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Piecewise-Linear in Rates (PWLR) Lyapunov functions are introduced for a class of Chemical Reaction Networks (CRNs). In addition to their simple structure, these functions are robust with respect to arbitrary monotone reaction rates, of…

Optimization and Control · Mathematics 2016-09-09 M. Ali Al-Radhawi , David Angeli

We consider the relationship between stationary distributions for stochastic models of reaction systems and Lyapunov functions for their deterministic counterparts. Specifically, we derive the well known Lyapunov function of reaction…

Probability · Mathematics 2015-06-11 David F. Anderson , Gheorghe Craciun , Manoj Gopalkrishnan , Carsten Wiuf

We investigate a broad family of chemical reaction networks (CRNs) assigned with mass action kinetics, called complex-balanced-produced-CRNs (CBP-CRNs), which are generated by any given complex balanced mass action system (MAS) and whose…

Dynamical Systems · Mathematics 2019-11-12 Shan Wu , Yafei Lu , Chuanhou Gao

In this paper, we develop a method to generate the Lyapunov function for stability analysis for chemical reaction networks. Based on the Chemical Master Equation, we derive the Lyapunov Function partial differential equations (PDEs), whose…

Dynamical Systems · Mathematics 2020-10-01 Zhou Fang , Chuanhou Gao

Much of the theory on chemical-reaction networks (CRNs) has been developed in the ideal-solution limit, where interactions between the solutes are negligible. However, there is a large variety of phenomena in biological cells and…

Biological Physics · Physics 2022-12-09 Ander Movilla Miangolarra , Michele Castellana

In this paper the qualitative dynamical properties of so-called generalized ribosome flow models are studied. Ribosome flow models known from the literature are generalized by allowing an arbitrary directed network structure between the…

Dynamical Systems · Mathematics 2023-07-19 G. Szederkenyi , M. A. Vaghy

Quadratic Lyapunov functions are prevalent in stability analysis of linear consensus systems. In this paper we show that weighted sums of convex functions of the different coordinates are Lyapunov functions for irreducible consensus…

Optimization and Control · Mathematics 2015-01-08 Herbert Mangesius , Jean-Charles Delvenne

In 1961, R\'enyi discovered a rich family of non-classical Lyapunov functions for kinetics of the Markov chains, or, what is the same, for the linear kinetic equations. This family was parameterised by convex functions on the positive…

Chemical Physics · Physics 2019-07-24 A. N. Gorban

In this paper, we propose a novel technique, referred to as the Lyapunov Function PDEs technique, to diagnose persistence of chemical reaction networks with mass-action kinetics. The technique allows that every network is attached to a…

Dynamical Systems · Mathematics 2019-02-01 Xiaoyu Zhang , Zhou Fang , Chuanhou Gao

This work studies the problem of searching for homogeneous polynomial Lyapunov functions for stable switched linear systems. Specifically, we show an equivalence between polynomial Lyapunov functions for systems of this class and quadratic…

Systems and Control · Electrical Eng. & Systems 2020-02-20 Matthew Abate , Corbin Klett , Samuel Coogan , Eric Feron

Motivation: A Chemical Reaction Network (CRN) is a set of chemical reactions, which can be very complex and difficult to analyze. Indeed, dynamical properties of CRNs can be described by a set of non-linear differential equations that…

Computational Engineering, Finance, and Science · Computer Science 2021-07-02 Lucia Nasti , Roberta Gori , Paolo Milazzo , Federico Poloni

This paper studies the use of vector Lyapunov functions for the design of globally stabilizing feedback laws for nonlinear systems. Recent results on vector Lyapunov functions are utilized. The main result of the paper shows that the…

Optimization and Control · Mathematics 2012-01-13 Iasson Karafyllis , Zhong-Ping Jiang

We consider delayed chemical reaction networks with generalized kinetics of product form and show that complex balancing implies that within each positive stoichiometric compatibility class there is a unique positive equilibrium that is…

Dynamical Systems · Mathematics 2024-07-15 Mihály András Vághy , Gábor Szederkényi

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated…

Dynamical Systems · Mathematics 2013-04-11 Pete Donnell , Murad Banaji

This paper considers a wide class of smooth continuous dynamic nonlinear systems (control objects) with a measurable vector of state. The problem is to find a special function (Lyapunov function), which in the framework of the second…

Systems and Control · Electrical Eng. & Systems 2023-07-07 A. M. Zenkin , A. A. Peregudin , A. A. Bobtsov

In this work we addressed the problem of stability analysis for an uncertain piecewise affine model of a genetic regulatory network. In particular we considered polytopic parameter uncertainties on the proteins production rate functions,…

Systems and Control · Electrical Eng. & Systems 2019-07-01 Mirko Pasquini , David Angeli

The study of the dynamics of chemical reactions, and in particular phenomena such as oscillating reactions, has led to the recognition that many dynamical properties of a chemical reaction can be predicted from graph theoretical properties…

Dynamical Systems · Mathematics 2022-11-08 J. J. P. Veerman , Tessa Whalen-Wagner , Ewan Kummel

A numerically effective procedure for determining weakly reversible chemical reaction networks that are linearly conjugate to a known reaction network is proposed in this paper. The method is based on translating the structural and…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Recently, A.N. Gorban presented a rich family of universal Lyapunov functions for any linear or non-linear reaction network with detailed or complex balance. Two main elements of the construction algorithm are partial equilibria of…

Chemical Physics · Physics 2020-04-30 Evgeny M Mirkes

We propose a unified framework that allows for the full mechanistic reconstruction of chemical reaction networks (CRNs) from concentration data. The framework utilizes an integral formulation of the differential equations governing the…

Numerical Analysis · Mathematics 2026-02-13 Abraham Reyes-Velazquez , Stefan Güttel , Igor Larrosa , Jonas Latz
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