Related papers: Multi-year optimization of malaria intervention: a…
Extrinsic environmental factors influence the distribution and population dynamics of many organisms, including insects that are of concern for human health and agriculture. This is particularly true for vector-borne infectious diseases,…
In this article, we consider a simplified model of time dynamics for a mosquito population subject to the artificial introduction of {\itshape Wolbachia}-infected mosquitoes, in order to fight arboviruses transmission.Indeed, it has been…
We study a resource allocation problem for containing an infectious disease in a metapopulation subject to resource uncertainty. We propose a two-stage model where the policy maker seeks to allocate resources in both stages where the second…
In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…
We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…
Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but they impose considerable societal, individual, and economic costs. We developed a general optimization framework to…
We study the impact of parameter estimation and state measurement errors on a control framework for optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic…
Malaria is a parasitic disease that is a major health problem in many tropical regions. The most characteristic symptom of malaria is fever. The fraction of fevers that are attributable to malaria, the malaria attributable fever fraction…
Characterizing the shared memberships of individuals in a classification scheme poses severe interpretability issues, even when using a moderate number of classes (say 4). Mixed membership models quantify this phenomenon, but they typically…
More than half of the world's population is exposed to the risk of mosquito-borne diseases, which leads to millions of cases and hundreds of thousands of deaths every year. Analyzing this type of data is often complex and poses several…
Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…
According to the World Malaria Report of 2022, 247 million cases of malaria and 619,000 related deaths were reported in 2021. This highlights the predominance of the disease, especially in the tropical and sub-tropical regions of Africa,…
Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…
We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. Applying the Pontryagin's…
We consider the problem of controlling an SIR-model epidemic by temporarily reducing the rate of contact within a population. The control takes the form of a multiplicative reduction in the contact rate of infectious individuals. The…
This paper studies the problem of optimally allocating treatments in the presence of spillover effects, using information from a (quasi-)experiment. I introduce a method that maximizes the sample analog of average social welfare when…
Vaccines have proven effective in mitigating the threat of severe infections and deaths during outbreaks of infectious diseases. However, vaccine hesitancy (VH) complicates disease spread prediction and healthcare resource assessment across…
We consider an SLIARS mathematical epidemiology model including intervention in the form of vaccination and treatment. Contrary to classical models, it is assumed that treatment doses can be limited in availability. Mathematically, we show…
This paper investigates the deterministic extinction and permanence of a family of SEIRS malaria models with multiple random delays, and with a general nonlinear incidence rate. The conditions for the extinction and permanence of the…
Sequential decision-making under cost-sensitive tasks is prohibitively daunting, especially for the problem that has a significant impact on people's daily lives, such as malaria control, treatment recommendation. The main challenge faced…