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Related papers: Robust Lyapunov Functions for Reaction Networks: A…

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Chemical Reaction Neural Networks (CRNNs) have emerged as an interpretable machine learning framework for discovering reaction kinetics directly from data, while strictly adhering to the Arrhenius and mass action laws. However, standard…

Chemical Physics · Physics 2026-05-15 Benjamin C. Koenig , Sili Deng

The use of mathematical models has helped to shed light on countless phenomena in chemistry and biology. Often, though, one finds that systems of interest in these fields are dauntingly complex. In this paper, we attempt to synthesize and…

Molecular Networks · Quantitative Biology 2007-09-04 Mark Lipson

Across many disciplines, chemical reaction networks (CRNs) are an established population model defined as a system of coupled nonlinear ordinary differential equations. In many applications, for example, in systems biology and epidemiology,…

Systems and Control · Electrical Eng. & Systems 2023-01-23 Kim G. Larsen , Daniele Toller , Mirco Tribastone , Max Tschaikowski , Andrea Vandin

Formal methods have enabled breakthroughs in many fields, such as in hardware verification, machine learning and biological systems. The key object of interest in systems biology, synthetic biology, and molecular programming is chemical…

Emerging Technologies · Computer Science 2020-08-11 Marko Vasic , David Soloveichik , Sarfraz Khurshid

This is an expository note on large deviations, Hamilton-Jacobi-Bellman (HJB) equations, and the role of the Freidlin-Wentzell quasipotential in Chemical Reaction Networks (CRNs). The note was motivated by observations which identified…

Probability · Mathematics 2021-08-12 Michael Snarski

Inspired by the widespread concept of Lyapunov-Krasovskii functionals of complete type, this article proposes an alternative class of functionals, termed Lyapunov-Krasovskii functionals of robust type. Their construction aims at improving…

Systems and Control · Electrical Eng. & Systems 2025-11-12 Tessina H. Scholl

This paper presents adaptive robust quadratic program (QP) based control using control Lyapunov and barrier functions for nonlinear systems subject to time-varying and state-dependent uncertainties. An adaptive estimation law is proposed to…

Optimization and Control · Mathematics 2020-10-21 Pan Zhao , Yanbing Mao , Chuyuan Tao , Naira Hovakimyan , Xiaofeng Wang

We propose a novel framework for the Lyapunov analysis of an important class of hybrid systems, inspired by the theory of symbolic dynamics and earlier results on the restricted class of switched systems. This new framework allows us to…

Optimization and Control · Mathematics 2024-07-24 Matteo Della Rossa , Raphaël M. Jungers

We construct an explicit Lyapunov function for scalar parabolic reaction-advection-diffusion equations under periodic boundary conditions. We assume the nonlinearity is even in the advection term. We follow a method originally suggested by…

Dynamical Systems · Mathematics 2018-02-28 Bernold Fiedler , Clodoaldo Grotta-Ragazzo , Carlos Rocha

Robust stabilization conditions for uncertain switched affine systems subject to a unitary input delay are presented. They are obtained through the Lyapunov framework and a min-switching state-feedback predictive control law. The result…

Systems and Control · Electrical Eng. & Systems 2026-04-20 Gerson Portilla , Carolina Albea , Alexandre Seuret

Graph Neural Networks (GNNs) are highly vulnerable to adversarial perturbations in both topology and features, making the learning of robust representations a critical challenge. In this work, we bridge GNNs with control theory to introduce…

Machine Learning · Computer Science 2026-03-16 Haoyu Chu , Xiaotong Chen , Wei Zhou , Wenjun Cui , Kai Zhao , Shikui Wei , Qiyu Kang

Chemical reaction networks (CRN) comprise an important class of models to understand biological functions such as cellular information processing, the robustness and control of metabolic pathways, circadian rhythms, and many more. However,…

Molecular Networks · Quantitative Biology 2025-03-25 Dimitri Loutchko , Yuki Sughiyama , Tetsuya J. Kobayashi

We propose new methods for learning control policies and neural network Lyapunov functions for nonlinear control problems, with provable guarantee of stability. The framework consists of a learner that attempts to find the control and…

Machine Learning · Computer Science 2022-09-26 Ya-Chien Chang , Nima Roohi , Sicun Gao

In this paper, we propose a Lyapunov-based reinforcement learning method for distributed control of nonlinear systems comprising interacting subsystems with guaranteed closed-loop stability. Specifically, we conduct a detailed stability…

Systems and Control · Electrical Eng. & Systems 2024-12-17 Jingshi Yao , Minghao Han , Xunyuan Yin

We study optimization-based criteria for the stability of switching systems, known as Path-Complete Lyapunov Functions, and ask the question "can we decide algorithmically when a criterion is less conservative than another". Our…

Dynamical Systems · Mathematics 2017-12-04 Matthew Philippe , Nikolaos Athanasopoulos , David Angeli , Raphaël M. Jungers

This paper considers the problem of characterizing the stability region of a large-scale networked system comprised of dissipative nonlinear subsystems, in a distributed and computationally tractable way. One standard approach to estimate…

Systems and Control · Electrical Eng. & Systems 2022-07-19 Amit Jena , Tong Huang , S. Sivaranjani , Dileep Kalathil , Le Xie

This paper provides a first example of constructing Lyapunov functions in a class of piecewise linear systems with limit cycles. The method of construction helps analyze and control complex oscillating systems through novel geometric means.…

Chaotic Dynamics · Physics 2013-07-01 Yian Ma , Ruoshi Yuan , Yang Li , Ping Ao , Bo Yuan

Chemical reaction networks (CRNs) are prototypical complex systems because reactions are nonlinear and connected in intricate ways, and they are also essential to understand living systems. Here, I discuss how recent developments in…

Statistical Mechanics · Physics 2020-12-23 Massimiliano Esposito

The network structure (or topology) of a dynamical network is often unavailable or uncertain. Hence, we consider the problem of network reconstruction. Network reconstruction aims at inferring the topology of a dynamical network using…

Optimization and Control · Mathematics 2018-09-26 Henk J. van Waarde , Pietro Tesi , M. Kanat Camlibel

The topic of this manuscript is the stability analysis of continuous-time switched nonlinear systems with constraints on the admissible switching signals. Our particular focus lies in considering signals characterized by upper and lower…

Optimization and Control · Mathematics 2024-01-17 Matteo Della Rossa