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Related papers: Ribosome Flow Model on a Ring

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We introduce and analyze two general dynamical models for unidirectional movement of particles along a circular chain and an open chain of sites. The models include a soft version of the simple exclusion principle, that is, as the density…

Quantitative Methods · Quantitative Biology 2019-03-14 Eyal Bar-Shalom , Alexander Ovseevich , Michael Margaliot

We theoretically study the Totally Asymmetric Exclusion Process (TASEP) with quenched jumping rates disorder and finite lifetime chain. TASEP is widely used to model the translation of messenger RNAs by Ribosomes in protein synthesis. Since…

Fundamental biological processes such as transcription and translation, where a genetic sequence is sequentially read by a macromolecule, have been well described by a classical model of non-equilibrium statistical physics, the totally…

Quantitative Methods · Quantitative Biology 2019-08-15 Jingkui Wang , Benjamin Pfeuty , Quentin Thommen , Carmen Romano , Marc Lefranc

We consider the one-dimensional totally asymmetric simple exclusion process (TASEP) with position-dependent hopping rates. The problem is solved,in a mean field/adiabatic approximation, for a general (smooth) form of spatial rate variation.…

Statistical Mechanics · Physics 2011-06-15 R. B. Stinchcombe , S. L. A. de Queiroz

The Ribosome Flow Model (RFM) describes the unidirectional movement of interacting particles along a one-dimensional chain of sites. As a site becomes fuller, the effective entry rate into this site decreases. The RFM has been used to model…

Networking and Internet Architecture · Computer Science 2015-08-26 Yoram Zarai , Oz Mendel , Michael Margaliot

The totally asymmetric simple exclusion process (TASEP) is a basic model of statistical mechanics that has found numerous applications. We consider the case of TASEP with a finite chain where particles may enter from the left and leave to…

Dynamical Systems · Mathematics 2020-06-23 Lars Grüne , Thomas Kriecherbauer , Michael Margaliot

We explore and quantify the physical and biochemical mechanisms that may be relevant in the regulation of translation. After elongation and detachment from the 3' termination site of mRNA, parts of the ribosome machinery can diffuse back to…

Soft Condensed Matter · Physics 2009-11-10 Tom Chou

mRNA translation is a crucial process that leads to protein synthesis in living cells. Therefore, it is a process that needs to work optimally for a cell to stay healthy and alive. With advancements in microscopy and novel experimental…

Subcellular Processes · Quantitative Biology 2023-12-20 Binil Shyam T , Rati Sharma

A discrete asymmetric exclusion process (ASEP) is developed to model proton conduction along one-dimensional water wires. Each lattice site represents a water molecule that can be in only one of three states; protonated, left-pointing, and…

Statistical Mechanics · Physics 2009-11-07 Tom Chou

We investigate a balance network of the asymmetric simple exclusion process (ASEP). Subsystems consisting of ASEPs are connected by bidirectional links with each other, which results in balance between every pair of subsystems. The network…

Statistical Mechanics · Physics 2013-02-18 Takahiro Ezaki , Katsuhiro Nishinari

The ribosome flow model (RFM) is a phenomenological model for the unidirectional flow of particles along a 1D chain of $n$ sites. The RFM has been extensively used to study the dynamics of ribosome flow along a single mRNA molecule during…

Molecular Networks · Quantitative Biology 2026-01-09 Aliza Ehrman , Thomas Kriecherbauer , Lars Gruene , Michael Margaliot

We introduce a model of a totally asymmetric simple exclusion process (TASEP) on a tree network where the aggregate hopping rate is constant from level to level. With this choice for hopping rates the model shows the same phase diagram as…

Statistical Mechanics · Physics 2013-11-12 Peter Mottishaw , Bartlomiej Waclaw , Martin R. Evans

Driven diffusive systems are often used as simple discrete models of collective transport phenomena in physics, biology or social sciences. Restricting attention to one-dimensional geometries, the asymmetric simple exclusion process (ASEP)…

Statistical Mechanics · Physics 2015-01-06 Diana Khoromskaia , Rosemary J. Harris , Stefan Grosskinsky

We develop a method for solving mathematical models of messenger RNA (mRNA) translation based on the totally asymmetric simple exclusion process (TASEP). Our main goal is to demonstrate that the method is versatile and applicable to…

Biological Physics · Physics 2020-05-19 Simon Scott , Juraj Szavits-Nossan

A totally asymmetric exclusion process on a ring with $\nu$ non-conserved internal degrees of freedom, where particles hop forward with a rate that depends on their internal state, has been studied. We show, using a mapping of the model to…

Statistical Mechanics · Physics 2010-11-16 Urna Basu , P. K. Mohanty

We consider the asymmetric simple exclusion processes (ASEP) on a ring constrained to produce an atypically large flux, or an extreme activity. Using quantum free fermion techniques we find the time-dependent conditional transition…

Statistical Mechanics · Physics 2015-05-20 V. Popkov , G. M. Schütz

We consider an interacting particle system, which generalizes the classical totally asymmetric simple exclusion process (TASEP), in that each site can contain up to a fixed finite number of particles, and the particle movement is governed…

Probability · Mathematics 2026-03-17 Yuliy Baryshnikov , Alexander Stolyar

The totally asymmetric simple exclusion process in discrete time is considered on finite rings with fixed number of particles. A translation-invariant version of the backward-ordered sequential update is defined for periodic boundary…

Soft Condensed Matter · Physics 2007-05-23 J. G. Brankov , Vl. V. Papoyan , V. S. Poghosyan , V. B. Priezzhev

Totally asymmetric simple exclusion process (TASEP) was originally introduced as a model for the traffic-like collective movement of ribosomes on a messenger RNA (mRNA) that serves as the track for the motor-like forward stepping of…

Statistical Mechanics · Physics 2019-08-14 Bhavya Mishra , Debashish Chowdhury

In this paper it is shown that the steady-state weights of the asymmetric simple exclusion process (ASEP) with open boundaries and parallel update can be written as a product of a scalar pair-factorized and a matrix-product state. This type…

Statistical Mechanics · Physics 2015-05-13 Marko Woelki , Michael Schreckenberg