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Network-based intervention strategies can be effective and cost-efficient approaches to curtailing harmful contagions in myriad settings. As studied, these strategies are often impractical to implement, as they typically assume complete…

Physics and Society · Physics 2020-09-09 Samuel F. Rosenblatt , Jeffrey A. Smith , G. Robin Gauthier , Laurent Hébert-Dufresne

Malware attacks in today's vast digital ecosystem pose a serious threat. Understanding malware propagation dynamics and designing effective control strategies are therefore essential. In this work, we propose a generic SEIRV model…

Cryptography and Security · Computer Science 2026-03-05 Samiran Ghosh , V Anil Kumar

We review research papers which use game theory to model the decision making of individuals during an epidemic, attempting to classify the literature and identify the emerging trends in this field. We show that the literature can be…

Populations and Evolution · Quantitative Biology 2020-02-13 Sheryl L. Chang , Mahendra Piraveenan , Philippa Pattison , Mikhail Prokopenko

Statistical analysis based on quantile regression methods is more comprehensive, flexible, and less sensitive to outliers when compared to mean regression methods. When the link between different diseases are of interest, joint disease…

Methodology · Statistics 2022-02-01 Hanan Alahmadi , Håvard Rue , Janet van Niekerk

Determining the distribution of disease prevalence among heterogeneous populations at the national scale is fundamental for epidemiology and public health. Here, we use a combination of methods (spatial scan statistic, topological data…

Populations and Evolution · Quantitative Biology 2018-11-21 Alejandro Feged-Rivadeneira , Andrés Angel , Felipe González-Casabianca , Camilo Rivera

Recent shifts in global health priorities have positioned Population Health Management (PHM) as a central area of focus. However, optimizing PHM strategies presents several challenges: managing high-dimensional patient covariates, tracking…

Optimization and Control · Mathematics 2026-04-10 Daniel Adelman , Alba V Olivares-Nadal , Miaolan Xie

The state of the art of epidemic modelling in terrestrial ecosystems is the compartmental SIR model and its extensions from the now classical work of Kermack-Mackendrick. In contrast, epidemic modelling of marine ecosystems is a bit behind,…

Populations and Evolution · Quantitative Biology 2021-12-15 Àlex Giménez-Romero , Amalia Grau , Iris E. Hendriks , Manuel A. Matias

Malaria constitutes an important cause of human mortality. After 2009 Greece experienced a resurgence of malaria. Here, we develop a modelbased framework that integrates entomological, geographical, social and environmental evidence in…

In this paper, we study the optimal control for an SEIR model adapted to the vaccination strategy of susceptible individuals. There are factors associated with a vaccination campaign that make this strategy not only a public health issue…

Optimization and Control · Mathematics 2024-11-08 Nelson L. Santos Junior , João A. M. Gondim

We focus on the problem of uncertainty informed allocation of medical resources (vaccines) to heterogeneous populations for managing epidemic spread. We tackle two related questions: (1) For a compartmental ordinary differential equation…

Optimization and Control · Mathematics 2023-07-04 Samarth Gupta , Saurabh Amin

Epidemiological models for the spread of pathogens in a population are usually only able to describe a single pathogen. This makes their application unrealistic in cases where multiple pathogens with similar symptoms are spreading…

Social and Information Networks · Computer Science 2018-05-16 Nir Levy , Michael Iv , Elad Yom-Tov

We present a deterministic mathematical model for malaria transmission with waning immunity. The model consists of five non-linear system of differential equations. We used next generation matrix to derive the basic reproduction number…

Populations and Evolution · Quantitative Biology 2017-07-07 Miliyon Tilahun

This paper proposes a new formulation for the dynamic resource allocation problem, which converts the traditional MDP model with known parameters and no capacity constraints to a new model with uncertain parameters and a resource capacity…

Optimization and Control · Mathematics 2020-11-10 Onur Demiray , Evrim Didem Güneş , Lerzan Örmeci

We investigate a model for a mosquito-borne epidemic in which human hosts may adopt protective behaviour against vector bites in response to information on both past and current disease prevalence. Assuming that mosquitoes can also feed on…

Populations and Evolution · Quantitative Biology 2026-05-08 Simone De Reggi , Andrea Pugliese , Mattia Sensi , Cinzia Soresina

Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites,…

Populations and Evolution · Quantitative Biology 2021-07-05 Somya Mehra , Eva Stadler , David Khoury , James M. McCaw , Jennifer A. Flegg

This study develops and analyzes an extended Susceptible, Infected, Hospitalized and Recovered (SIHR) model incorporating time dependent control functions to capture preventive measures (e.g., distancing, mask use) and resource limited…

Populations and Evolution · Quantitative Biology 2025-10-01 Liban Ismail , Yahyeh Souleiman , Saraless Nadarajah , Abdisalam Hassan

This paper considers the problem of designing non-pharmaceutical intervention (NPI) strategies, such as masking and social distancing, to slow the spread of a viral epidemic. We formulate the problem of jointly minimizing the infection…

Systems and Control · Electrical Eng. & Systems 2024-12-02 Shiyu Cheng , Luyao Niu , Bhaskar Ramasubramanian , Andrew Clark , Radha Poovendran

In face of climate change and increasing urbanization, the predictive mosquito-borne diseases (MBD) transmission models require constant updates. Thus, is urgent to comprehend the driving forces of this non stationary behavior, observed…

Quantitative Methods · Quantitative Biology 2024-11-22 Marcio Maciel Bastos , Luiz Max Carvalho , Eduardo Correa Araujo , Flávio Codeço Coelho

Timely and effective decision-making is critical during epidemics to reduce preventable infections and deaths. This demands integrated models that jointly capture disease dynamics, vaccine distribution, regional disparities, and behavioral…

Social and Information Networks · Computer Science 2025-11-26 Kimiya Jozani , Nihal A. Sageer , Hode Eldardiry , Sait Tunc , Esra Buyuktahtakin Toy

Existing strategies for determining the optimal treatment or monitoring strategy typically assume unlimited access to resources. However, when a health system has resource constraints, such as limited funds, access to medication, or…

Applications · Statistics 2019-03-18 Ellen C Caniglia , Eleanor J Murray , Miguel A Hernan , Zach Shahn