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Deep neural networks have achieved remarkable breakthroughs by leveraging multiple layers of data processing to extract hidden representations, albeit at the cost of large electronic computing power. To enhance energy efficiency and speed,…

The evolution of the Internet and computer applications have generated colossal amount of data. They are referred to as Big Data and they consist of huge volume, high velocity, and variable datasets that need to be managed at the right…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-13 Youssef Bassil

In this paper we describe SYNERGY, which is a highly parallelizable, linear planning system that is based on the genetic programming paradigm. Rather than reasoning about the world it is planning for, SYNERGY uses artificial selection,…

Artificial Intelligence · Computer Science 2007-05-23 Ion Muslea

Recent DNA pre-alignment filter designs employ DRAM for storing the reference genome and its associated meta-data. However, DRAM incurs increasingly high energy consumption background and refresh energy as devices scale. To overcome this…

Emerging Technologies · Computer Science 2022-12-27 Fazal Hameed , Asif Ali Khan , Sebastien Ollivier , Alex K. Jones , Jeronimo Castrillon

Diffractive neural network (DNN), which can perform machine learning tasks based on the light propagation and diffraction, has recently emerged as a promising optical computing paradigm due to its high parallel processing speed and low…

Optics · Physics 2026-01-27 Yudong Tian , Haifeng Xu , Yuqing Liu , Xiangyu Zhao , Jierong Cheng , Chongzhao Wu

The vast parallelism, exceptional energy efficiency and extraordinary information inherent in DNA molecules are being explored for computing, data storage and cryptography. DNA cryptography is a emerging field of cryptography. In this paper…

Cryptography and Security · Computer Science 2011-01-14 D. Prabhu , M. Adimoolam

The combination of self-assembly and electronic properties as well as its true nanoscale dimensions make DNA a promising candidate for a building block of single molecule electronics. We argue that the intrinsic double helix conformation of…

Materials Science · Physics 2007-05-23 A. V. Malyshev

To train modern large DNN models, pipeline parallelism has recently emerged, which distributes the model across GPUs and enables different devices to process different microbatches in pipeline. Earlier pipeline designs allow multiple…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-08-23 Ziyue Luo , Xiaodong Yi , Guoping Long , Shiqing Fan , Chuan Wu , Jun Yang , Wei Lin

Training of deep neural networks (DNNs) is a computationally intensive task and requires massive volumes of data transfer. Performing these operations with the conventional von Neumann architectures creates unmanageable time and power…

Emerging Technologies · Computer Science 2020-01-08 Murat Onen , Brenden A. Butters , Emily Toomey , Tayfun Gokmen , Karl K. Berggren

DNA emerges as a promising medium for the exponential growth of digital data due to its density and durability. This study extends recent research by addressing the \emph{coverage depth problem} in practical scenarios, exploring optimal…

Information Theory · Computer Science 2024-02-01 Hadas Abraham , Rayn Gabrys , Eitan Yaakobi

The nucleotide sequence representation of DNA can be inadequate for resolving protein-DNA binding sites and regulatory substrates, such as those involved in gene expression and horizontal gene transfer. Considering that sequence-like…

Genomics · Quantitative Biology 2020-07-30 Jan Zrimec

Spurred by widening gap between data processing speed and data communication speed in Von-Neumann computing architectures, some bioinformatic applications have harnessed the computational power of Processing-in-Memory (PIM) platforms.…

Hardware Architecture · Computer Science 2020-08-17 Shaahin Angizi , Naima Ahmed Fahmi , Wei Zhang , Deliang Fan

A method for encoding information in DNA sequences is described. The method is based on the precision-resolution framework, and is aimed to work in conjunction with a recently suggested terminator-free template independent DNA synthesis…

Information Theory · Computer Science 2020-05-14 Siddharth Jain , Farzad Farnoud , Moshe Schwartz , Jehoshua Bruck

Cells control fluid flows with a spatial and temporal precision that far exceeds the capabilities of current microfluidic technologies. Cells achieve this superior spatio-temporal control by harnessing dynamic networks of cytoskeleton and…

Soft Condensed Matter · Physics 2025-05-26 Fan Yang , Shichen Liu , Heun Jin Lee , Rob Phillips , Matt Thomson

Cells receive a wide variety of cellular and environmental signals, which must be processed combinatorially to generate specific and timely genetic responses. We present here a theoretical study on the combinatorial control and integration…

Soft Condensed Matter · Physics 2007-05-23 Nicolas E. Buchler , Ulrich Gerland , Terence Hwa

Optical computing has reemerged as a promising alternative computing paradigm for providing energy-efficient information processing in the age of artificial intelligence. Among various photonic neural network platforms, diffractive optical…

Optics · Physics 2025-02-18 Bahadır Utku Kesgin , Firdevs Yüce , Uğur Teğin

With the growing model size, deep neural networks (DNN) are increasingly trained over massive GPU accelerators, which demands a proper parallelization plan that transforms a DNN model into fine-grained tasks and then schedules them to GPUs…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-24 Zhiqi Lin , Youshan Miao , Guodong Liu , Xiaoxiang Shi , Quanlu Zhang , Fan Yang , Saeed Maleki , Yi Zhu , Xu Cao , Cheng Li , Mao Yang , Lintao Zhang , Lidong Zhou

We describe a strategy for constructing codes for DNA-based information storage by serial composition of weighted finite-state transducers. The resulting state machines can integrate correction of substitution errors; synchronization by…

Information Theory · Computer Science 2016-11-18 Ian Holmes

Artificial synthesis of DNA molecules is an essential part of the study of biological mechanisms. The design of a synthetic DNA molecule usually involves many objectives. One of the important objectives is to eliminate short sequence…

Biomolecules · Quantitative Biology 2021-08-13 Zehavit Leibovich , Ilan Gronau

Motivated by DNA-based storage, we study the noisy shuffling channel, which can be seen as the concatenation of a standard noisy channel (such as the BSC) and a shuffling channel, which breaks the data block into small pieces and shuffles…

Information Theory · Computer Science 2019-03-01 Ilan Shomorony , Reinhard Heckel