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Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…

Neurons and Cognition · Quantitative Biology 2009-06-12 Eugenio Urdapilleta , Ines Samengo

In realistic neural circuits, both neurons and synapses are coupled in dynamics with separate time scales. The circuit functions are intimately related to these coupled dynamics. However, it remains challenging to understand the intrinsic…

Neurons and Cognition · Quantitative Biology 2025-11-11 Wenkang Du , Haiping Huang

Living systems implement and execute an extraordinary plethora of computational tasks. The inherent degree of large scale coordination emerges as a global property, from the intricate sea of microscopic interactions. The brain, with its…

Disordered Systems and Neural Networks · Physics 2018-01-03 Duccio Fanelli , Francesco Ginelli , Roberto Livi , Niccolò Zagli , Clement Zankoc

The dynamical responses of complex neuronal networks to external stimulus injected on a \emph{single} neuron are investigated. Stimulating the largest-degree neuron in the network, it is found that as the intensity of the stimulus…

Chaotic Dynamics · Physics 2016-04-13 Mengjiao Chen , Weijie Lin , Hengtong Wang , Wei Ren , Xingang Wang

In neural systems, synaptic plasticity is usually driven by spike trains. Due to the inherent noises of neurons, synapses and networks, spike trains typically exhibit externally uncontrollable variability such as spatial heterogeneity and…

Neurons and Cognition · Quantitative Biology 2015-06-18 Zedong Bi , Changsong Zhou , Hai-Jun Zhou

Brain function results from communication between neurons connected by complex synaptic networks. Synapses are themselves highly complex and diverse signaling machines, containing protein products of hundreds of different genes, some in…

Computer Vision and Pattern Recognition · Computer Science 2017-07-05 Anish K. Simhal , Cecilia Aguerrebere , Forrest Collman , Joshua T. Vogelstein , Kristina D. Micheva , Richard J. Weinberg , Stephen J. Smith , Guillermo Sapiro

The behaviour of neurons under the influence of periodic external input has been modelled very successfully by circle maps. The aim of this note is to extend certain aspects of this analysis to a much more general class of forcing…

Neurons and Cognition · Quantitative Biology 2009-03-27 T. Jaeger

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

We study the onset of synchronous states in realistic chaotic neurons coupled by mutually inhibitory chemical synapses. For the realistic parameters, namely the synaptic strength and the intrinsic current, this synapse introduces…

Statistical Mechanics · Physics 2015-05-13 T. Pereira , M. S. Baptista , J. Kurths , M. B. Reyes

We present experimental and theoretical arguments, at the single neuron level, suggesting that neuronal response fluctuations reflect a process that positions the neuron near a transition point that separates excitable and unexcitable…

Neurons and Cognition · Quantitative Biology 2013-12-25 Asaf Gal , Shimon Marom

Anticipation is a strategy used by neural fields to compensate for transmission and processing delays during the tracking of dynamical information, and can be achieved by slow, localized, inhibitory feedback mechanisms such as short-term…

Disordered Systems and Neural Networks · Physics 2015-08-07 C. C. Alan Fung , K. Y. Michael Wong , Hongzi Mao , Si Wu

The steady-state firing rate and firing-rate response of the leaky and exponential integrate-and-fire models receiving synaptic shot noise with excitatory and inhibitory reversal potentials is examined. For the particular case where the…

Neurons and Cognition · Quantitative Biology 2024-03-13 Magnus J E Richardson

Spiking neural network models characterize the emergent collective dynamics of circuits of biological neurons and help engineer neuro-inspired solutions across fields. Most dynamical systems' models of spiking neural networks typically…

Computational Physics · Physics 2023-04-12 Georg Börner , Fabio Schittler Neves , Marc Timme

Working memory requires the brain to maintain information from the recent past to guide ongoing behavior. Neurons can contribute to this capacity by slowly integrating their inputs over time, creating persistent activity that outlasts the…

Neurons and Cognition · Quantitative Biology 2025-11-20 Nicoas Zucchet , Qianqian Feng , Axel Laborieux , Friedemann Zenke , Walter Senn , João Sacramento

Balanced neural networks -- in which excitatory and inhibitory inputs compensate each other on average -- give rise to a dynamical phase dominated by fluctuations called asynchronous state, crucial for brain functioning. However, structural…

Statistical Mechanics · Physics 2024-03-05 Jorge Pretel , Victor Buendía , Joaquín J. Torres , Miguel A. Muñoz

The impact of inhibitory and excitatory synapses in delay-coupled Hodgkin--Huxley neurons that are driven by noise is studied. If both synaptic types are used for coupling, appropriately tuned delays in the inhibition feedback induce…

Neurons and Cognition · Quantitative Biology 2012-05-01 Qingyun Wang , Honghui Zhang , Matjaz Perc , Guanrong Chen

A classical view of neural coding relies on temporal firing synchrony among functional groups of neurons; however the underlying mechanism remains an enigma. Here we experimentally demonstrate a mechanism where time-lags among neuronal…

Neurons and Cognition · Quantitative Biology 2013-10-31 Roni Vardi , Amir Goldental , Shoshana Guberman , Alexander Kalmanovich , Hagar Marmari , Ido Kanter

Spontaneous brain activity in the absence of external stimuli is not random but contains complex dynamical structures such as neuronal avalanches with power-law duration and size distributions. These experimental observations have been…

Biological Physics · Physics 2024-12-04 Lik-Chun Chan , Tsz-Fung Kok , Emily S. C. Ching

Why do neurons communicate through spikes? By definition, spikes are all-or-none neural events which occur at continuous times. In other words, spikes are on one side binary, existing or not without further details, and on the other can…

Neurons and Cognition · Quantitative Biology 2024-04-12 Antoine Grimaldi , Amélie Gruel , Camille Besnainou , Jean-Nicolas Jérémie , Jean Martinet , Laurent U Perrinet

We study the dynamic range of a cellular automaton model for a neuronal network with electrical and chemical synapses. The neural network is separated into two layers, where one layer corresponds to inhibitory, and the other corresponds to…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 F. S. Borges , E. L. Lameu , A. M. Batista , K. C. Iarosz , M. S. Baptista , R. L. Viana