially on large ones, posing two significant challenges: Reducing computational costs while maximizing…

Artificial Intelligence · Computer Science 2025-03-26 Chao Li , Zijie Guo , Qiuting He , Hao Xu , Kun He

We address the problem of estimating multiple modes of a multivariate density using persistent homology, a central tool in Topological Data Analysis. We introduce a method based on the preliminary estimation of the $H_0$-persistence diagram…

Statistics Theory · Mathematics 2025-05-06 Hugo Henneuse

We introduce physics-informed multimodal autoencoders (PIMA) - a variational inference framework for discovering shared information in multimodal scientific datasets representative of high-throughput testing. Individual modalities are…

Machine Learning · Computer Science 2022-02-08 Nathaniel Trask , Carianne Martinez , Kookjin Lee , Brad Boyce

For data-constrained, complex and dynamic industrial environments, there is a critical need for transferable and multimodal methodologies to enhance anomaly detection and therefore, prevent costs associated with system failures. Typically,…

Biodiversity research requires complete and detailed information to study ecosystem dynamics at different scales. Employing data-driven methods like Machine Learning is getting traction in ecology and more specific biodiversity, offering…

Quantitative Methods · Quantitative Biology 2025-10-27 Stylianos Stasinos , Martino Mensio , Elena Lazovik , Athanasios Trantas

Scientific machine learning (SciML) increasingly requires models that capture multimodal conditional uncertainty arising from ill-posed inverse problems, multistability, and chaotic dynamics. While recent work has favored highly expressive…

Machine Learning · Computer Science 2026-02-03 Leonardo Ferreira Guilhoto , Akshat Kaushal , Paris Perdikaris

Mode clustering is a nonparametric method for clustering that defines clusters using the basins of attraction of a density estimator's modes. We provide several enhancements to mode clustering: (i) a soft variant of cluster assignment, (ii)…

Methodology · Statistics 2015-12-23 Yen-Chi Chen , Christopher R. Genovese , Larry Wasserman