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The brain processes visual inputs having structure over a large range of spatial scales. The precise mechanisms or algorithms used by the brain to achieve this feat are largely unknown and an open problem in visual neuroscience. In…

Neurons and Cognition · Quantitative Biology 2018-07-04 Keith Hayton , Dimitrios Moirogiannis , Marcelo Magnasco

In this paper we develop a geometrical model of functional architecture for the processing of spatio-temporal visual stimuli. The model arises from the properties of the receptive field linear dynamics of orientation and speed-selective…

Analysis of PDEs · Mathematics 2013-05-06 Davide Barbieri , Giovanna Citti , Giacomo Cocci , Alessandro Sarti

We describe coordinate systems adapted for the space between two surfaces, such as those delineating the highly folded cortex in mammalian brains. These systems are estimated in order to satisfy geometric priors, including streamline…

Optimization and Control · Mathematics 2019-11-20 Laurent Younes , Kwame S. Kutten , J. Tilak Ratnanather

We investigate integral-geometric quantities arising from harmonic analysis which measure visibility and transversality. Motivated by their applications in multilinear Kakeya problems and affine-invariant measures on surfaces, we derive…

Functional Analysis · Mathematics 2025-11-25 Silouanos Brazitikos , Dimitris-Marios Liakopoulos

Effective analysis in neuroscience benefits significantly from robust conceptual frameworks. Traditional metrics of interbrain synchrony in social neuroscience typically depend on fixed, correlation-based approaches, restricting their…

Neurons and Cognition · Quantitative Biology 2025-12-01 Nicolás Hinrichs , Noah Guzmán , Melanie Weber

Effective learning of asymmetric and local features in images and other data observed on multi-dimensional grids is a challenging objective critical for a wide range of image processing applications involving biomedical and natural images.…

Methodology · Statistics 2022-10-06 Meng Li , Li Ma

Quantification of brain morphology has become an important cornerstone in understanding brain structure. Measures of cortical morphology such as thickness and surface area are frequently used to compare groups of subjects or characterise…

Neurons and Cognition · Quantitative Biology 2020-03-25 Yujiang Wang , Tobias Ludwig , Bethany Little , Joe H Necus , Gavin Winston , Sjoerd B Vos , Jane de Tisi , John S Duncan , Peter N Taylor , Bruno Mota

Despite their success, modern convolutional neural networks (CNNs) exhibit fundamental limitations, including data inefficiency, poor out-of-distribution generalization, and vulnerability to adversarial perturbations. These shortcomings can…

Neural and Evolutionary Computing · Computer Science 2025-11-25 Brennen A. Hill , Zhang Xinyu , Timothy Putra Prasetio

The traditional view of neural computation in the cerebral cortex holds that sensory neurons are specialized, i.e., selective for certain dimensions of sensory stimuli. This view was challenged by evidence of contextual interactions between…

Neurons and Cognition · Quantitative Biology 2022-04-26 Sergei Gepshtein , Ambarish Pawar , Sunwoo Kwon , Sergey Savel'ev , Thomas D. Albright

The study of neuronal morphology is important not only for its potential relationship with neuronal dynamics, but also as a means to classify diverse types of cells and compare than among species, organs, and conditions. In the present…

Neurons and Cognition · Quantitative Biology 2024-03-11 Alexandre Benatti , Henrique F. de Arruda , Luciano da F. Costa

This work investigates at what degree two neuromorphometric measurements, namely the autocorrelation and the excluded volume of a neuronal cell can influence the characterization and classification of such a type of cells. While the…

Statistical Mechanics · Physics 2007-05-23 L. da F. Costa , M. S. Barbosa , V. Coupez

Homology-based invariants can be used to characterize the geometry of datasets and thereby gain some understanding of the processes generating those datasets. In this work we investigate how the geometry of a dataset changes when it is…

Algebraic Topology · Mathematics 2022-03-17 Jens Agerberg , Wojciech Chacholski , Ryan Ramanujam

We propose a differential geometric model of hypercolumns in the primary visual cortex V1 that combines features of the symplectic model of the primary visual cortex by A. Sarti, G. Citti and J. Petitot and of the spherical model of…

Neurons and Cognition · Quantitative Biology 2024-10-29 D. V. Alekseevsky , A. Spiro

The success of deep neural networks in image classification and learning can be partly attributed to the features they extract from images. It is often speculated about the properties of a low-dimensional manifold that models extract and…

Computer Vision and Pattern Recognition · Computer Science 2022-05-04 Roozbeh Yousefzadeh

Recent work has established clear links between the generalization performance of trained neural networks and the geometry of their loss landscape near the local minima to which they converge. This suggests that qualitative and quantitative…

Machine Learning · Computer Science 2022-01-28 Stefan Horoi , Jessie Huang , Bastian Rieck , Guillaume Lajoie , Guy Wolf , Smita Krishnaswamy

Understanding geometry relies heavily on vision. In this work, we evaluate whether state-of-the-art vision language models (VLMs) can understand simple geometric concepts. We use a paradigm from cognitive science that isolates visual…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Eliza Kosoy , Annya Dahmani , Andrew K. Lampinen , Iulia M. Comsa , Soojin Jeong , Ishita Dasgupta , Kelsey Allen

In this paper, we present a novel method for analysis and segmentation of laminar structure of the cortex based on tissue characteristics whose change across the gray matter underlies distinctive between cortical layers. We develop and…

Computer Vision and Pattern Recognition · Computer Science 2019-12-16 Andrija Štajduhar , Tomislav Lipić , Goran Sedmak , Sven Lončarić , Miloš Judaš

We present a model, based on symmetry and geometry, for proteins. Using elementary ideas from mathematics and physics, we derive the geometries of discrete helices and sheets. We postulate a compatible solvent-mediated emergent pairwise…

Soft Condensed Matter · Physics 2023-06-21 Jayanth R. Banavar , Achille Giacometti , Trinh X. Hoang , Amos Maritan , Tatjana Škrbić

We consider some integral-geometric quantities that have recently arisen in harmonic analysis and elsewhere, derive some sharp geometric inequalities relating them, and place them in a wider context.

Functional Analysis · Mathematics 2024-04-09 Silouanos Brazitikos , Anthony Carbery , Finlay McIntyre

Segmentations are often necessary for the analysis of image data. They are used to identify different objects, for example cell nuclei, mitochondria, or complete cells in microscopic images. There might be features in the data, that cannot…

Computational Geometry · Computer Science 2016-05-31 Julia Portl , Heike Leitte