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Recurrent neural networks have gained widespread use in modeling sequence data across various domains. While many successful recurrent architectures employ a notion of gating, the exact mechanism that enables such remarkable performance is…

Machine Learning · Statistics 2018-08-16 Minmin Chen , Jeffrey Pennington , Samuel S. Schoenholz

Recent research demonstrate that prediction of time series by recurrent neural networks (RNNs) based on the noisy input generates a smooth anticipated trajectory. We examine the internal dynamics of RNNs and establish a set of conditions…

Machine Learning · Computer Science 2020-10-07 Boris Rubinstein

Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology as well as for the dissection of complex pathologic…

Molecular Networks · Quantitative Biology 2007-05-23 Kai Wang , Nilanjana Banerjee , Adam Margolin , Ilya Nemenman , Katia Basso , Riccardo Favera , Andrea Califano

Gene regulatory networks are collections of genes that interact with one other and with other substances in the cell. By measuring gene expression over time using high-throughput technologies, it may be possible to reverse engineer, or…

Applications · Statistics 2011-09-08 Andrea Rau , Florence Jaffrézic , Jean-Louis Foulley , R. W. Doerge

In a previous paper, we have shown that a recurrent neural network (RNN) can be used to detect cellular network radio signal degradations accurately. We unexpectedly found, though, that accuracy gains diminished as we added layers to the…

Machine Learning · Computer Science 2024-04-18 David Mulvey , Chuan Heng Foh , Muhammad Ali Imran , Rahim Tafazolli

We consider the task of discovering gene regulatory networks, which are defined as sets of genes and the corresponding transcription factors which regulate their expression levels. This can be viewed as a variable selection problem,…

Methodology · Statistics 2014-12-04 Justin Bleich , Adam Kapelner , Edward I. George , Shane T. Jensen

Bayesian Optimization algorithm has become a promising approach for nonlinear global optimization problems and many machine learning applications. Over the past few years, improvements and enhancements have been brought forward and they…

Machine Learning · Computer Science 2022-01-04 Yuyang Chen , Kaiming Bi , Chih-Hang J. Wu , David Ben-Arieh , Ashesh Sinha

Recurrent neural networks (RNNs) are well suited for solving sequence tasks in resource-constrained systems due to their expressivity and low computational requirements. However, there is still a need to bridge the gap between what RNNs are…

Machine Learning · Computer Science 2023-03-13 Anand Subramoney , Khaleelulla Khan Nazeer , Mark Schöne , Christian Mayr , David Kappel

We introduce a novel gene regulatory network (GRN) inference method that integrates optimal transport (OT) with a deep-learning structural inference model. Advances in next-generation sequencing enable detailed yet destructive gene…

Computational Engineering, Finance, and Science · Computer Science 2024-09-24 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

Regression neural networks (NNs) are most commonly trained by minimizing the mean squared prediction error, which is highly sensitive to outliers and data contamination. Existing robust training methods for regression NNs are often limited…

Machine Learning · Statistics 2026-02-10 Abhik Ghosh , Suryasis Jana

We propose a framework based on Recurrent Neural Networks (RNNs) to determine an optimal control strategy for a discrete-time system that is required to satisfy specifications given as Signal Temporal Logic (STL) formulae. RNNs can store…

Systems and Control · Electrical Eng. & Systems 2020-09-25 Wenliang Liu , Noushin Mehdipour , Calin Belta

In our earlier work, we introduced the concept of Gene Regulatory Neural Network (GRNN), which utilizes natural neural network-like structures inherent in biological cells to perform computing tasks using chemical inputs. We define this…

Neural and Evolutionary Computing · Computer Science 2024-03-14 Samitha Somathilaka , Adrian Ratwatte , Sasitharan Balasubramaniam , Mehmet Can Vuran , Witawas Srisa-an , Pietro Liò

Recurrent Neural Networks (RNNs) have been a prominent concept within artificial intelligence. They are inspired by Biological Neural Networks (BNNs) and provide an intuitive and abstract representation of how BNNs work. Derived from the…

Neural and Evolutionary Computing · Computer Science 2017-03-09 Stefano Nichele , Andreas Molund

With neural networks having demonstrated their versatility and benefits, the need for their optimal performance is as prevalent as ever. A defining characteristic, hyperparameters, can greatly affect its performance. Thus engineers go…

Neural and Evolutionary Computing · Computer Science 2020-09-21 Keshav Ganapathy

Neuro-evolution and neural architecture search algorithms have gained increasing interest due to the challenges involved in designing optimal artificial neural networks (ANNs). While these algorithms have been shown to possess the potential…

Neural and Evolutionary Computing · Computer Science 2019-10-01 Travis J. Desell , AbdElRahman A. ElSaid , Alexander G. Ororbia

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

Many neural networks exhibit stability in their activation patterns over time in response to inputs from sensors operating under real-world conditions. By capitalizing on this property of natural signals, we propose a Recurrent Neural…

Neural and Evolutionary Computing · Computer Science 2016-12-19 Daniel Neil , Jun Haeng Lee , Tobi Delbruck , Shih-Chii Liu

A formalism for describing the dynamics of Genetic Algorithms (GAs) using methods from statistical mechanics is applied to the problem of generalization in a perceptron with binary weights. The dynamics are solved for the case where a new…

Condensed Matter · Physics 2009-10-28 Magnus Rattray , Jonathan Shapiro

Probabilistic graphical models provide a powerful tool to describe complex statistical structure, with many real-world applications in science and engineering from controlling robotic arms to understanding neuronal computations. A major…

Artificial Intelligence · Computer Science 2023-05-04 Yicheng Fei , Xaq Pitkow

Several methods have been proposed to explain Deep Neural Network (DNN). However, to our knowledge, only classification networks have been studied to try to determine which input dimensions motivated the decision. Furthermore, as there is…

Computer Vision and Pattern Recognition · Computer Science 2020-04-16 Mégane Millan , Catherine Achard