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Background: MR-based subchondral bone effectively predicts knee osteoarthritis. However, its clinical application is limited by the cost and time of MR. Purpose: We aim to develop a novel distillation-learning-based method named SRRD for…

Image and Video Processing · Electrical Eng. & Systems 2023-07-12 Yuqi Hu , Xiangyu Zhao , Gaowei Qing , Kai Xie , Chenglei Liu , Lichi Zhang

In this study, we evaluate the performance of three algorithms as computational models of trabecular bone architecture, through systematic evaluation of morphometric, topological, and mechanical properties. Here, we consider the widely-used…

Medical Physics · Physics 2022-11-24 Mahtab Vafaeefar , Kevin M. Moerman , Majid Kavousi , Ted J. Vaughan

Automatic and precise multi-class vertebrae segmentation from CT images is crucial for various clinical applications. However, due to similar appearances between adjacent vertebrae and the existence of various pathologies, existing…

Image and Video Processing · Electrical Eng. & Systems 2025-05-29 Xin You , Yixin Lou , Minghui Zhang , Jie Yang , Yun Gu

We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for…

Tissues and Organs · Quantitative Biology 2017-11-21 S. Aland , F. Stenger , R. Müller , M. Kampschulte , A. C. Langheinrich , T. El Khassawna , C. Heiß , A. Dreutsch , A. Voigt

Cervical spine fractures demand rapid and accurate diagnosis for effective clinical management. This study presents an automated, end-to-end pipeline for fracture detection across cervical vertebrae (C1--C7) that assesses the feasibility of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Fabi Nahian Madhurja , Rusab Sarmun , Muhammad E. H. Chowdhury , Adam Mushtak , Israa Al-Hashimi , Sohaib Bassam Zoghoul

The aim of this paper is to develop a multiscale hierarchical hybrid model based on finite element analysis and neural network computation to link mesoscopic scale (trabecular network level) and macroscopic (whole bone level) to simulate…

Medical Physics · Physics 2011-07-20 Ridha Hambli , Abdelwahed Barkaoui

Neuroimaging measures of the brain's white matter connections can enable the prediction of non-imaging phenotypes, such as demographic and cognitive measures. Existing works have investigated traditional microstructure and connectivity…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Wan Liu , Yuqian Chen , Chuyang Ye , Nikos Makris , Yogesh Rathi , Weidong Cai , Fan Zhang , Lauren J. O'Donnell

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

Whether comparing networks to each other or to random expectation, measuring dissimilarity is essential to understanding the complex phenomena under study. However, determining the structural dissimilarity between networks is an ill-defined…

Social and Information Networks · Computer Science 2018-07-26 Leo Torres , Pablo Suarez-Serrato , Tina Eliassi-Rad

Motivated by the challenging segmentation task of pancreatic tubular networks, this paper tackles two commonly encountered problems in biomedical imaging: Topological consistency of the segmentation, and expensive or difficult annotation.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Kasra Arnavaz , Oswin Krause , Kilian Zepf , Jelena M. Krivokapic , Silja Heilmann , Jakob Andreas Bærentzen , Pia Nyeng , Aasa Feragen

Plain radiography is the most common modality to assess the stage of osteoarthritis. Our aims were to assess the relationship of radiography-based bone density and texture between radiographs with minimal and clinical post-processing, and…

Medical Physics · Physics 2019-02-07 Jukka Hirvasniemi , Jaakko Niinimäki , Jérôme Thevenot , Simo Saarakkala

Diffusion MRI (dMRI) streamline tractography, the gold standard for in vivo estimation of brain white matter (WM) pathways, has long been considered indicative of macroscopic relationships with WM microstructure. However, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Tian Yu , Yunhe Li , Michael E. Kim , Chenyu Gao , Qi Yang , Leon Y. Cai , Susane M. Resnick , Lori L. Beason-Held , Daniel C. Moyer , Kurt G. Schilling , Bennett A. Landman

Tractography algorithms are used extensively to delineate white matter structures, by operating on the voxel-wise information generated through the application of diffusion tensor imaging (DTI) or other models to diffusion weighted (DW)…

Quantitative Methods · Quantitative Biology 2024-03-05 Richard G. Carson , Alexander Leemans

There are several metrics (Modularity, Mutual Information, Conductance, etc.) to evaluate the strength of graph clustering in large graphs. These metrics have great significance to measure the effectiveness and they are often used to find…

Social and Information Networks · Computer Science 2016-10-12 Md. Khaledur Rahman

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

In this paper, we present a deep-learning based method for estimating the 3D structure of a bone from a pair of 2D X-ray images. Our triplet loss-trained neural network selects the most closely matching 3D bone shape from a predefined set…

Computer Vision and Pattern Recognition · Computer Science 2020-10-12 Jana Čavojská , Julian Petrasch , Nicolas J. Lehmann , Agnès Voisard , Peter Böttcher

While many approaches to make neural networks more fathomable have been proposed, they are restricted to interrogating the network with input data. Measures for characterizing and monitoring structural properties, however, have not been…

Machine Learning · Computer Science 2019-09-30 Bastian Rieck , Matteo Togninalli , Christian Bock , Michael Moor , Max Horn , Thomas Gumbsch , Karsten Borgwardt

Cardiac deformation is a crucial biomarker for the evaluation of cardiac function. Current methods for estimating cardiac strain might underestimate local deformation due to through-plane motion and segmental averaging. Mesh-based mapping…

Tissues and Organs · Quantitative Biology 2025-04-07 Beatrice Moscoloni , Patrick Segers , Mathias Peirlinck

High energy impacts at joint locations often generate highly fragmented, or comminuted, bone fractures. Current approaches for treatment require physicians to decide how to classify the fracture within a hierarchy fracture severity…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Pengcheng Liu , Nathan Hewitt , Waseem Shadid , Andrew Willis

The present research aims to provide a practical numerical tool for the mechanical analysis of nanoscale trusses with similar accuracy to molecular dynamics (MD). As a first step, MD simulations of uniaxial tensile and compression tests of…

Applied Physics · Physics 2023-11-29 Marko Čanađija , Valentina Košmerl , Martin Zlatić , Domagoj Vrtovšnik , Neven Munjas