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A string $w$ is said to be a minimal absent word (MAW) for a string $S$ if $w$ does not occur in $S$ and any proper substring of $w$ occurs in $S$. We focus on non-trivial MAWs which are of length at least 2. Finding such non-trivial MAWs…

Data Structures and Algorithms · Computer Science 2024-05-21 Shunsuke Inenaga , Takuya Mieno , Hiroki Arimura , Mitsuru Funakoshi , Yuta Fujishige

A string $w$ is called a minimal absent word (MAW) for another string $T$ if $w$ does not occur (as a substring) in $T$ and any proper substring of $w$ occurs in $T$. State-of-the-art data structures for reporting the set $\mathsf{MAW}(T)$…

Data Structures and Algorithms · Computer Science 2022-04-18 Tooru Akagi , Kouta Okabe , Takuya Mieno , Yuto Nakashima , Shunsuke Inenaga

A string $w$ is called a minimal absent word (MAW) for a string $S$ if $w$ does not occur as a substring in $S$ and all proper substrings of $w$ occur in $S$. MAWs are well-studied combinatorial string objects that have potential…

Data Structures and Algorithms · Computer Science 2023-08-01 Kouta Okabe , Takuya Mieno , Yuto Nakashima , Shunsuke Inenaga , Hideo Bannai

An absent factor of a string $w$ is a string $u$ which does not occur as a contiguous substring (a.k.a. factor) inside $w$. We extend this well-studied notion and define absent subsequences: a string $u$ is an absent subsequence of a string…

Formal Languages and Automata Theory · Computer Science 2026-04-08 Maria Kosche , Tore Koß , Florin Manea , Stefan Siemer

A {\em subsequence} of a word $w$ is a word $u$ that can be obtained by deleting some letters from $w$ while maintaining the relative order of the remaining letters, e.g., $\mathtt{lala}$ is a subsequence of $\mathtt{alfalfa}$. A word, over…

Formal Languages and Automata Theory · Computer Science 2025-09-01 Duncan Adamson , Pamela Fleischmann , Annika Huch , Florin Manea , Paul Sarnighausen-Cahn , Max Wiedenhöft

We show that textual analysis of microbial genomes reveal telling footprints of the early evolution of the genomes. The frequencies of word occurrence of random DNA sequences considered as texts in their four nucleotides are expected to…

Biological Physics · Physics 2007-05-23 Li-Ching Hsieh , Liaofu Luo , HC Lee

Statistical analysis of distributions of occurrence frequencies of short words in 108 microbial complete genomes reveals the existence of a set of universal "root-sequence lengths" shared by all microbial genomes. These lengths and their…

Biological Physics · Physics 2007-05-23 Li-Ching Hsieh , Chang-Heng Chang , Liaofu Luo , Fengmin Ji , Hoong-Chien Lee

Statistical analysis of bacteria genomes texts has been performed on the basis of 20 complete genomes origin from Genebank. It has been revealed that the word ranked distributions are quite well approximated by logarithmic law. Results…

Condensed Matter · Physics 2009-10-31 Olga V. Kirillova

Given a string $w$, another string $v$ is said to be a subsequence of $w$ if $v$ can be obtained from $w$ by removing some of its letters; on the other hand, $v$ is called an absent subsequence of $w$ if $v$ is not a subsequence of $w$. The…

Data Structures and Algorithms · Computer Science 2025-05-01 Florin Manea , Tina Ringleb , Stefan Siemer , Maximilian Winkler

We extend the theory of minimal absent words to (rooted and unrooted) trees, having edges labeled by letters from an alphabet $\Sigma$ of cardinality $\sigma$. We show that the set $\text{MAW}(T)$ of minimal absent words of a rooted (resp.…

Data Structures and Algorithms · Computer Science 2019-10-31 Gabriele Fici , Paweł Gawrychowski

Modern genomic analyses increasingly rely on pangenomes, that is, representations of the genome of entire populations. The simplest representation of a pangenome is a set of individual genome sequences. Compared to e.g. sequence graphs,…

Genomics · Quantitative Biology 2025-11-25 Jannik Olbrich , Enno Ohlebusch

A minimal absent word of a sequence x, is a sequence yt hat is not a factorof x, but all of its proper factors are factors of x as well. The set of minimal absent words uniquely defines the sequence itself. In recent times minimal absent…

Formal Languages and Automata Theory · Computer Science 2021-06-01 Giuseppa Castiglione , Jia Gao , Sabrina Mantaci , Antonio Restivo

Genomes may be analyzed from an information viewpoint as very long strings, containing functional elements of variable length, which have been assembled by evolution. In this work an innovative information theory based algorithm is…

Genomics · Quantitative Biology 2020-09-23 Vincenzo Bonnici , Giuditta Franco , Vincenzo Manca

An absent word of a word y of length n is a word that does not occur in y. It is a minimal absent word if all its proper factors occur in y. Minimal absent words have been computed in genomes of organisms from all domains of life; their…

Data Structures and Algorithms · Computer Science 2014-07-01 Carl Barton , Alice Heliou , Laurent Mouchard , Solon P. Pissis

Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realized by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free…

Data Structures and Algorithms · Computer Science 2015-12-23 Maxime Crochemore , Gabriele Fici , Robert Mercaş , Solon P. Pissis

A string $w$ is called a minimal absent word (MAW) for another string $T$ if $w$ does not occur in $T$ but the proper substrings of $w$ occur in $T$. For example, let $\Sigma = \{\mathtt{a, b, c}\}$ be the alphabet. Then, the set of MAWs…

We propose that the distribution of DNA words in genomic sequences can be primarily characterized by a double Pareto-lognormal distribution, which explains lognormal and power-law features found across all known genomes. Such a distribution…

Genomics · Quantitative Biology 2007-05-23 Miklós Csűrös , Laurent Noé , Gregory Kucherov

We study here the so called subsequence pattern matching also known as hidden pattern matching in which one searches for a given pattern $w$ of length $m$ as a subsequence in a random text of length $n$. The quantity of interest is the…

Probability · Mathematics 2020-03-24 Svante Janson , Wojciech Szpankowski

Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realised by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free…

Data Structures and Algorithms · Computer Science 2018-06-08 Panagiotis Charalampopoulos , Maxime Crochemore , Gabriele Fici , Robert Mercas , Solon P. Pissis

Complexity metrics and machine learning (ML) models have been utilized to analyze the lengths of segmental genomic entities like: exons, introns, intergenic and repeat/unique DNA sequences, in each of the 22 human chromosomes. The purpose…

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