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DNA supercoiling is central to many fundamental processes of living organisms. Its average level along the chromosome and over time reflects the dynamic equilibrium of opposite activities of topoisomerases, which are required to relax…

Biomolecules · Quantitative Biology 2023-10-09 Ivan Junier , Elham Ghobadpour , Olivier Espeli , Ralf Everaers

Simple expressions for the bending and the base-stacking energy of double-stranded semiflexible biopolymers (such as DNA and actin) are derived. The distribution of the folding angle between the two strands is obtained by solving a…

Soft Condensed Matter · Physics 2009-10-31 Zhou Haijun , Ou-Yang Zhong-can

Origami structures have been receiving a lot of attention from engineering and scientific researchers owing to their unique properties such as deployability, multi-stability, negative stiffness, etc. However, dynamic properties of origami…

Materials Science · Physics 2024-08-06 Sudheendra Herkal , Satish Nagarajaiah , Glaucio Paulino

We explore the surprisingly rich energy landscape of origami-like folding planar structures. We show that the configuration space of rigid-paneled degree-4 vertices, the simplest building blocks of such systems, consists of at least two…

Soft Condensed Matter · Physics 2017-09-26 Scott Waitukaitis , Rémi Menaut , Bryan Gin-ge Chen , Martin van Hecke

Deployable mechanical systems such as space solar panels rely on the intricate stowage of passive modules, and sophisticated deployment using a network of motorized actuators. As a result, a significant portion of the stowed mass and volume…

Applied Physics · Physics 2019-07-03 Tian Chen , Osama R. Bilal , Robert Lang , Chiara Daraio , Kristina Shea

In this study, we examine a rapid and reversible origami folding method by exploiting a combination of resonance excitation, asymmetric multi-stability, and active control. The underlying idea is that, by harmonically exciting a…

Applied Physics · Physics 2020-06-11 Sahand Sadeghi , Suyi Li

Polymer filaments form the foundation of biology from cell scaffolding to DNA. Their study and fabrication play an important role in a wide range of processes from tissue engineering to molecular machines. We present a simple method to…

Stiffness degradation and progressive failure of composite laminates are complex processes involving evolution and multi-mode interactions among fiber fractures, intra-ply matrix cracks and inter-ply delaminations. This paper presents a…

Numerical Analysis · Mathematics 2023-11-06 Jiakun Liu , Stuart Leigh Phoenix

The mechanical properties of DNA are typically described by elastic theories with purely local couplings (on-site models). We discuss and analyze coarse-grained (oxDNA) and all-atom simulations, which indicate that in DNA distal sites are…

Soft Condensed Matter · Physics 2021-04-21 Enrico Skoruppa , Aderik Voorspoels , Jocelyne Vreede , Enrico Carlon

Phase diagram of the ground states of DNA in a bad solvent is studied for a semi-flexible polymer model with a generalized local elastic bending potential characterized by a nonlinearity parameter $x$ and effective self-attraction promoting…

Biomolecules · Quantitative Biology 2016-01-28 Trinh X. Hoang , Hoa Lan Trinh , Achille Giacometti , Rudolf Podgornik , Jayanth R. Banavar , Amos Maritan

The mechanical model based on beads and springs, which we recently proposed to study non-specific DNA-protein interactions [J. Chem. Phys. 130, 015103 (2009)], was improved by describing proteins as sets of interconnected beads instead of…

Biological Physics · Physics 2009-10-29 Ana-Maria Florescu , Marc Joyeux

We study the ground-state entanglement of gapped domain walls between topologically ordered systems in two spatial dimensions. We derive a universal correction to the ground-state entanglement entropy, which is equal to the logarithm of the…

Strongly Correlated Electrons · Physics 2021-06-01 Bowen Shi , Isaac H. Kim

We predict the existence of a totally new class of phases in weakly coupled, three-dimensional stacks of two-dimensional (2D) XY-models. These ``sliding phases'' behave essentially like decoupled, independent 2D XY-models with precisely…

Soft Condensed Matter · Physics 2016-08-31 C. S. O'Hern , T. C. Lubensky , J. Toner

Branched junction molecule assembly of DNA nanostructures, pioneered by Seeman's laboratory in the 1980s, has become increasingly sophisticated, as have the assembly targets. A critical design step is finding minimal sets of branched…

Combinatorics · Mathematics 2021-08-03 Leyda Almodóvar , Jo Ellis-Monaghan , Amanda Harsy , Cory Johnson , Jessica Sorrells

Multistep denaturation in a short circular DNA molecule is analyzed by a mesoscopic Hamiltonian model which accounts for the helicoidal geometry. Computation of melting profiles by the path integral method suggests that stacking…

Soft Condensed Matter · Physics 2012-04-13 Marco Zoli

The mechanical properties of molecules are today captured by single molecule manipulation experiments, so that polymer features are tested at a nanometric scale. Yet devising mathematical models to get further insight beyond the commonly…

We present a dynamical model of DNA mechanical unzipping under the action of a force. The model includes the motion of the fork in the sequence-dependent landscape, the trap(s) acting on the bead(s), and the polymeric components of the…

Biomolecules · Quantitative Biology 2011-09-19 Carlo Barbieri , Simona Cocco , Remi Monasson , Francesco Zamponi

The folding transition of biopolymers from the coil to compact structures has attracted wide research interest in the past and is well studied in polymer physics. Recent seminal works on DNA in confined devices have shown that these long…

Soft Condensed Matter · Physics 2023-08-09 Keerthi Radhakrishnan , Sunil P. Singh

DNA bending is biologically important for genome regulation and is relevant to a range of nanotechnological systems. Recent results suggest that sharp bending is much easier than implied by the widely-used worm-like chain model; many of…

Biomolecules · Quantitative Biology 2015-07-01 Ryan M. Harrison , Flavio Romano , Thomas E. Ouldridge , Ard A. Louis , Jonathan P. K. Doye

We investigate the evolutionary dynamics of an idealised model for the robust self-assembly of two-dimensional structures called polyominoes. The model includes rules that encode interactions between sets of square tiles that drive the…

Populations and Evolution · Quantitative Biology 2013-09-03 Iain G. Johnston , Sebastian A. Ahnert , Jonathan P. K. Doye , Ard A. Louis