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Lifelong learning and adaptability are two defining aspects of biological agents. Modern reinforcement learning (RL) approaches have shown significant progress in solving complex tasks, however once training is concluded, the found…

Neural and Evolutionary Computing · Computer Science 2022-04-20 Elias Najarro , Sebastian Risi

This work carries out a detailed transient analysis of the learning behavior of multi-agent networks, and reveals interesting results about the learning abilities of distributed strategies. Among other results, the analysis reveals how…

Multiagent Systems · Computer Science 2015-04-21 Jianshu Chen , Ali H. Sayed

During mammalian development the cerebral metabolic rate correlates qualitatively with synaptogenesis, and both often exhibit bimodal temporal profiles. Despite these non-monotonic dependencies, it is found based on empirical data for…

Neurons and Cognition · Quantitative Biology 2012-04-19 Jan Karbowski

Often the development of novel functional peptides is not amenable to high throughput or purely computational screening methods. Peptides must be synthesized one at a time in a process that does not generate large amounts of data. One way…

Biomolecules · Quantitative Biology 2020-12-14 Rainier Barrett , Andrew D. White

We consider the problem of reinforcement learning when provided with (1) a baseline control policy and (2) a set of constraints that the learner must satisfy. The baseline policy can arise from demonstration data or a teacher agent and may…

Machine Learning · Computer Science 2021-07-13 Tsung-Yen Yang , Justinian Rosca , Karthik Narasimhan , Peter J. Ramadge

Synapses are information efficient in the sense that their natural conductance values convey as many bits per Joule as possible, but efficiency falls rapidly if the conductance is forced to deviate from its natural value (Harris et al,…

Neurons and Cognition · Quantitative Biology 2026-05-19 James V Stone

A common view on the brain learning processes proposes that the three classic learning paradigms -- unsupervised, reinforcement, and supervised -- take place in respectively the cortex, the basal-ganglia, and the cerebellum. However,…

Neurons and Cognition · Quantitative Biology 2021-06-08 Giovanni Granato , Emilio Cartoni , Federico Da Rold , Andrea Mattera , Gianluca Baldassarre

Normalization is a critical operation in neural circuits. In the brain, there is evidence that normalization is implemented via inhibitory interneurons and allows neural populations to adjust to changes in the distribution of their inputs.…

Neurons and Cognition · Quantitative Biology 2026-03-19 Roy Henha Eyono , Daniel Levenstein , Arna Ghosh , Jonathan Cornford , Blake Richards

From the point of view of the human brain, continual learning can perform various tasks without mutual interference. An effective way to reduce mutual interference can be found in sparsity and selectivity of neurons. According to Aljundi et…

Machine Learning · Computer Science 2024-10-04 Jin Hyun Park

Many computer vision applications require solving multiple tasks in real-time. A neural network can be trained to solve multiple tasks simultaneously using multi-task learning. This can save computation at inference time as only a single…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Trevor Standley , Amir R. Zamir , Dawn Chen , Leonidas Guibas , Jitendra Malik , Silvio Savarese

Stimulus from the environment that guides behavior and informs decisions is encoded in the firing rates of neural populations. Each neuron in the populations, however, does not spike independently: spike events are correlated from cell to…

Neurons and Cognition · Quantitative Biology 2012-07-24 Nicholas Cain , Eric Shea-Brown

We initiate a line of investigation into biological neural networks from an algorithmic perspective. We develop a simplified but biologically plausible model for distributed computation in stochastic spiking neural networks and study…

Neural and Evolutionary Computing · Computer Science 2016-10-10 Nancy Lynch , Cameron Musco , Merav Parter

Humans and other animals are capable of improving their learning performance as they solve related tasks from a given problem domain, to the point of being able to learn from extremely limited data. While synaptic plasticity is generically…

Machine Learning · Computer Science 2022-10-04 Nicolas Zucchet , Simon Schug , Johannes von Oswald , Dominic Zhao , João Sacramento

Human learning relies on specialization -- distinct cognitive mechanisms working together to enable rapid learning. In contrast, most modern neural networks rely on a single mechanism: gradient descent over an objective function. This…

Machine Learning · Computer Science 2025-05-16 Daniel Weitekamp , Christopher MacLellan , Erik Harpstead , Kenneth Koedinger

The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…

Machine Learning · Computer Science 2024-09-27 Jacobo Ruiz , Manas Gupta

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

In this work we revisit the most fundamental building block in deep learning, the multi-layer perceptron (MLP), and study the limits of its performance on vision tasks. Empirical insights into MLPs are important for multiple reasons. (1)…

Machine Learning · Computer Science 2023-10-04 Gregor Bachmann , Sotiris Anagnostidis , Thomas Hofmann

Working memory requires the brain to maintain information from the recent past to guide ongoing behavior. Neurons can contribute to this capacity by slowly integrating their inputs over time, creating persistent activity that outlasts the…

Neurons and Cognition · Quantitative Biology 2025-11-20 Nicoas Zucchet , Qianqian Feng , Axel Laborieux , Friedemann Zenke , Walter Senn , João Sacramento

Recent experimental studies indicate that synaptic changes induced by neuronal activity are discrete jumps between a small number of stable states. Learning in systems with discrete synapses is known to be a computationally hard problem.…

Neurons and Cognition · Quantitative Biology 2009-11-13 Carlo Baldassi , Alfredo Braunstein , Nicolas Brunel , Riccardo Zecchina

Competitive dynamics are thought to occur in many processes of learning involving synaptic plasticity. Here we show, in a game theory-inspired model of synaptic interactions, that the competition between synapses in their weak and strong…

Disordered Systems and Neural Networks · Physics 2015-05-28 Gaurang Mahajan , Anita Mehta