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In this paper, we consider the large-time behavior of solutions of a reaction diffusion system arising from a nuclear reactor model with the Robin boundary conditions, which consists of two real-valued unknown functions. In particular, we…

Analysis of PDEs · Mathematics 2018-11-12 Kosuke Kita , Mitsuharu Ôtani

Mass-action kinetics is frequently used in systems biology to model the behaviour of interacting chemical species. Many important dynamical properties are known to hold for such systems if they are weakly reversible and have a low…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

In this paper, we consider linear switched systems $\dot x(t)=A_{u(t)} x(t)$, $x\in\R^n$, $u\in U$, and the problem of asymptotic stability for arbitrary switching functions, uniform with respect to switching ({\bf UAS} for short). We first…

Optimization and Control · Mathematics 2007-05-23 Paolo Mason , Ugo Boscain , Yacine Chitour

Living systems operate out of equilibrium, continuously consuming energy to sustain organised, functional states. Their emergent behaviour usually relies on a set of interconnected chemical reaction networks (CRNs) driven by external fluxes…

Statistical Mechanics · Physics 2026-02-03 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

We consider the chemical reaction networks and study currents in these systems. Reviewing recent decomposition of rate functionals from large deviation theory for Markov processes, we adapt these results for reaction networks. In…

Mathematical Physics · Physics 2019-12-16 Johannes Zimmer , D. R. Michiel Renger

We propose a technique for the design and analysis of adaptation algorithms in dynamical systems. The technique applies both to systems with conventional Lyapunov-stable target dynamics and to ones of which the desired dynamics around the…

Optimization and Control · Mathematics 2007-05-23 Tyukin Ivan , Danil Prokhorov , Cees van Leeuwen

Reaction networks have been widely used as generic models in diverse areas of applied sciences, such as biology, chemistry, ecology, epidemiology, and computer science. A reaction network incorporating noisy effects is modeled as a…

Molecular Networks · Quantitative Biology 2026-05-12 Chuang Xu

We study path-complete Lyapunov functions, which are stability criteria for switched systems, described by a combinatorial component (namely, an automaton), and a functional component (a set of candidate Lyapunov functions, called the…

Optimization and Control · Mathematics 2022-09-20 Matteo Della Rossa , Raphaël M. Jungers

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics.

Dynamical Systems · Mathematics 2015-03-19 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

Chemical reaction networks (CRNs) model the behavior of chemical reactions in well-mixed solutions and they can be designed to perform computations. In this tutorial we give an overview of various computational models for CRNs. Moreover, we…

Emerging Technologies · Computer Science 2018-11-27 Robert Brijder

Chemically active mixtures exhibit complex patterns that emerge from the interplay of physical interactions and reactions among components. Individually, these two processes are well-understood: Physical interactions can give rise to phase…

Soft Condensed Matter · Physics 2026-04-30 Chengjie Luo , Yicheng Qiang , Guido L. A. Kusters , David Zwicker

The search for Lyapunov functions is a crucial task in the analysis of nonlinear systems. In this paper, we present a physics-informed neural network (PINN) approach to learning a Lyapunov function that is nearly maximal for a given stable…

Optimization and Control · Mathematics 2026-04-21 Jun Liu , Yiming Meng , Maxwell Fitzsimmons , Ruikun Zhou

In this paper, we focus on the problem about direct way to design a stable controller for nonlinear system. A framework of learning controller with Lyapunov-based constraint is proposed, which is intended to transform designing and analyis…

Systems and Control · Computer Science 2019-03-11 Me Le , Chi Yanxun , Li Zhiwei , Xu Dongfu , Zhang Yulong

This paper is concerned with programming adaptive linear neural networks (ALNNs) using chemical reaction networks (CRNs) equipped with mass-action kinetics. Through individually programming the forward propagation and the backpropagation of…

Dynamical Systems · Mathematics 2022-04-14 Yuzhen Fan , Xiaoyu Zhang , Chuanhou Gao

Lyapunov's second or direct method is one of the most widely used techniques for investigating stability properties of dynamical systems. This technique makes use of an auxiliary function, called a Lyapunov function, to ascertain stability…

Optimization and Control · Mathematics 2016-08-12 Christopher M. Kellett

We consider how to generate chemical reaction networks (CRNs) from functional specifications. We propose a two-stage approach that combines synthesis by satisfiability modulo theories and Markov chain Monte Carlo based optimisation. First,…

Emerging Technologies · Computer Science 2015-08-19 Neil Dalchau , Niall Murphy , Rasmus Petersen , Boyan Yordanov

We propose a learning-based method for Lyapunov stability analysis of piecewise affine dynamical systems in feedback with piecewise affine neural network controllers. The proposed method consists of an iterative interaction between a…

Optimization and Control · Mathematics 2020-11-24 Shaoru Chen , Mahyar Fazlyab , Manfred Morari , George J. Pappas , Victor M. Preciado

Stability margins for linear time-varying (LTV) and switched-linear systems are traditionally computed via quadratic Lyapunov functions, and these functions certify the stability of the system under study. In this work, we show how the more…

Systems and Control · Electrical Eng. & Systems 2020-12-08 Corbin Klett , Matthew Abate , Samuel Coogan , Eric Feron

Despite their spectacular progress, language models still struggle on complex reasoning tasks, such as advanced mathematics. We consider a long-standing open problem in mathematics: discovering a Lyapunov function that ensures the global…

Machine Learning · Computer Science 2024-10-14 Alberto Alfarano , François Charton , Amaury Hayat

Robustness of biochemical systems has become one of the central questions in systems biology although it is notoriously difficult to formally capture its multifaceted nature. Maintenance of normal system function depends not only on the…

Molecular Networks · Quantitative Biology 2012-03-28 Jost Neigenfind , Sergio Grimbs , Zoran Nikoloski
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